Protein Alignment Zn72D and Zfr2

DIOPT Version :10

• Sequence 1: NP_788510.1
• Gene: Zn72D / 39764
• FlyBaseID: FBgn0263603
• Length: 884
• Species: Drosophila melanogaster
• Sequence 2: XP_038936366.1
• Gene: Zfr2 / 314639
• RGDID: 1304737
• Length: 842
• Species: Rattus norvegicus
• Alignment Length: 979
• Identity: 358/979 - (36%)
• Similarity: 484/979 - (49%)
• Gaps: 235/979 - (24%)

  Fly     1 MANNNYAGFNYGGTQYNTGQVSYPAVTNATYANAAAYQNAAVAAGQGGYGGAAGAGAGATSGPGA 65
            ||.::.:|...|.:..:..|   |:.|.:..|..|:|...:....:    .........||.|.|
  Rat     1 MAASSSSGLAQGASPSSDTQ---PSSTLSLPATGASYTVPSTPRMK----STVSLALAPTSQPPA 58

  Fly    66 --GGYGGYGDYRSAMQYDATKTFYQQSPASYNAS-GSTASVSKTHY--------SAPPVKNQVKG 119
              ||.        .:.|..::....|.|.|.:.| |...:.:.||.        .|...:...:.
  Rat    59 PRGGV--------TVGYSCSQPHPSQGPTSNSRSRGPVPTTASTHQEDGHSCREKATKSRTDSRE 115

  Fly   120 KMDKSNGGPKPPSSAPPAGNNYSGYDTALYNAASMYVAQQHQGNPNQKPNGGANNWYQRKMGATI 184
            :..:|...|.|.|.:|.:.:                |:....|.|...|      |........:
  Rat   116 RPARSLSRPGPSSRSPDSDS----------------VSPDSWGGPVLGP------WDPTFTSDAL 158

  Fly   185 PGATAIRGMRPKAPPRPQQLHYCEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNR 249
            |...  |..:|||.|||..:||||||::|||||||||:|||||||:|::|:.:      :.||..
  Rat   159 PFLD--RLPKPKAGPRPPSMHYCEVCRVSCAGPQTYRDHLEGQKHRKKQAAQR------TRTQPS 215

  Fly   250 G-----NNYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKLGKPIPSE-EPKKM--------- 299
            |     .:.||.||.|:|||.||||||:|||:||||.|||.:|||||||| .|:.:
  Rat   216 GGPRGSQSLHCGLCAVSCTGADAYAAHMRGARHQKVFKLHTRLGKPIPSEPTPRSVTYTRGSDST 280

  Fly   300 ------------------GKINFVPAAAGGAGVAK-------------------------TEGGA 321
                              |:    ||.|.|...::                         |.||:
  Rat   281 PETSVKHEAHARHSSHTQGR----PAPAKGPAASRKGSPELQTVHSWPGDRRPSHCKAEATRGGS 341

  Fly   322 NE-SDAAGDLDDNLDDSLGENTDNIKPVGGEYIEEVKDEEGKILSFNCKLCDCKFNDPNAKEMHM 385
            .| |..:||.:               |||.||:|:|..||||::.|.||||:|.|||.||::||:
  Rat   342 GEASGISGDTE---------------PVGTEYVEQVCSEEGKVIRFRCKLCECSFNDRNARDMHL 391

  Fly   386 KGRRHRLQYKRKVQPDLVVDFKPT-PRQRRLAEARANRAMMSSHRGGDDHDGGYWEEQRNRQYNE 449
            .||||||||::||.|.|.|..:|: |.||.||:....:...:..|   ..|...|..:..:|  |
  Rat   392 TGRRHRLQYRKKVDPTLPVATRPSGPMQRVLAKRLQRQRQQTQAR---LEDAQRWNSELRQQ--E 451

  Fly   450 EYDYNNWMSRSFGGAQRFGRMGNGPP-PHF-GMMPGG--------------------NVRRPEST 492
            |:                .|....|| |.. ..:||.                    :.|||||:
  Rat   452 EH----------------SRQPEEPPQPQVEEQLPGSPTWALPAPTTRPGMASPRRQSGRRPESS 500

  Fly   493 DDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAANKKDKAEKPSEKDGR 557
            ||||.:.:||.|||.|||||.||..||||||||:||||.|||:.|..|..     ...|.
  Rat   501 DDRHVMYKHASIYPTEEELQAIQTAVSHTERALRLVSDTLAEESSQQGTL-----VSPPP----- 555

  Fly   558 DNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVLP 622
                              |:||||:|||.|||||:|.||::|:|.:||::|||..||||:...||
  Rat   556 ------------------RMLKGVVRVGILAKGLVLRGDHSVQLTLLCSKKPTHSLLQRIKQELP 602

  Fly   623 DKLKEVAGDTQVNYRVEVNAEEAALIVL----DESVSVKITLTSPLLRDANPGEAATTDEGEGDS 683
            .:|..||.|     :.||:::..|.||:    :..|.|.::.||||:|:....:....|......
  Rat   603 RELSIVAED-----KYEVSSDHDANIVISACVEPGVKVTVSATSPLMREDPSVKQELQDSLSDPE 662

  Fly   684 EFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRDLCQRVSSWQSLPQWSLELLVEKVIS 748
            :.|.||.||..||.|||||||||||:|||.||:|||:|||||:.:..|.:||.|::|||||||:|
  Rat   663 DILDRERCLETLAALRHAKWFQARASGLQPCVIVIRVLRDLCRCLPPWGALPAWAMELLVEKVLS 727

  Fly   749 SAGFPISPGDCMRRIMEALSSGFLI-NGPGLLDPCEKDPTDALLELTKQEREDLTVSAQLFLRYI 812
            ||..|:||||.|||::|.:::|.|: :||||.|||||.|.|||..:|.|:|||||.|||..||.:
  Rat   728 SAPRPLSPGDAMRRVLEYVATGALLTDGPGLQDPCEKGPQDALEPMTPQQREDLTASAQHALRLV 792

  Fly   813 AFRQIYKVLGMEPLPAMKFPMRPWRVNRKRRRSSGKAGGAPGTETESNDIDETGSDEKVAKKEGV 877
            |||||:|||.||.||    |...:.. |||.|.:.:.              :.|:.|:...::|.
  Rat   793 AFRQIHKVLHMEHLP----PRTRFGA-RKRMREASQT--------------QEGARERKRGRQGT 838

  Fly   878 GGTP 881
            .|.|
  Rat   839 AGLP 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_788510.1	ZnF_U1	205..236	CDD:197732	24/30 (80%)
		C2H2 Zn finger	207..229	CDD:275371	18/21 (86%)
		ZnF_U1	252..284	CDD:197732	22/31 (71%)
		C2H2 Zn finger	255..277	CDD:275371	16/21 (76%)
		ZnF_U1	368..396	CDD:197732	20/27 (74%)
		C2H2 Zn finger	368..390	CDD:275371	14/21 (67%)
		DZF	577..829	CDD:128842	138/256 (54%)
Zfr2	XP_038936366.1	PHA03247	<20..310	CDD:223021	104/338 (31%)
		ZnF_U1	177..204	CDD:197732	22/26 (85%)
		C2H2 Zn finger	179..225	CDD:275371	25/51 (49%)
		ZnF_U1	224..255	CDD:197732	22/30 (73%)
		C2H2 Zn finger	226..248	CDD:275371	16/21 (76%)
		ZnF_U1	371..402	CDD:197732	21/30 (70%)
		C2H2 Zn finger	374..396	CDD:275371	14/21 (67%)
		DZF	558..809	CDD:295427	138/259 (53%)