DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zn72D and adad2

DIOPT Version :9

Sequence 1:	NP_001261924.1	Gene:	Zn72D / 39764	FlyBaseID:	FBgn0263603	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	XP_687183.1	Gene:	adad2 / 558824	ZFINID:	ZDB-GENE-130530-788	Length:	517	Species:	Danio rerio

Alignment Length:	163	Identity:	38/163 - (23%)
Similarity:	63/163 - (38%)	Gaps:	45/163 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   625 LKEVAGDTQVNYRV-EVNAEEAALIVLDESVSVKIT---------LTSP-----LLRDANPGEAA 674
            |.:|.|.:.|.::. ||.:.::...:.|...|..:|         :|:|     ||.||..| :.
Zfish    68 LDDVEGQSSVGHQTQEVQSPDSPPQMEDLGSSSDVTSLSGWSLSSVTAPEATVDLLEDATDG-SL 131

  Fly   675 TTDEGEGDSEFLPREPCLRALADLRHAKWFQARATGLQSCV-MVIRILRDLCQRVSSWQSLPQWS 738
            |.|:..|                ::.|.|.:.|.|.|  |. ...::||: |....|.:|.   .
Zfish   132 TRDQRTG----------------VKFADWHKNRVTAL--CTGRFDKLLRE-CPEYHSTKSC---F 174

  Fly   739 LELLVEKVISSAGFPISPGD-CMRRIMEALSSG 770
            ...::|:.:...|     |. |....:.||.||
Zfish   175 AAFVLEREVRDTG-----GQRCENYEVVALGSG 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732
		C2H2 Zn finger	207..229	CDD:275371
		ZnF_U1	252..284	CDD:197732
		C2H2 Zn finger	255..277	CDD:275371
		ZnF_U1	368..396	CDD:197732
		C2H2 Zn finger	368..390	CDD:275371
		DZF	577..829	CDD:128842	38/163 (23%)
adad2	XP_687183.1	A_deamin	198..509	CDD:280326	4/5 (80%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594018
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930