Protein Alignment Tmx3 and pdi-3

DIOPT Version :10

• Sequence 1: NP_648847.3
• Gene: Tmx3 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_491995.1
• Gene: pdi-3 / 172433
• WormBaseID: WBGene00003964
• Length: 488
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 83/324 - (25%)
• Similarity: 136/324 - (41%)
• Gaps: 70/324 - (21%)

  Fly     6 MWIFGLISALLLTLGSTGLSSKVLELSDRFID--VRHEGQWLVMFYAPWCGYCKKTEPIFALVAQ 68
            :|:...:.|..|...|.|  ..|||.:|...|  ::.....||.|||||||:|||..|.:...|.
 Worm     2 IWVQAALVASFLAFASAG--GAVLEYTDGNFDDLIQTHDIALVKFYAPWCGHCKKIAPEYERAAP 64

  Fly    69 ALHATN---VRVGRLDCTKYPAAAKEFKVRGYPTI-MFIKGNMEFTYNGDRGRDELVDYALRMSG 129
            .| |:|   |.:.::|||.......:|.|:|:||: :|..|.....|:|.|..|.:|.:....||
 Worm    65 KL-ASNDPPVALVKVDCTTEKTVCDKFGVKGFPTLKIFRNGVPAQDYDGPRDADGIVKFMRGQSG 128

  Fly   130 P-PVQLVTRTESVDMLKGSHTIFFIFVGQQEGVVWDTYYAAAEGYQEH-GFFYATSEDI--AAQH 190
            | ..:|.|..|......|...:...|. :.|..:.|:|...|:..::. .|.:.:::||  .|.:
 Worm   129 PSSKELKTVAEFEKFTGGDENVVIGFF-ESESKLKDSYLKVADTERDRFSFAHTSNKDIIKKAGY 192

  Fly   191 FDFEKLPAVIVYKEEQHHFYPHGHLAHEMDPNE----------------VNETV----------- 228
            .|     .|:|:..::.|        ::.|.||                |:|||
 Worm   193 SD-----DVVVFVPKKLH--------NKFDTNEFKYDGNYDTDKIKNFLVHETVGFAGIRTQGNL 244

  Fly   229 FQ---------WVNVERFTLFPKVTRFNIHQLLKTNKYLVLAVVQEDKLNQIATHELEFRDMVE 283
            ||         :.||: :...||.:.:      ..|:.|.:|...:.|:....:::.||...:|
 Worm   245 FQFEQKPIVIVYYNVD-YVKDPKGSNY------WRNRVLKVAQNYKRKVQFAVSNKEEFSSEIE 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmx3	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	38/106 (36%)
		ER_PDI_fam	28..>355	CDD:273457	78/302 (26%)
pdi-3	NP_491995.1	ER_PDI_fam	21..477	CDD:273457	78/303 (26%)