DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zn72D and Prkra

DIOPT Version :9

Sequence 1:	NP_001261924.1	Gene:	Zn72D / 39764	FlyBaseID:	FBgn0263603	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	NP_001019951.1	Gene:	Prkra / 311130	RGDID:	1306707	Length:	313	Species:	Rattus norvegicus

Alignment Length:	102	Identity:	27/102 - (26%)
Similarity:	40/102 - (39%)	Gaps:	33/102 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 PNQKPNGGANNWYQRKMGATIPGATAIR-----GMRPKAPPRPQQLHYCE--------------- 208
            |.|:.:.|  .:...||....||.|.|:     |.:.|..|    ::.||
  Rat    12 PLQREDSG--TFSLGKMITAKPGKTPIQVLHEYGTKTKNIP----VYECERSDVQVHVPTFTFRV 70

  Fly   209 -VCKISCAGPQTYREHLEGQKHKKREAS---LKMSAS 241
             |..|:|.|..|.::.   .||:..||:   ||.:||
  Rat    71 TVGDITCTGEGTSKKL---AKHRAAEAAINILKANAS 104

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732	11/49 (22%)
		C2H2 Zn finger	207..229	CDD:275371	7/37 (19%)
		ZnF_U1	252..284	CDD:197732
		C2H2 Zn finger	255..277	CDD:275371
		ZnF_U1	368..396	CDD:197732
		C2H2 Zn finger	368..390	CDD:275371
		DZF	577..829	CDD:128842
Prkra	NP_001019951.1	Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	1..103		25/99 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		3/9 (33%)
		DSRM	35..100	CDD:214634	15/71 (21%)
		Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	102..195		2/3 (67%)
		DSRM	126..192	CDD:238007
		Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	195..313
		DSRM	241..307	CDD:214634
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352098
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930