DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tmx3 and Txndc5

DIOPT Version :10

Sequence 1:NP_648847.3 Gene:Tmx3 / 39775 FlyBaseID:FBgn0036579 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_001258259.1 Gene:Txndc5 / 100362805 RGDID:2323973 Length:417 Species:Rattus norvegicus


Alignment Length:182 Identity:55/182 - (30%)
Similarity:82/182 - (45%) Gaps:29/182 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 LSSKVLELSDRFIDVR-HEGQWLVMFYAPWCGYCKKTEPIFALVAQAL-HATNVRVGRLDCTKYP 86
            |...:.|||....::. .:|...:.|:|||||:||...|.:..:|..| |:..|::|::|||::.
  Rat   173 LKQGLYELSANNFELHVSQGNHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHY 237

  Fly    87 AAAKEFKVRGYPTIMFIK-GNMEFTYNGDRGRDELVDYALRMSGPPVQLVTRTESVDMLKGSHTI 150
            |...|.:||||||:::.: |.....|.|.|..:.|.||        ||        ..|:||...
  Rat   238 AVCSEHQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDY--------VQ--------SQLQGSEAA 286

  Fly   151 FFIFVGQQEGVVWDTYYAAAEGYQEHGFFYATS----EDIAAQHFDFEKLPA 198
            .......:..|:      |||...:.|...|.:    ||..||...|.|..|
  Rat   287 PETVEPSEAPVL------AAEPPGDKGTVLALTEKSFEDTIAQGITFVKFYA 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tmx3NP_648847.3 PDI_a_TMX3 27..128 CDD:239298 36/103 (35%)
ER_PDI_fam 28..>355 CDD:273457 54/178 (30%)
Txndc5NP_001258259.1 PDI_a_ERp46 47..150 CDD:239303
PDI_a_ERp46 176..276 CDD:239303 36/107 (34%)
PDI_a_ERp46 308..409 CDD:239303 8/25 (32%)
Blue background indicates that the domain is not in the aligned region.

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