DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zn72D and ilf3

DIOPT Version :9

Sequence 1:	NP_001261924.1	Gene:	Zn72D / 39764	FlyBaseID:	FBgn0263603	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	XP_012808546.1	Gene:	ilf3 / 448121	XenbaseID:	XB-GENE-494367	Length:	908	Species:	Xenopus tropicalis

Alignment Length:	413	Identity:	178/413 - (43%)
Similarity:	248/413 - (60%)	Gaps:	64/413 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   493 DDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAANKKDKAEKP-SEKDG 556
            ||||.:|:|:.:||.:|||:.:|.:|||||||||.|||.:.:|..|.....::.:.|:| :.::|
Frog    10 DDRHVMAKHSVVYPTQEELEAVQNMVSHTERALKAVSDWIDQQEKDCSGEQEQPEPEEPETTEEG 74

  Fly   557 RDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVL 621
            :|:       :...|.|..|.|:||||||.:||||||.||..:|||:||.:|||..||:|||:.|
Frog    75 KDS-------EGKTGENPTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCRDKPTISLLKRVADNL 132

  Fly   622 PDKLKEVAGDTQVNYRVEVNAEEAALIV---LDESVSVKITLTSPLLRD----ANPGEAATTDEG 679
            ..:.:.|:.|   .|.|..|..||::::   .:..:::.|.|||||:|:    .:.||..|..:
Frog   133 VLQFETVSED---KYEVIQNIREASIVIKNTKEPPLTLNIRLTSPLVREEMEKLSAGETLTVSD- 193

  Fly   680 EGDSEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRDLCQRVSSWQSLPQWSLELLVE 744
              ..:.|.|..||.|||.|||||||||||.||:|||:|||:|||||.||.:|:.|..|.||||.|
Frog   194 --PPDVLDRHKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWEPLRGWPLELLCE 256

  Fly   745 KVISSAGFPISPGDCMRRIMEALSSGFLI-NGPGLLDPCEKDPTDALLELTKQEREDLTVSAQLF 808
            |.|.:|..|:..|:.:||::|.||||.|: :||||.|||||:.:|||..|.:|:|||:|.|||..
Frog   257 KAIGTANRPMGAGEALRRVLECLSSGILMPDGPGLYDPCEKEASDALEHLERQQREDITQSAQHA 321

  Fly   809 LRYIAFRQIYKVLGMEPLPAMKFPMRPWRVNRKRRRSSGKAGGAPGTETESNDID---------- 863
            ||..||.|::|||||:|||. |.|.:                    |:.|:..||
Frog   322 LRLAAFGQLHKVLGMDPLPT-KIPKK--------------------TKVETPTIDYTVQIPPSTT 365

  Fly   864 -----------ETGSDEKVAKKE 875
                       |.|.|:..:||:
Frog   366 YAMPALKRPMEEDGEDKSPSKKK 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732
		C2H2 Zn finger	207..229	CDD:275371
		ZnF_U1	252..284	CDD:197732
		C2H2 Zn finger	255..277	CDD:275371
		ZnF_U1	368..396	CDD:197732
		C2H2 Zn finger	368..390	CDD:275371
		DZF	577..829	CDD:128842	134/259 (52%)
ilf3	XP_012808546.1	DZF	88..342	CDD:128842	134/260 (52%)
		DSRM_ILF3_rpt1	399..471	CDD:380739
		DSRM_ILF3_rpt2	516..587	CDD:380741
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	264	1.000	Domainoid score	I1878
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276114at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45762
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020