Protein Alignment Zn72D and ADARB1

DIOPT Version :9

• Sequence 1: NP_001261924.1
• Gene: Zn72D / 39764
• FlyBaseID: FBgn0263603
• Length: 884
• Species: Drosophila melanogaster
• Sequence 2: XP_016883731.1
• Gene: ADARB1 / 104
• HGNCID: 226
• Length: 790
• Species: Homo sapiens
• Alignment Length: 829
• Identity: 152/829 - (18%)
• Similarity: 241/829 - (29%)
• Gaps: 298/829 - (35%)

  Fly    17 NTGQVSYPAVTNATYANAAAYQNAAVAAGQGGYGGAAGAGAGATSGPGAGGYGGYGDYR------ 75
            |....|.....|....|.:....:....|:|......|.|......|...|..|:..||
Human    57 NMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRK 121

  Fly    76 ---------SAMQYDATKTFYQQSPAS--------------------YNASGSTASVSKTHYSAP 111
                     :.||.:..|...|.:..|                    :..||.|...:|.|.:..
Human   122 TPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEK 186

  Fly   112 PVKNQVK-----------GK---------MDKS-------NGGPKPPSSAPPAGNNYSGYDTALY 149
            .:::.|:           |:         .|::       ||...|..:.||
Human   187 ALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPP------------- 238

  Fly   150 NAASMYVAQQHQGNPNQKPNGGANNWYQRKMGATIPGATAIRGMRPKAPPRPQQLHYCEVCKISC 214
                .||..  .|:.:...:|..:      :.|:...|:..:...|..||.|.......|..::.
Human   239 ----FYVGS--NGDDSFSSSGDLS------LSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNE 291

  Fly   215 AGPQTYREHL--EGQKHKKREASLKMSASANSATQNRGNNYHCELCDVTCTGTDAYAAHVRGAKH 277
            ..|....:.|  .|:.|.|   |..||...:      |..:.       .:|.:...|..|.|:.
Human   292 LRPGLKYDFLSESGESHAK---SFVMSVVVD------GQFFE-------GSGRNKKLAKARAAQS 340

  Fly   278 --QKVVKLH---QKLGKPIPSEE-----PK------------KMGKI--NFVPAAAGG---AGVA 315
              ..:..||   ....:|||||.     |:            |.|.:  ||....|..   |||.
Human   341 ALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVV 405

  Fly   316 KTEGGANESDAAGDLDDNLDDSLGENTDNIKPVGGEYIEE----VKDEEGKILSFNCKLCDCKF- 375
            .|.|        .|:.|....|:...|   |.:.|||:.:    :.|...:|:|....|   :|
Human   406 MTTG--------TDVKDAKVISVSTGT---KCINGEYMSDRGLALNDCHAEIISRRSLL---RFL 456

  Fly   376 ----------NDPNAKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMSSHRG 430
                      .|...:.:..|..|...:.|..||..|.:...|      ..:||    :.|.|
Human   457 YTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSP------CGDAR----IFSPH-- 509

  Fly   431 GDDHDGGYWEE--QRNRQYNEEYDYNNWMSRSFGGAQ--RFGRMGNGPP-----PHFGMMPGGNV 486
                     |.  :.:|.|.:            .|.|  ..|.:...||     |......|...
Human   510 ---------EPILEGSRSYTQ------------AGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGT 553

  Fly   487 RRPESTDDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAANKKDKAEKP 551
            ..|.   |||         |..:....::..:...|..:.:.|:| :.|..|.....::......
Human   554 TEPA---DRH---------PNRKARGQLRTKIESGEGTIPVRSNA-SIQTWDGVLQGERLLTMSC 605

  Fly   552 SEKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQR 616
            |:|..|.| :...|      |:::.|....:....:..|.|.|||:.           :..:.||
Human   606 SDKIARWN-VVGIQ------GSLLSIFVEPIYFSSIILGSLYHGDHL-----------SRAMYQR 652

  Fly   617 VANVLPDKLKEVAGDTQVNYRVEVNAEEAALIVLDESVSVKITLTSPLLRDAN------PGEA-- 673
            ::|:                               |.:....||..|||...:      ||:|
Human   653 ISNI-------------------------------EDLPPLYTLNKPLLSGISNAEARQPGKAPN 686

  Fly   674 ----------------ATTDEGE-GDSEFLPREPCLRALADLRHAKWFQ 705
                            |||.:.| |.:..|    |..||    :.:|.:
Human   687 FSVNWTVGDSAIEVINATTGKDELGRASRL----CKHAL----YCRWMR 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732	6/32 (19%)
		C2H2 Zn finger	207..229	CDD:275371	4/23 (17%)
		ZnF_U1	252..284	CDD:197732	4/33 (12%)
		C2H2 Zn finger	255..277	CDD:275371	4/21 (19%)
		ZnF_U1	368..396	CDD:197732	5/38 (13%)
		C2H2 Zn finger	368..390	CDD:275371	4/32 (13%)
		DZF	577..829	CDD:128842	28/154 (18%)
ADARB1	XP_016883731.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158119
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930