Protein Alignment Zn72D and zfr

DIOPT Version :10

• Sequence 1: NP_788510.1
• Gene: Zn72D / 39764
• FlyBaseID: FBgn0263603
• Length: 884
• Species: Drosophila melanogaster
• Sequence 2: XP_012816329.1
• Gene: zfr / 496597
• XenbaseID: XB-GENE-6067390
• Length: 1084
• Species: Xenopus tropicalis
• Alignment Length: 1130
• Identity: 421/1130 - (37%)
• Similarity: 547/1130 - (48%)
• Gaps: 327/1130 - (28%)

  Fly     1 MANNNYAGFNYG-GTQYNTGQVSYPAVTNATYANAAAYQNAAVAAG--QGGYGGAAGAGAGATSG 62
            ||..||.||.:| ..||:....|..|.::.|...:.....|.|||.  ...|..||...|.|...
 Frog    23 MATGNYFGFTHGAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPA 87

  Fly    63 P-------GAGGYGGY------GDY----------------------------RS---AMQYDAT 83
            |       .|..||||      .||                            ||   |:.|| :
 Frog    88 PVAVAAAATAAAYGGYPAAHTATDYGYTQRQQEAPPPPPPVTTQNYQDSYSYVRSTAPAVAYD-S 151

  Fly    84 KTFYQQSPASYNASGS-TASVSKTHYSAPPV--KNQVKGKMDKSNGGP--------------KPP 131
            |.:|||..|:..|:.. ..:|::|:|...|:  ...|..|...|.|..              ||.
 Frog   152 KQYYQQPTATVAAAAQPQPAVAETYYQTAPIALSLPVAPKAGYSQGAAQYTQAQQTRQVTAIKPA 216

  Fly   132 SSAPP---------------------------------------AGNNYSGYDTALYNAASMYVA 157
            :.:|.                                       :|..||||:.|:|:|||.|..
 Frog   217 NPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTAVTYSGAAYSGYEAAVYSAASSYYQ 281

  Fly   158 QQHQGNPNQKPNGGANNWYQRKMGATIPGATAI----------------RGMRPKAPPRPQQLHY 206
            ||.|              .|:|..|....|.|.                :.::||.||:|.|:||
 Frog   282 QQQQ--------------QQQKQAAAAAAAAATAAWTGTNFTKKPQFQNKQLKPKQPPKPPQIHY 332

  Fly   207 CEVCKISCAGPQTYREHLEGQKHKKREASLKMS---ASANSATQNRGNNYHCELCDVTCTGTDAY 268
            |:||||||||||||:||||||||||:||:||.|   .|:::|.:...|...||||||:|||.|||
 Frog   333 CDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQNTTSSSTAVRGTQNQLRCELCDVSCTGADAY 397

  Fly   269 AAHVRGAKHQKVVKLHQKLGKPIPSEEPKKMGKINFVPAAAGGAGVAK------TEGGANESDAA 327
            |||:||||||||||||.||||||||.||      |.|..:...|.|:|      :..|||.|.:.
 Frog   398 AAHIRGAKHQKVVKLHTKLGKPIPSTEP------NVVSQSVTSAAVSKPSTTSSSTSGANGSSSV 456

  Fly   328 G------------------------------------------------DLDDNLDDS------- 337
            |                                                ...:.:|||
 Frog   457 GASPSVKLLTSSSSLSTSSSSKASSMSSTSIVKKVTTPKITFIGGNKLQSTGNKVDDSKMSDSAK 521

  Fly   338 -----------------------LGENTDNIKPVGGEYIEEVKDEEGKILSFNCKLCDCKFNDPN 379
                                   |.....:::|||.:|:|||:::|||::.|:||||:|.|||||
 Frog   522 TTPSTAAQTQEAKIDPMSEAAQTLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPN 586

  Fly   380 AKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMSSHRGGDDHDGGYWE---- 440
            |||||:||||||||||:||.|||.|:.||:.|.|::.|.:..:.|....         ||.
 Frog   587 AKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEE---------YWRRREE 642

  Fly   441 ------EQRNR-----------------QYNE-------EYDYNNWMSRSFGGAQRFGRMGNGPP 475
                  |.|||                 :|.|       |.:.::|..|.......:.....|||
 Frog   643 EERWRMEMRNRDSSDQATFFQSSTVQFWRYEEDMYWRRMEEEQHHWDDRRRVPEGGYPHGPPGPP 707

  Fly   476 PHFGMMPG--------GNVRRPESTDDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDAL 532
            ...|:.||        ..:|||:|:|||:.:.:||.|||.|||||.:|:|||.||||||||||::
 Frog   708 GLLGVRPGMPPQPQGPSPLRRPDSSDDRYVMTKHAAIYPTEEELQAVQKIVSLTERALKLVSDSM 772

  Fly   533 AEQPSDAGAANKKDKAEKPSEKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDN 597
            |:|  |.....:.|..::||::                     |.||||:|||.|||||||.||.
 Frog   773 ADQ--DKSKTKESDDKKEPSKE---------------------RALKGVLRVGVLAKGLLLRGDR 814

  Fly   598 AVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIV---LDESVSVKIT 659
            .|.||:|||||||..||.|:...||.:|..:..:   .|.|..:..|||:|:   ::..:.|.||
 Frog   815 NVSLVLLCAEKPTRALLSRITESLPKQLAVICPE---KYEVSCSLAEAAIILNSCVEPKMQVTIT 876

  Fly   660 LTSPLLRDANPGEAATTDEGEGD-SEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRD 723
            ||||::|:.|..:...|.....| .:.|.|:.||.|||.|||||||||||.||||||::||||||
 Frog   877 LTSPVIREENLRDGDVTPGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRD 941

  Fly   724 LCQRVSSWQSLPQWSLELLVEKVISSAGFPISPGDCMRRIMEALSSGFLI-NGPGLLDPCEKDPT 787
            |||||.:|...|.|:|||||||.|||:..|.||||.:||:.|.:|||.:: .||||||||||||.
 Frog   942 LCQRVPTWSDFPSWALELLVEKAISSSSGPQSPGDALRRVFECISSGIILKGGPGLLDPCEKDPY 1006

  Fly   788 DALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLGMEPLPAM--KFPMRPWRVNRKRRRSSGKAG 850
            |.|..:..|:|||:|.|||..||.:|||||||||||:||..|  :|.:..   ||||||
 Frog  1007 DTLATMNDQQREDITSSAQFALRLLAFRQIYKVLGMDPLSQMNQRFNVHN---NRKRRR------ 1062

  Fly   851 GAPGTETESNDIDETGSDEKVAKKE 875
                   :|:.:|...::.|..||:
 Frog  1063 -------DSDGVDSFEAEGKKDKKD 1080

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_788510.1	ZnF_U1	205..236	CDD:197732	27/30 (90%)
		C2H2 Zn finger	207..229	CDD:275371	19/21 (90%)
		ZnF_U1	252..284	CDD:197732	25/31 (81%)
		C2H2 Zn finger	255..277	CDD:275371	18/21 (86%)
		ZnF_U1	368..396	CDD:197732	24/27 (89%)
		C2H2 Zn finger	368..390	CDD:275371	18/21 (86%)
		DZF	577..829	CDD:128842	145/256 (57%)
zfr	XP_012816329.1	ZnF_U1	331..360	CDD:197732	25/28 (89%)
		C2H2 Zn finger	333..355	CDD:275371	19/21 (90%)
		ZnF_U1	384..413	CDD:197732	25/28 (89%)
		C2H2 Zn finger	384..406	CDD:275371	18/21 (86%)
		ZnF_U1	572..603	CDD:197732	25/30 (83%)
		C2H2 Zn finger	575..597	CDD:275371	18/21 (86%)
		DZF	794..1048	CDD:128842	145/256 (57%)