DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zn72D and tarbp2

DIOPT Version :9

Sequence 1:	NP_001261924.1	Gene:	Zn72D / 39764	FlyBaseID:	FBgn0263603	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	NP_956291.1	Gene:	tarbp2 / 336141	ZFINID:	ZDB-GENE-030131-8085	Length:	346	Species:	Danio rerio

Alignment Length:	280	Identity:	55/280 - (19%)
Similarity:	82/280 - (29%)	Gaps:	107/280 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 NGGANNWYQ--RKMGATIPGATAIR---------GMRP-----KAPPRPQQLHY---CEVCKISC 214
            ||..|:.|.  .:|.|..||.|.|.         |..|     ||..:..|.::   ..|..|:|
Zfish     9 NGKRNSGYTSIEQMLAVNPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVSVGDINC 73

  Fly   215 AGPQTYREHLEGQKHKKREASLKM-----------------------------------SASANS 244
            .|   :....:..|||..||:|||                                   |:|...
Zfish    74 TG---HGPSKKAAKHKAAEAALKMLKGGMLGGIGGNGMEGDGFVGIEMEGECPQSEMKSSSSTQQ 135

  Fly   245 A------------------------TQNRGNNYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQ 285
            |                        ||..|..:..|. .:||             :.::.|::..
Zfish   136 AECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEF-TMTC-------------RVERFVEIGS 186

  Fly   286 KLGKPIPSEE--PKKMGKINFVPAAAGGAGVAKTEGGANESDAAGDLDDNLDDSLGENTDNIKPV 348
            ...|.:....  .|.:.:|:.||.....:..|:.|.........|.|:......||...|:::..
Zfish   187 GTSKKLAKRNAAAKMLSRIHDVPVDMRSSHEAEAEDDTFNMQIGGRLEGGKSKGLGCTWDSLRNS 251

  Fly   349 GGEYIEEVKDEEGKILSFNC 368
            .||          |||...|
Zfish   252 AGE----------KILQLRC 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732	9/33 (27%)
		C2H2 Zn finger	207..229	CDD:275371	4/21 (19%)
		ZnF_U1	252..284	CDD:197732	4/31 (13%)
		C2H2 Zn finger	255..277	CDD:275371	3/21 (14%)
		ZnF_U1	368..396	CDD:197732	1/1 (100%)
		C2H2 Zn finger	368..390	CDD:275371	1/1 (100%)
		DZF	577..829	CDD:128842
tarbp2	NP_956291.1	DSRM	31..>79	CDD:214634	10/50 (20%)
		DSRM	139..202	CDD:238007	9/76 (12%)
		Staufen_C	<278..325	CDD:293091
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930