Protein Alignment Taf4 and taf4b

DIOPT Version :10

• Sequence 1: NP_001137958.1
• Gene: Taf4 / 39765
• FlyBaseID: FBgn0010280
• Length: 1088
• Species: Drosophila melanogaster
• Sequence 2: XP_002940973.3
• Gene: taf4b / 100487219
• XenbaseID: XB-GENE-995003
• Length: 892
• Species: Xenopus tropicalis
• Alignment Length: 1163
• Identity: 322/1163 - (27%)
• Similarity: 465/1163 - (39%)
• Gaps: 385/1163 - (33%)

  Fly    13 TFTSQPLPN-------GTISIAGNPGAVIS---------------------------TAQLPNTT 43
            ||.:.|.|:       ..:|:|..|.|::|                           .::.|.||
 Frog    28 TFPAAPSPDLPTKSVQTPVSVALAPAALLSKVAPVLVTSQATKVRGGPRMPAPQHVMASKAPQTT 92

  Fly    44 TIKTIQAGIGGQHQGLQQVHHVQQQQQSQQQQQQQQQTQSVGATQTQTLVIKSNHHAVTLPAGLV 108
            .|: |.||.........|:..|.||..:      :.|.|:.||   |.|...:|....|.|...:
 Frog    93 AIQ-IPAGTVLIRSSTGQLMLVSQQTLA------RVQAQNPGA---QVLSNLTNSAVKTTPLTTI 147

  Fly   109 SSAPAGIVTMTKTINQAGQPLLNSMLPAGVV-----VGMRQQA------------PSQQQQKNV- 155
            |.||        .:.::..||..|.|.:.:.     :|.||.|            ||..|..:|
 Frog   148 SIAP--------NVQRSPSPLQTSSLTSSLAKVTSSMGSRQNAPVSLPAVVRICTPSTPQTTSVS 204

  Fly   156 PTNPLSRVVINSHMAGVRPQSPSITLSTLNTGQTPALLVKTDNGFQLLRVGTTTGPPTVTQTITN 220
            .|...|.|||       :...|::|..| |...|.|..|.. .|..::...:..||.|.:.|:..
 Frog   205 STQGTSTVVI-------KAPGPAVTALT-NISSTSASSVSA-TGSVVIPANSVMGPGTSSITVLP 260

  Fly   221 TSNNSNTTSTTNHPTTTQIRLQT-----VPAAAVSRYQQQQQHQQQSQQQQQSQQQQHATSTTAS 280
            .|.::        |..|.|.:.|     :|:|:|:        ...||...:|           |
 Frog   261 ISAST--------PVITPITINTCTSAVIPSASVT--------PSVSQNPIRS-----------S 298

  Fly   281 TSIALRKTIVRTSSTVPSSNNNNNSINATTNTTTTTTTNNNNKPATNQQQQQQKLQQQQHLKAQQ 345
            .|.::|.|   |.|::||.     .|.|.::|.|.|..:.....|||
 Frog   299 LSASVRTT---TPSSIPSV-----KIYAPSSTLTATCGSAIKLKATN------------------ 337

  Fly   346 QQKQQQASAAAAAAAAAANVAATIKIKQNSMTNTTATSNII-----------VNSVASSGYANSS 399
                  ......||...::|..:..|:.:|:.....:.|.:           |.|.|.||..:.:
 Frog   338 ------LYITTTAAGTCSSVTTSNTIQASSVITPVLSENCVPQVRPAQGQIKVLSGAPSGVPSKT 396

  Fly   400 QPPHLTQLNAQAPQLPQITQIQTIPAQQSQQQQVNNVSSAGGTATAVSSTTAATTTQQGNTKEKC 464
            .||.:.               ||.|.|.| .:.::||                         :||
 Frog   397 GPPKMA---------------QTTPTQNS-PEILDNV-------------------------KKC 420

  Fly   465 RKFLANLIELSTREPK--PVEKNVRTLIQELVNANVEPEEFCDRLERLLNASPQPCLIGFLKKSL 527
            :.|||.||:|::..|:  .:.:||:.|::.|:::::|||||..:|.:.|.:||||.|:.||||||
 Frog   421 KNFLATLIKLASSGPQSPTMGQNVKNLVKSLLDSDIEPEEFTAKLYKELKSSPQPYLVPFLKKSL 485

  Fly   528 PLLRQALYTKELVIEGIKPPPQHVLGLAGLSQQLPKIQAQIRPIGPSQTTTIGQTQVRMITPNAL 592
            |.|||.                           :|..|..|...|..
 Frog   486 PALRQL---------------------------MPNSQEFIMQCGQQ------------------ 505

  Fly   593 GTPRPTIGHT-TISKQPPNIRLPTAPRLVNTGGIRTQIPSLQVPGQANIVQIRGPQHAQLQRTGS 656
             ||:|...:: ::.|..|...|....::.:|.|                       :|:.|:|.|
 Frog   506 -TPQPPANNSVSLVKSTPTFSLQAGKQIGSTIG-----------------------NAKFQQTTS 546

  Fly   657 VQIRATTRPPNSVPTANKLTAVKVGQTQIKAITPSLHPPSLAAISGGPPPTPTLSVLSTL----- 716
                |||:|..:|.|.|           ||.:......|      ||.....:||..|||
 Frog   547 ----ATTKPIGTVKTVN-----------IKQVVLQQQSP------GGNLKQVSLSQNSTLTIQKP 590

  Fly   717 --NSASTTTLPIPSLPTVHLPPEALRAREQMQNSLNHNSNHFDAKLVEIKAPSLHPPHMERINAS 779
              |..|...|    :...||||.::..:..:..:          |::.::|..||
 Frog   591 GENRVSLNAL----IQASHLPPGSILKQITIPGN----------KVISVQAAPLH---------- 631

  Fly   780 LTPIGAKTMARPPPAINKAIGKKKRDAMEMDAKLNTSSGGAASAANSFFQQSSMSSMYGDDDIND 844
                                                             .:.|.:|...:|||||
 Frog   632 -------------------------------------------------IKESGTSFREEDDIND 647

  Fly   845 VAAMGGVNLAEESQRILGC-TENIGTQIRSCKDEVFLNLPSLQARIRAITSEAGLDEPSQDVAVL 908
            |.:|.||||:|||..||.. :|.:|..|||||||.||...:||.||..|.....:.|.:.||..|
 Frog   648 VTSMAGVNLSEESACILAANSELVGAVIRSCKDEPFLFTSALQNRILDIGKRHDIKELNSDVMNL 712

  Fly   909 ISHACQERLKNIVEKLAVIAEHRIDVIKLDPRYEPAKDVRGQIKFLEELDKAEQKRHEELEREML 973
            :|||.||||:.::|||.:.|:||....|...||....|||.|:||||:|:..|::|..|.|||||
 Frog   713 VSHATQERLRGLIEKLTLAAQHRSTNYKQSDRYLKYSDVRAQLKFLEQLEHLEKQRRNEEEREML 777

  Fly   974 LRAAKSRSRVEDPEQAKMKARAKEMQRAEMEELRQRDANLTALQAIGPRKKLKLDG--------E 1030
            ||||||||..|||||.::|.:|||:|:.|:|:::.|:||||||.|||||||..||.        |
 Frog   778 LRAAKSRSNREDPEQLRLKQKAKELQQMELEQIQYREANLTALAAIGPRKKRPLDSLCLHNGWDE 842

  Fly  1031 TVSSGAGSSGGGVLSSSGSAPTTLRPRIKRVNLRDMLFYMEQEREFCRSSMLFKTYLK 1088
            |:.||:...|   ||.|     .|.|||.||:|||::|.||||||...|..|::..||
 Frog   843 TIPSGSTIFG---LSKS-----LLVPRITRVSLRDLIFCMEQERESKHSLSLYRALLK 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf4	NP_001137958.1	TAFH	460..550	CDD:197785	35/91 (38%)
		PHA03378	<500..>742	CDD:223065	61/249 (24%)
		TAF4	842..1084	CDD:461598	129/250 (52%)
taf4b	XP_002940973.3	PHA03247	<8..520	CDD:223021	150/664 (23%)
		TAFH	416..507	CDD:462195	41/161 (25%)
		TAF4	645..889	CDD:461598	129/251 (51%)