Protein Alignment Zn72D and Zn72D

DIOPT Version :10

• Sequence 1: NP_788510.1
• Gene: Zn72D / 39764
• FlyBaseID: FBgn0263603
• Length: 884
• Species: Drosophila melanogaster
• Sequence 2: XP_061502322.1
• Gene: Zn72D / 1281222
• VectorBaseID: AGAMI1_012625
• Length: 1068
• Species: Anopheles gambiae
• Alignment Length: 1008
• Identity: 481/1008 - (47%)
• Similarity: 592/1008 - (58%)
• Gaps: 197/1008 - (19%)

  Fly    13 GTQYNTGQVSYPAVTNATYANAAAYQNAAVAAGQGGYGGAAGAGAGATSGPGAGGYGGYGDYRSA 77
            ||.|.|.|..| ||..|....|..|..|........|..||..|..||:...|....|||  |:.
Mosquito   102 GTAYPTTQTGY-AVAPAPTPAAPTYGTARPTGYDQAYQPAATPGTYATTATAATYDYGYG--RTT 163

  Fly    78 MQYDATKTFYQQ---------SPASYNASGSTASV-------SKTHYSAPPVKNQVKGKMDKSNG 126
            ..||.:||:|||         :|..|:|.|:...|       ..|.|:..|    .:|.:..:..
Mosquito   164 QTYDTSKTYYQQAAGATAGYSTPTGYDAGGTAPKVIAGFQPGQATAYAPQP----ARGSLPPAKA 224

  Fly   127 G--------------PKP---------------------PSSAPPAG----NN---YSGYDTALY 149
            |              |:|                     |.||..||    ||   |.|||.|||
Mosquito   225 GQQYQQTTQHQPAAAPQPQAYVPTQPTGYSQTVTTVHTTPKSAAVAGTVVPNNSATYPGYDAALY 289

  Fly   150 NAASMYVA-QQHQGNPNQK-----PNGG--------------------ANNWYQRKMG-ATIPGA 187
            .|.:|||. ||.|..||.|     |.||                    ..:|...|.| ..:.|.
Mosquito   290 GATTMYVTQQQQQPPPNTKAPANVPGGGGAMPGAPGGAAVITSGPVPAGGSWSNYKSGKGGMQGH 354

  Fly   188 TAIRGMRP----KAPPRPQQLHYCEVCKISCAGPQTYREHLEGQKHKKREASLKMSAS-ANSATQ 247
            ....|..|    |..|:|..:|||:|||||||||||||||||||||||||..||.:|. ..:|..
Mosquito   355 GHGHGGGPYKARKPAPKPMLIHYCDVCKISCAGPQTYREHLEGQKHKKRELLLKQAAEPGGTAPA 419

  Fly   248 NRGNNYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKLGKPIPSEEP-------KKMGKINFV 305
            ...|:.|||||.|||||.|||||||||||||||||||.|||||||:.:|       ||.......
Mosquito   420 RPPNSLHCELCGVTCTGNDAYAAHVRGAKHQKVVKLHTKLGKPIPACDPTPNADGEKKESAAGES 484

  Fly   306 PAAAGGAGVAKTEGGANESDAAGDLDDNLDDSLGENTDNIKPVGGEYIEEVKDEEGKILSFNCKL 370
            ..|||||.     .|.|.:...|.:.....:|   :.::::|||.|:|||:||::||::||:|||
Mosquito   485 SEAAGGAA-----AGVNNAGGGGGVGGGGAES---SEESVRPVGSEFIEEIKDDDGKLVSFSCKL 541

  Fly   371 CDCKFNDPNAKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMSSHRGGDDHD 435
            |:|||||||||||||||||||||||:|||||||||.|||.:|:::|||||:|..|...
Mosquito   542 CECKFNDPNAKEMHMKGRRHRLQYKKKVQPDLVVDIKPTVKQKKIAEARAHRQAMQEE------- 599

  Fly   436 GGYWEEQR--NRQYNEEYDYNNWMSRSFGGAQRFGRMGNGPPPHFGMMPGGNVRRPESTDDRHAI 498
              :|..:|  :.:..||:           |.:.|||     .|.|||:||   |||||:||||.:
Mosquito   600 --FWNRRRMADAEMEEEH-----------GMRTFGR-----HPFFGMLPG---RRPESSDDRHVV 643

  Fly   499 ARHAEIYPKEEELQTIQRIVSHTERALKLVSDAL------------AEQPSDAGAA--------- 542
            ||||||||||||||||||||||||||||||||.:            |.||:.|.||
Mosquito   644 ARHAEIYPKEEELQTIQRIVSHTERALKLVSDVMTSGGGCATGSVPAAQPAPAAAAPAAAGAPSE 708

  Fly   543 ------NKKDK-----AEKPS----EKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLL 592
                  |.:.|     :::||    ..:|:.||:.||.|:.:  |..:|:||||||||.||||||
Mosquito   709 QKTEPTNDQSKEQEIQSQQPSTTAGNGNGKANQMISFHKETE--GTTIRLLKGVMRVGLLAKGLL 771

  Fly   593 LHGDNAVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIVLDESVSVK 657
            |||||.|:||||||||||:.||:|||..||.:||::|.|.:  |.|.:...|.|::|.|.:::||
Mosquito   772 LHGDNCVQLVVLCAEKPTTSLLKRVATELPIQLKKIAEDHR--YTVTMAPVEGAVLVTDGTITVK 834

  Fly   658 ITLTSPLLRDANPGEAATTDEGEGDSEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILR 722
            |:|||||||:||...|  ....:...:.|||||||:|||.|||||||||||||||||||::||:|
Mosquito   835 ISLTSPLLREANAPSA--EQAAQNTEDLLPREPCLQALAALRHAKWFQARATGLQSCVMIMRIMR 897

  Fly   723 DLCQRVSSWQSLPQWSLELLVEKVISSAGFPISPGDCMRRIMEALSSGFLINGPGLLDPCEKDPT 787
            |||||:..|..:.||::|||:||:|||||..::||:|:||:|||:||..|||||||||||||:|.
Mosquito   898 DLCQRIPIWSHISQWAMELLLEKIISSAGEVLTPGECLRRVMEAISSAILINGPGLLDPCEKEPE 962

  Fly   788 DALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLGMEPLPAMKFP-MRPWRVNRKRRRSSGKAGG 851
            |.|..|:||:|||:|||||:|||.|||||||||||:||||..||. .|.||.|||||||.
Mosquito   963 DTLAGLSKQQREDITVSAQMFLRCIAFRQIYKVLGIEPLPPPKFAGSRNWRFNRKRRRSG----- 1022

  Fly   852 APGTETESNDIDETGSDEKVAKKEGVGGTPAST 884
                 ||.||.:..||  |:.||:..|.:.||:
Mosquito  1023 -----TEGNDSEADGS--KMLKKDESGASSASS 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_788510.1	ZnF_U1	205..236	CDD:197732	28/30 (93%)
		C2H2 Zn finger	207..229	CDD:275371	20/21 (95%)
		ZnF_U1	252..284	CDD:197732	27/31 (87%)
		C2H2 Zn finger	255..277	CDD:275371	19/21 (90%)
		ZnF_U1	368..396	CDD:197732	26/27 (96%)
		C2H2 Zn finger	368..390	CDD:275371	20/21 (95%)
		DZF	577..829	CDD:128842	165/251 (66%)
Zn72D	XP_061502322.1	None