Protein Alignment Tmx3 and Pdi

DIOPT Version :10

• Sequence 1: NP_648847.3
• Gene: Tmx3 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: XP_061510732.1
• Gene: Pdi / 1280308
• VectorBaseID: AGAMI1_010164
• Length: 549
• Species: Anopheles gambiae
• Alignment Length: 366
• Identity: 89/366 - (24%)
• Similarity: 166/366 - (45%)
• Gaps: 52/366 - (14%)

  Fly    11 LISA--LLLTLGSTGLSSK-------VLELS-DRFIDVRHEGQW-LVMFYAPWCGYCKKTEPIFA 64
            |:||  |:|...:..|:::       ||.|: |.|..|....:: ||.|||||||:||...|.:|
Mosquito     3 LLSAFGLVLAFATVALAAEEVKTEDGVLVLTKDNFDSVIANNEFVLVEFYAPWCGHCKALAPEYA 67

  Fly    65 LVAQAL--HATNVRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGNMEFTYNGDRGRDELVDYALRM 127
            ..|:.|  ..:|:::.::|.|..|..|:::.:|||||:.|.:...:..|.|.|.:|.:|.:..:.
Mosquito    68 KAAKVLADKESNIKLAKVDATVEPELAEKYGIRGYPTLKFFRSGSQVDYTGGREQDTIVSWLEKK 132

  Fly   128 SGPPV-QLVTRTESVDMLKGSHTIFFIFVGQQEGVVWDTYYAAAEGYQEHGFFYATSEDIAAQHF 191
            :||.. :|.|...:.:.||.::.....|...::......:.:.|....::.|...:||::.|::
Mosquito   133 TGPAAKELETVEAAEEFLKENNVAVVGFFKDRDSKEAKAFMSTAVAVDDYPFGVTSSEEVYAKY- 196

  Fly   192 DFEKLPAVIVYKEEQHHFYPHGHLAHEMDPNEVNETVFQWVNVERFTLFPKVTRFNIHQLL--KT 254
             ..|..:||::|    || ..|....|.:..|  |.:.::|..:...|....:.....::.  :.
Mosquito   197 -EAKCGSVILFK----HF-DEGKAVFEGEATE--EALKKFVTAQALPLIVDFSHETAQKIFGGEI 253

  Fly   255 NKYLVLAVVQEDKLNQIATHELEFRDMVEGVIRKHRARYHDKFQFGWIGEPSIAHSIIL------ 313
            ..:|:..:.:|      |.|..||.:..:.|.:|.|    ::..|..|......|:.||
Mosquito   254 KSHLLFFISKE------AGHLKEFVEPAKEVAKKFR----EQILFVTIDADQEDHTRILEFFGMK 308

  Fly   314 -DQLPTPHLIAINSSTQHHFIPEDDPMQMTPQALHLFLESI 353
             |::|:..:|.:          |:|..:..|:...|..:.|
Mosquito   309 KDEVPSLRIIRL----------EEDMAKYKPETNDLSADKI 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmx3	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	37/111 (33%)
		ER_PDI_fam	28..>355	CDD:273457	83/340 (24%)
Pdi	XP_061510732.1	None