Protein Alignment CG5027 and Txndc11

DIOPT Version :9

• Sequence 1: NP_648847.3
• Gene: CG5027 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_001121004.1
• Gene: Txndc11 / 302899
• RGDID: 1307538
• Length: 947
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 94/463 - (20%)
• Similarity: 165/463 - (35%)
• Gaps: 140/463 - (30%)

  Fly    26 SKVLELSDRFID----VRHEGQWLVM-FYAPWCGY------------------------------ 55
            |.||:|....:|    ||.:.:.:|: |||||||.
  Rat   101 SPVLDLFQGQLDYADHVRQDSEVVVLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAVNCWWNQ 165

  Fly    56 --CKKTEPIFALVAQALHATNVRVGRLDCTKYPAAA---KEFKVRGYPTIMFIKGN---MEFTYN 112
              |:|.:..|..  ..:|..:...|.:: .|.|.:|   ::|..|....:::|...   ::|..|
  Rat   166 GKCRKQKHFFYF--PVIHLYHRSFGPIE-YKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSN 227

  Fly   113 GDRGRDELVDYALRMSG---PPVQLVTRTESVDMLKGSH--TIFFIFVGQQEGVVWDTYYAAAEG 172
            .:.|   ::.| ...||   ||..|...|.::..||..:  |:.|       ||:.:.:.|....
  Rat   228 YEPG---VLGY-FEFSGSPQPPGYLTFFTSALHSLKKDYLGTVRF-------GVITNKHLAKLVS 281

  Fly   173 YQEHGFFYATSEDIAAQHFDFEKLPAVIVYKEEQHHFYPHGHLAHEMDPNEVNETVFQWVNVERF 237
            ....|..|      ..:||:     ..:|:..|..:|              ..|.:::|.:..:.
  Rat   282 LVHSGSVY------LHRHFN-----TSLVFPREVMNF--------------TAENIYKWASENQE 321

  Fly   238 TLFPKVTRFNIHQLLKTNK---------YLVLAVVQE-----DKLNQIATHELEFRD-----MVE 283
            |||..:.......||..|:         ::....:.|     |::.::|   ||:.:     :||
  Rat   322 TLFRWLQPHGGKSLLLNNELKKGPALFLFIPFDPLAERHPLLDEITEVA---LEYSNCRGDQVVE 383

  Fly   284 GVIRKHRARYHDKFQFGWIGEPSIAHSIILDQLPTP--HLIAINSSTQHHFIPEDDPMQMTPQAL 346
            .:::..|......||       |:|..:   |.|.|  .|:|.:.......:|:...:..|
  Rat   384 RLLQHLRRAEAPVFQ-------SLAPEL---QAPLPDAQLMAASPCCNTVVLPQGPALSRT---- 434

  Fly   347 HLFLESIRNESAIAYGGDTYFVRLNR-ALFEVRRALRDMWLGNPVLTTVIFGLPLGFLSLIMYSI 410
            |...|...|:|.   |.....|.:.: :.||:..||...:|.......|:.|           ||
  Rat   435 HNVCELCVNQSV---GTRPSSVSVPQCSFFEMAAALDSFYLKEQTFYRVVSG-----------SI 485

  Fly   411 FCGDCLVT 418
            .|.:.|.:
  Rat   486 ECSNFLTS 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5027	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	29/143 (20%)
		ER_PDI_fam	28..>355	CDD:273457	78/395 (20%)
Txndc11	NP_001121004.1	PDI_a_EFP1_N	93..205	CDD:239304	23/106 (22%)
		PDI_b_family	215..319	CDD:239279	27/139 (19%)
		Thioredoxin_6	254..396	CDD:290560	30/176 (17%)
		PDI_a_PDI_a'_C	660..762	CDD:239293

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350320
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930