Protein Alignment Zn72D and Adarb1

DIOPT Version :10

• Sequence 1: NP_788510.1
• Gene: Zn72D / 39764
• FlyBaseID: FBgn0263603
• Length: 884
• Species: Drosophila melanogaster
• Sequence 2: XP_006256337.1
• Gene: Adarb1 / 25367
• RGDID: 2033
• Length: 775
• Species: Rattus norvegicus
• Alignment Length: 759
• Identity: 143/759 - (18%)
• Similarity: 231/759 - (30%)
• Gaps: 268/759 - (35%)

  Fly    13 GTQY----NTGQVSYPAVTNATYANAAAYQNAAVAAGQGGYGGAAGAGAGATSGPGAGGYGGYGD 73
            |.||    .||.|..|....:...|...::                 |:|.|.
  Rat   156 GLQYMLLSQTGPVHAPLFVMSVEVNGQVFE-----------------GSGPTK------------ 191

  Fly    74 YRSAMQYDATK---TFYQQSPAS--YNASGSTASVSKTHYSAPPVKNQVKGKMDKSNGGPKPPSS 133
             :.|..:.|.|   :|.|...||  :.|.|.|.||: |.:::    :|........||...|..|
  Rat   192 -KKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVN-TDFTS----DQADFPDTLFNGFETPDKS 250

  Fly   134 APPAGNNYSGYDTALYNAASMYVAQQHQGNPNQKPNGGANNWYQRKMGATIPGATAIRGMRPKAP 198
            .||                 .||..  .|:.:...:|..:      :.|:...|:..:...|..|
  Rat   251 EPP-----------------FYVGS--NGDDSFSSSGDVS------LSASPVPASLTQPPLPIPP 290

  Fly   199 PRPQQLHYCEVCKISCAGPQTYREHL--EGQKHKKREASLKMSASANSATQNRGNNYHCELCDVT 261
            |.|.......|..::...|....:.|  .|:.|.|   |..||...:      |..:.
  Rat   291 PFPPPSGKNPVMILNELRPGLKYDFLSESGESHAK---SFVMSVVVD------GQFFE------- 339

  Fly   262 CTGTDAYAAHVRGAKH--QKVVKLHQKLGKPIPSEEP--------------------KKMGKI-- 302
            .:|.:...|..|.|:.  ..|..||.   ...||.:|                    ..:||.
  Rat   340 GSGRNKKLAKARAAQSALATVFNLHL---DQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSD 401

  Fly   303 ---NFVPAAAGG---AGVAKTEGGANESDAAGDLDDNLDDSLGENTDNIKPVGGEYIEEVKDEEG 361
               ||....|..   :||..|.|        .|:.|....|:...|   |.:.|||:.:
  Rat   402 LTDNFSSPHARRKVLSGVVMTTG--------TDVKDAKVISVSTGT---KCINGEYMSD------ 449

  Fly   362 KILSFNCKLCDCKFNDPNAKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMS 426
            :.|:.|    ||        ...:..||..|:: ...|.:|.::.|         |.:.......
  Rat   450 RGLALN----DC--------HAEIISRRSLLRF-LYAQLELYLNNK---------EDQKKSIFQK 492

  Fly   427 SHRGGDDHDGGYWEEQRNRQYNEEYDYNNWMSRS-FGGAQRFGRMGNGPPPHFGMMPGGNVRRPE 490
            |.|||             .:..:...::.::|.| .|.|:.|.       ||..::.|
  Rat   493 SERGG-------------FRLKDTVQFHLYISTSPCGDARIFS-------PHEPVLEG------- 530

  Fly   491 STDDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAANKKDKAEKPSEKD 555
            ...|.|.:...|:.:|..:....::..:...|..:.:.|:| :.|..|.....::......|:|.
  Rat   531 MAPDSHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNA-SIQTWDGVLQGERLLTMSCSDKI 594

  Fly   556 GRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANV 620
            .|.| :...|      |.::.|....:....:..|.|.|||:.           :..:.||::|:
  Rat   595 ARWN-VVGIQ------GALLSIFVEPIYFSSIILGSLYHGDHL-----------SRAMYQRISNI 641

  Fly   621 LPDKLKEVAGDTQVNYRVEVNAEEAALIVLDESVSVKITLTSPLLRDAN------PGEA------ 673
                                           |.:....||..|||...:      ||:|
  Rat   642 -------------------------------EDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVN 675

  Fly   674 ------------ATTDEGEGDSEFLPREPCLRALADLRHAKWFQ 705
                        |||.:   |....|...|..||    :.:|.:
  Rat   676 WTVGDTAIEVINATTGK---DELGRPSRLCKHAL----YCRWMR 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_788510.1	ZnF_U1	205..236	CDD:197732	6/32 (19%)
		C2H2 Zn finger	207..229	CDD:275371	4/23 (17%)
		ZnF_U1	252..284	CDD:197732	5/33 (15%)
		C2H2 Zn finger	255..277	CDD:275371	4/21 (19%)
		ZnF_U1	368..396	CDD:197732	5/27 (19%)
		C2H2 Zn finger	368..390	CDD:275371	3/21 (14%)
		DZF	577..829	CDD:128842	27/153 (18%)
Adarb1	XP_006256337.1	DSRM_RED1_rpt1	139..210	CDD:380724	16/83 (19%)
		DSRM_RED1_rpt2	296..365	CDD:380727	16/84 (19%)
		ADEAMc	386..772	CDD:214718	82/450 (18%)