DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zn72D and ilf2

DIOPT Version :9

Sequence 1:	NP_001261924.1	Gene:	Zn72D / 39764	FlyBaseID:	FBgn0263603	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	NP_998401.1	Gene:	ilf2 / 406517	ZFINID:	ZDB-GENE-040426-2345	Length:	387	Species:	Danio rerio

Alignment Length:	310	Identity:	86/310 - (27%)
Similarity:	142/310 - (45%)	Gaps:	30/310 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   525 LKLVSDALAEQPSDAGAANKKDKAEKPSEKDGRDNQIFSFQKDADN----GGNVVRILKGVMRVG 585
            :|..||..|.  |:......:|.:..|||:....:.:.......||    .||....::.|.:||
Zfish    44 VKPASDETAF--SECLLKRNQDLSPTPSEQASILSLVTKINNVIDNLIVAPGNFEVQIEEVRQVG 106

  Fly   586 YLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIVL 650
            ...||.:..|.|..:|||:....||   |:.|| .|.:|:.|.......:..:.:...|....:.
Zfish   107 SYKKGTMTAGHNVADLVVILKILPT---LEAVA-ALGNKVVETLRTQDPSEVLSMLTNETGFEIS 167

  Fly   651 DESVSVKITLTS--PLLRDANPGEAATTDEGEGDSEFLPREPCLRALADLRHAKWFQARATGLQS 713
            ....:|||.:|:  |.||..:|       |...|.:.|.     .|||.:|||:||:..|:  ||
Zfish   168 SADATVKILITTVPPNLRKLDP-------ELHLDIKVLQ-----SALAAIRHARWFEENAS--QS 218

  Fly   714 CVMV-IRILRDLCQRVSSWQSLPQWSLELLVEKVISS--AGFPISPGDCMRRIMEALSSG-FLIN 774
            .|.| ||:|:|:..|...::.|..|.|:||....:.:  :..|:......||.::.|::| ||..
Zfish   219 TVKVLIRLLKDIRVRFPGFEPLTPWILDLLGHSAVMNHPSRQPLPLNVAYRRCLQMLAAGLFLPG 283

  Fly   775 GPGLLDPCEKDPTDALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLGME 824
            ..|:.||||.........:|.::::.:..:||..:|.::.....|:||:|
Zfish   284 SVGITDPCESGNFRVHTVMTLEQQDMVCFTAQTLVRVLSHGGYRKILGLE 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732
		C2H2 Zn finger	207..229	CDD:275371
		ZnF_U1	252..284	CDD:197732
		C2H2 Zn finger	255..277	CDD:275371
		ZnF_U1	368..396	CDD:197732
		C2H2 Zn finger	368..390	CDD:275371
		DZF	577..829	CDD:128842	73/254 (29%)
ilf2	NP_998401.1	DZF	98..338	CDD:128842	73/254 (29%)
ilf2	NP_998401.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	352..387
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3792
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810