DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Taf4 and TAF4

DIOPT Version :9

Sequence 1:	NP_001137958.1	Gene:	Taf4 / 39765	FlyBaseID:	FBgn0010280	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	NP_013718.1	Gene:	TAF4 / 855017	SGDID:	S000004607	Length:	388	Species:	Saccharomyces cerevisiae

Alignment Length:	457	Identity:	105/457 - (22%)
Similarity:	178/457 - (38%)	Gaps:	109/457 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   667 NSVPTANKLTAVKVGQT-QIKAITPSLHP-----PSLAAISGGPPPTP-----TLSVLSTLNSAS 720
            ||....:..|.|....| :.:...|...|     |..|:......|:|     |..|.||.|.|:
Yeast     3 NSPKKPSDGTGVSASDTPKYQHTVPETKPAFNLSPGKASELSHSLPSPSQIKSTAHVSSTHNDAA 67

  Fly   721 TTT----LPIPSLPTVHLPPEALRAREQMQNSLNHNSNHFDAKLVEIKAPSLHPPHMERINASLT 781
            ..|    ||....||.:|..|:           |.::|                      |...:
Yeast    68 GNTDDSVLPKNVSPTTNLRVES-----------NGDTN----------------------NMFSS 99

  Fly   782 PIGAKTMARPPPAINKAIGKKKRDAMEMDAKLNTSSGGAASAANSFFQQSSMSSMYGDDDINDVA 846
            |.|.....:.....||  |..|.|:  .|.|.:.|||..|.      |||..:.|      .||.
Yeast   100 PAGLALPKKDDKKKNK--GTSKADS--KDGKASNSSGQNAQ------QQSDPNKM------QDVL 148

  Fly   847 AMGGVNLAEESQRILGCTENIG-TQIRSCKDEVFLNLPSLQAR-----IRAITSEAGLD-EPSQD 904
            ...|:::.|| :.:|..:.|.. :|:::...::..:||.|...     :|.:..|...: .|:::
Yeast   149 FSAGIDVREE-EALLNSSINASKSQVQTNNVKIPNHLPFLHPEQVSNYMRKVGKEQNFNLTPTKN 212

  Fly   905 VAVL--ISHACQERLKNIVEKLAVIAEHRIDVIKLDPRYEPAKDVRGQIKFLEELDKAEQKRHEE 967
            ..:|  :|.||:..:::|:....||:.||...:|::....  .:|...::.:..:.|.|::|  .
Yeast   213 PEILDMMSSACENYMRDILTNAIVISRHRRKAVKINSGRR--SEVSAALRAIALIQKKEEER--R 273

  Fly   968 LEREMLLRAAKSRSRVEDPEQAKMKARAKEMQRAEMEELRQRDANLTALQAIGPRKKLKLDGETV 1032
            :::.:.|...|     ||.|           .:.:.||...|.:|:||....|.:|:.   |...
Yeast   274 VKKRIALGLEK-----EDYE-----------NKIDSEETLHRASNVTAGLRAGSKKQY---GWLT 319

  Fly  1033 SS-------GAGSSGGGVLSSSGSAPTTLRPRIKR----VNLRDMLFYMEQEREFCRSSMLFKTY 1086
            ||       ||.|||......:....:.|:.|..|    :.:||:||.:|..|...: :::.|.|
Yeast   320 SSVNKPTSLGAKSSGKVASDITARGESGLKFREAREEPGIVMRDLLFALENRRNSVQ-TIISKGY 383

  Fly  1087 LK 1088
            .|
Yeast   384 AK 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Taf4	NP_001137958.1	TAFH	460..550	CDD:197785
Taf4	NP_001137958.1	TAF4	842..1084	CDD:283017	58/261 (22%)
TAF4	NP_013718.1	TAF4	144..383	CDD:398763	60/269 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344754
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2341
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105779
Panther	1	1.100	-	-	LDO	PTHR15138
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830