DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zn72D and Ilf3

DIOPT Version :9

Sequence 1:	NP_001261924.1	Gene:	Zn72D / 39764	FlyBaseID:	FBgn0263603	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	XP_011240705.1	Gene:	Ilf3 / 16201	MGIID:	1339973	Length:	916	Species:	Mus musculus

Alignment Length:	399	Identity:	171/399 - (42%)
Similarity:	244/399 - (61%)	Gaps:	37/399 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   493 DDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQP---SDAGAANKKDKAEKPSEK 554
            ||||.:|:|:.:||.:|||:.:|.:|||||||||.|||.:.||.   |:...|...|.......|
Mouse    28 DDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGNSELSEAENMDTPPDDESK 92

  Fly   555 DGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVAN 619
            :|...|         ...::.|.|:||||||.:||||||.||..:|||:||.||||:.||.:||:
Mouse    93 EGAGEQ---------KAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKVAD 148

  Fly   620 VLPDKLKEVAGDTQVNYRVEVNAEEAALIV---LDESVSVKITLTSPLLRD----ANPGEAATTD 677
            .|..:|..|   |:..|.:..:.::||:::   .:..:|:.|.||||::|:    ...||..:.:
Mouse   149 NLAIQLTTV---TEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVN 210

  Fly   678 EGEGDSEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRDLCQRVSSWQSLPQWSLELL 742
            :   ..:.|.|:.||.|||.|||||||||||.||:|||:|||:|||||.||.:|..|..|.||||
Mouse   211 D---PPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLELL 272

  Fly   743 VEKVISSAGFPISPGDCMRRIMEALSSGFLI-NGPGLLDPCEKDPTDALLELTKQEREDLTVSAQ 806
            .||.|.:|..|:..|:.:||::|.|:||.:: :|.|:.|||||:.|||:..|.:|:|||:|.|||
Mouse   273 CEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQ 337

  Fly   807 LFLRYIAFRQIYKVLGMEPLPAMKFPMRPWRVNRKRRRSSGKAGGAPGTETES-----NDIDETG 866
            ..||..||.|::|||||:|||: |.|.:|     |...........|.:.|.:     ..::|.|
Mouse   338 HALRLAAFGQLHKVLGMDPLPS-KMPKKP-----KNENPVDYTVQIPPSTTYAITPMKRPMEEDG 396

  Fly   867 SDEKVAKKE 875
            .::..:||:
Mouse   397 EEKSPSKKK 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732
		C2H2 Zn finger	207..229	CDD:275371
		ZnF_U1	252..284	CDD:197732
		C2H2 Zn finger	255..277	CDD:275371
		ZnF_U1	368..396	CDD:197732
		C2H2 Zn finger	368..390	CDD:275371
		DZF	577..829	CDD:128842	128/259 (49%)
Ilf3	XP_011240705.1	DZF	106..360	CDD:128842	128/260 (49%)
		DSRM_ILF3_rpt1	416..488	CDD:380739
		DSRM_ILF3_rpt2	538..609	CDD:380741
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848528
Domainoid	1	1.000	268	1.000	Domainoid score	I1847
eggNOG	1	0.900	-	-		E1_KOG3792
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276114at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45762
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850