DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5027 and Erp44

DIOPT Version :9

Sequence 1:NP_648847.3 Gene:CG5027 / 39775 FlyBaseID:FBgn0036579 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_001008318.1 Gene:Erp44 / 298066 RGDID:1309176 Length:406 Species:Rattus norvegicus


Alignment Length:360 Identity:78/360 - (21%)
Similarity:144/360 - (40%) Gaps:53/360 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 LLLTLGSTGLSSKVLELSDRFID--VRHEGQWLVMFYAPWCGYCKKTEPIFALVAQAL-----HA 72
            ||:|.....:::::..|....||  :.:....||.|||.||.:.:...|||...:..:     ..
  Rat    18 LLVTSIFAPITAEIASLDSENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDK 82

  Fly    73 TNVRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGN--MEFTYNGDRGRDELVDYALRMSGPPVQLV 135
            ..|...|:||.::...|:.:::..|||:...:..  |:..|.|.|....|.||..:....||..:
  Rat    83 NQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSNPVHEI 147

  Fly   136 TRTESVDMLKGSHTIFFIFVGQQEGVVWDTYYAAAEGYQEHGFFYATSEDIA-AQHFDFEKLPAV 199
            ...:.|..|..|......:..|::...:..:...|....:...|.:...|:: .:.:..:.|   
  Rat   148 QSLDEVTNLDRSKRNIIGYFEQKDSDNYRVFERVASILHDDCAFLSAFGDLSKPERYSGDNL--- 209

  Fly   200 IVYKEEQHHFYPHGHLAHEMD--PNEVN-ETVFQWVNVERFTLFPKVTRFNIHQLLKTN-KYLVL 260
             :||       |.|....:|.  .:..| :..|.|:..:...|..::|..|..:|.:.. .:|:|
  Rat   210 -IYK-------PPGRSVPDMVYLGSMTNFDVTFNWIQDKCVPLVREITFENGEELTEEGLPFLIL 266

  Fly   261 AVVQEDKLNQIATHELE-FRDMVEGVIRKHRARYH------DKFQFGWIGEPSIAHSIILDQLPT 318
            ..::||      |..|| |::.|...:...:...:      |||:          |.::..| .|
  Rat   267 FHMKED------TESLEIFQNEVARQLISEKGTINFLHADCDKFR----------HPLLHIQ-KT 314

  Fly   319 P---HLIAINSSTQHHFIPEDDPMQMTPQALHLFL 350
            |   .:|||: |.:|.::..|....:.|..|..|:
  Rat   315 PADCPVIAID-SFRHMYVFGDFKDVLIPGKLKQFV 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5027NP_648847.3 PDI_a_TMX3 27..128 CDD:239298 28/109 (26%)
ER_PDI_fam 28..>355 CDD:273457 75/347 (22%)
Erp44NP_001008318.1 PDI_a_ERp44 29..136 CDD:239294 27/106 (25%)
PDI_b_ERp44 144..234 CDD:239368 15/100 (15%)
Thioredoxin_6 167..350 CDD:290560 42/211 (20%)
PDI_b'_ERp44 245..355 CDD:239370 28/122 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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