Protein Alignment Tmx3 and C14B9.2

DIOPT Version :10

• Sequence 1: NP_648847.3
• Gene: Tmx3 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_498775.2
• Gene: C14B9.2 / 176147
• WormBaseID: WBGene00015752
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 299
• Identity: 73/299 - (24%)
• Similarity: 125/299 - (41%)
• Gaps: 47/299 - (15%)

  Fly    45 LVMFYAPWCGYCKKTEPIFALVAQALHA--TNVRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGNM 107
            ||.|||||||:|||..|.:...||.|.|  :.|::|::|.|.......::.|.||||:..|:...
 Worm   168 LVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTMKIIRNGR 232

  Fly   108 EFTYNGDRGRDELVDYALRMSGPPVQLVTRTESVDMLKGSHTIFFI-FVGQQEGVVWDTYYAAAE 171
            .|.|||.|....::.|....|.|..:.:.:.:.|:.......:..| |...::...::.:..:||
 Worm   233 RFDYNGPREAAGIIKYMTDQSKPAAKKLPKLKDVERFMSKDDVTIIGFFATEDSTAFEAFSDSAE 297

  Fly   172 GYQEHGFFYATSEDIAAQHFDFEKLPA----VIVYKEEQHHFYPHGHLAH-EMDPNE-------- 223
            ..:|.......:.|.||    |:|..|    :|:       |||  .|.| :.:|..
 Worm   298 MLREEFKTMGHTSDPAA----FKKWDAKPNDIII-------FYP--SLFHSKFEPKSRTYNKAAA 349

  Fly   224 VNETVFQWVNVERFTLFPKVTRFNIHQLLKTNKYLVLAVVQEDKLNQIATHELEFRDMVEGVIRK 288
            .:|.:..:.......|..|:|:.|. ....|.|.||:.....|...|.......:|..|..:.:|
 Worm   350 TSEDLLAFFREHSAPLVGKMTKKNA-ATRYTKKPLVVVYYNADFSVQYREGSEYWRSKVLNIAQK 413

  Fly   289 HRARYHDKFQFG--------------WIGEPSIAHSIIL 313
            ::   .||::|.              .:|:..:.|::::
 Worm   414 YQ---KDKYKFAVADEEEFAKELEELGLGDSGLEHNVVV 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmx3	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	33/84 (39%)
		ER_PDI_fam	28..>355	CDD:273457	73/299 (24%)
C14B9.2	NP_498775.2	pdi_dom	41..138	CDD:273454
		ER_PDI_fam	147..616	CDD:273457	73/299 (24%)