DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zn72D and Ilf2

DIOPT Version :9

Sequence 1:	NP_001261924.1	Gene:	Zn72D / 39764	FlyBaseID:	FBgn0263603	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	XP_038958228.1	Gene:	Ilf2 / 310612	RGDID:	1305734	Length:	511	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	102/392 - (26%)
Similarity:	163/392 - (41%)	Gaps:	58/392 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 NGPPPHFGMMPGGNVRRPESTD----DRHAIA------------------RHAEIYPKEEELQTI 514
            ||..||..:: |..:.||....    .||.:|                  .:.|:. ..|:|:..
  Rat    82 NGGKPHRDIL-GSRITRPTGIKPLCLPRHILAYDWLAQSLLGIVIGSISLAYNELL-MMEKLKGF 144

  Fly   515 QRIVSH-------TERALKLVSDALAEQP-SDAGAANKKDKAEKPSEKDGRDNQIFSFQKDADN- 570
            :..|.|       .|.|...|..|..|.. |:|.....:|.|...:|:....:.:.......||
  Rat   145 RPFVPHIPFDFYLCEMAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNL 209

  Fly   571 ----GGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGD 631
                |...|:| :.|.:||...||.:..|.|..:|||:....||...:..:.|.:.:.|:  |.|
  Rat   210 IVAPGTFEVQI-EEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLR--AQD 271

  Fly   632 TQVNYRVEVNAEEAALIVLDESVSVKITLTSPLLRDANPGEAATTDEGEGDSEFLPREPCLRALA 696
            ......:..|.....:...|.:|.:.||...|.||..:|       |...|.:.|.     .|||
  Rat   272 PSEVLTMLTNETGFEISSSDATVKILITTVPPNLRKLDP-------ELHLDIKVLQ-----SALA 324

  Fly   697 DLRHAKWFQARATGLQSCVMV-IRILRDLCQRVSSWQSLPQWSLELLVEKVI--SSAGFPISPGD 758
            .:|||:||:..|:  ||.|.| ||:|:||..|...::.|..|.|:||....:  :....|::...
  Rat   325 AIRHARWFEENAS--QSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNV 387

  Fly   759 CMRRIMEALSSG-FLINGPGLLDPCEKDPTDALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLG 822
            ..||.::.|::| ||....|:.||||.........:|.::::.:..:||..:|.::.....|:||
  Rat   388 AYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILG 452

  Fly   823 ME 824
            .|
  Rat   453 QE 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732
		C2H2 Zn finger	207..229	CDD:275371
		ZnF_U1	252..284	CDD:197732
		C2H2 Zn finger	255..277	CDD:275371
		ZnF_U1	368..396	CDD:197732
		C2H2 Zn finger	368..390	CDD:275371
		DZF	577..829	CDD:128842	73/252 (29%)
Ilf2	XP_038958228.1	DZF	219..459	CDD:128842	73/253 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910