DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Taf4 and TAF4

DIOPT Version :9

Sequence 1:	NP_001137958.1	Gene:	Taf4 / 39765	FlyBaseID:	FBgn0010280	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	NP_001190458.1	Gene:	TAF4 / 834330	AraportID:	AT5G43130	Length:	852	Species:	Arabidopsis thaliana

Alignment Length:	932	Identity:	191/932 - (20%)
Similarity:	343/932 - (36%)	Gaps:	263/932 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 NNSINATTNTTTTTTTNNNNKPATNQQQQQQK--------LQQQQHLKAQQQQKQQQASAAAAAA 359
            |..|..:..|:....||..|..::.||....|        ..|.||.....|.|:|:.|..
plant    31 NRDIEGSMTTSIPHVTNPGNNHSSRQQFSTWKNGIGDSNINVQTQHSLESTQMKEQEGSTL---- 91

  Fly   360 AAAANVAATIKIKQNSMTNTTATSNIIVNSVASSGYANSSQPPHLTQLNAQAPQLPQITQIQTIP 424
                         :|...:....:|                .||| |.| |...|.:..|:...|
plant    92 -------------ENQHQHDLKRAN----------------EPHL-QHN-QPQDLHRAGQLWENP 125

  Fly   425 AQQSQQQQVNNVSSAGGTATAVSSTTAATTTQQGNTKEKCRKFLANLIELSTREPKPVEKNVRTL 489
            :|..|           .|...:|...........:..::.......|.::|:::.:.||..|..:
plant   126 SQVPQ-----------STGLPISEKNPTGNESDRSHNQESESQYMKLQKMSSQQARGVEPPVNPM 179

  Fly   490 IQELVNANVEPEEFCDRLERLLNASPQPCLIGFLKKSLPLLRQALYTK----ELVIEGIKPPPQH 550
            ....:|.|.:...|...|..|:|.         |.|...|..:.||.:    |:..||.   .:|
plant   180 NVNPINRNPKQVPFAALLPTLMNQ---------LDKDRALQLRTLYARLKKNEIPKEGF---TRH 232

  Fly   551 VLGLAGLSQQLPKIQAQIRPIGPSQTTTIGQTQVRMITPNALGTPRPTIGHTTISKQPPNIRLPT 615
            :..:.| .|.|....::::.:..:|              ..:|...|:   |.|:.|    :..:
plant   233 MKDIVG-DQMLRMAVSKLQQVNYNQ--------------GKIGIQAPS---TEINNQ----KSQS 275

  Fly   616 APRLVNTGGIRTQIPSLQVPGQANIVQIRG----PQHAQLQRTGSVQIRATTRPPNSVP---TAN 673
            .||.|:.    .|:||.......:.|.::|    ||| |:|           .||:|.|   |:.
plant   276 DPRAVHL----NQLPSSASGTLGSSVPVQGLTKHPQH-QMQ-----------HPPSSFPMYTTSG 324

  Fly   674 KLTAVKVGQTQIKAIT--PSLHPPSLAAIS----------GGPPPT-------PTLSVLSTLNSA 719
            ...:.....|.....|  |.||...:..::          ||||.:       |.....|::|..
plant   325 SFHSFPGPNTNASGSTLRPHLHDSHMRHVAHNQPMGSTGLGGPPQSTTNMMTMPKFERPSSVNDP 389

  Fly   720 S------------TTTLPIPSLP-----TVHLPPEALRAREQMQNSLNHNSN---HFDAKLVEIK 764
            |            :::||:.|.|     ..|:..|::....:..|:.:..||   ..::..:.:.
plant   390 SRVQGGATSHFQNSSSLPLNSAPGQGSSVSHVKQESVDQSFEKNNAASMTSNEDLEKESSRMVLS 454

  Fly   765 AP-------SLHPPHMERINASLT-----PIGAK---TMARPPPAINKAIGKKKRDAMEMDAKLN 814
            .|       |:.|....:::||.|     |:|..   ..||.||. ..::|:||        .|.
plant   455 TPNNMAPASSVSPSMTTQLDASTTMNSRGPLGTSQGGANARMPPK-KPSVGQKK--------PLE 510

  Fly   815 TSSGGAASAANSFFQQSSMSSM-YGDDDINDVAAMGGVNLAEESQRILGCTENIG-------TQI 871
            |.  |::....|..|:.:.:|| ...:.:|||.|:.||||.||.:::....:..|       ..:
plant   511 TL--GSSPPPPSKKQKVAGNSMDQSIEQLNDVTAVSGVNLREEEEQLFSGAKEDGRVSEASRRVV 573

  Fly   872 RSCKDEVFLNLPSLQARIRAITSEAGLDEPSQDVAVLISHACQERLKNIVEKLAVIAEHRIDVIK 936
            ...::.:.|....||.::..|.::|||.:.|.||...:|...:||::.::..:..:::.|:|..|
plant   574 HEEEERLILQKNPLQRKLAEIMAKAGLKQISNDVERCLSLCVEERMRGLLSHIIRLSKQRVDAEK 638

  Fly   937 LDPRYEPAKDVRGQIKFLEELDKAE-QKRHEELEREMLLRAAKSRSRVE------DPEQAKMKAR 994
            ...|.....|:|.||..:.:..|.| :|:..|.|:      .|..|..|      |.|:.|...|
plant   639 SRHRTFITSDIRLQINEMNQKVKEEWEKKQAEAEK------LKKPSESEEGDGGVDSEKDKEDNR 697

  Fly   995 AKEMQ--RAEMEELRQRDANLTALQAI-----------------------------------GPR 1022
            :|.::  :.:.:::|...||:.|..|:                                   |..
plant   698 SKGVKGNKEDDDKMRTTAANVAARAAVGGDDAFLKWQLMAEARQKSVSEAGKDGNQKTTSGGGKN 762

  Fly  1023 KKLKLDGETVSSGAGSSGG-------------------GVLSSSG-----SAPTTLRPRIKR-VN 1062
            .|.:.||....||..||.|                   |.|.:.|     :..::|:|::.| ::
plant   763 SKDRQDGGRRFSGTESSCGVGIVYRVSSSRFWFAMMSFGFLFAGGRRVGKNQGSSLQPKVVRTIS 827

  Fly  1063 LRDMLFYMEQEREFCRSSMLFK 1084
            ::|::..:|:|.:..:|:::::
plant   828 VKDVVAVLEREPQMSKSTLMYR 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Taf4	NP_001137958.1	TAFH	460..550	CDD:197785	19/93 (20%)
Taf4	NP_001137958.1	TAF4	842..1084	CDD:283017	69/317 (22%)
TAF4	NP_001190458.1	Med15	<82..529	CDD:255446	108/553 (20%)
		RST	187..250	CDD:288985	17/75 (23%)
		TAF4	537..850	CDD:283017	69/319 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I3516
eggNOG	1	0.900	-	-		E1_KOG2341
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2381
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001841
OrthoInspector	1	1.000	-	-		otm3435
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15138
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.050