DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zn72D and strbp

DIOPT Version :9

Sequence 1:	NP_001261924.1	Gene:	Zn72D / 39764	FlyBaseID:	FBgn0263603	Length:	884	Species:	Drosophila melanogaster
Sequence 2:	XP_012808670.1	Gene:	strbp / 100135229	XenbaseID:	XB-GENE-1005085	Length:	734	Species:	Xenopus tropicalis

Alignment Length:	403	Identity:	171/403 - (42%)
Similarity:	235/403 - (58%)	Gaps:	52/403 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 RPESTDDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAAN-----KKDK 547
            |..:.||||.:|:|:.|||..|||:.:|.:||..|.|||.|||.:.|........|     |::.
Frog    64 RSFANDDRHVMAKHSIIYPSPEELEAVQNMVSTVECALKHVSDWMDEHKCIKKIENEPQITKENT 128

  Fly   548 AEKPSEKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSG 612
            .:.|::::..                  |:|.||||:|.:|||||:..|..:|||::|.|||:..
Frog   129 EDSPAKEESG------------------RVLCGVMRIGLVAKGLLIKDDMDLELVLMCKEKPSES 175

  Fly   613 LLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIV---LDESVSVKITLTSPLLRDA--NPG- 671
            ||..|...||.:::::   |:..|:||...|:|:||:   .:..:::|:.|||||.|:.  .||
Frog   176 LLATVTENLPLQIQKI---TEETYQVEQCVEDASLIIQSSKEPKLTLKVILTSPLFREEEDRPGG 237

  Fly   672 --EAATTDEGEGDSEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRDLCQRVSSWQSL 734
              ..|..|    ..:.|.|:.||.|||.|||||||||||.||:|||:|:|||||||.||.:|..|
Frog   238 VENVAMKD----PPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPAWAQL 298

  Fly   735 PQWSLELLVEKVISSAGFPISPGDCMRRIMEALSSGFLI-NGPGLLDPCEKDPTDALLELTKQER 798
            ..|.|||:.||.|.:...|:..|:.:||::|.|:||.|: .||||.||||::|||||..:|.:||
Frog   299 KGWPLELICEKAIGTCNRPLGAGEALRRVVECLASGILLPGGPGLHDPCEREPTDALAYMTVKER 363

  Fly   799 EDLTVSAQLFLRYIAFRQIYKVLGMEPLPAMK-FPMRPWRVNRKRRRSSGKAGGAPGTETESNDI 862
            ||:|.|||..||.:||.||||||.|:||.:.| ||...|. |..|..||.|           ...
Frog   364 EDITHSAQHALRLLAFGQIYKVLQMDPLLSNKPFPKYSWS-NSDREGSSLK-----------RPF 416

  Fly   863 DETGSDEKVAKKE 875
            |:...|||...|:
Frog   417 DDGSCDEKDPNKK 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zn72D	NP_001261924.1	ZnF_U1	205..236	CDD:197732
		C2H2 Zn finger	207..229	CDD:275371
		ZnF_U1	252..284	CDD:197732
		C2H2 Zn finger	255..277	CDD:275371
		ZnF_U1	368..396	CDD:197732
		C2H2 Zn finger	368..390	CDD:275371
		DZF	577..829	CDD:128842	129/260 (50%)
strbp	XP_012808670.1	DZF	140..393	CDD:128842	129/259 (50%)
		DSRM_STRBP_rpt1	444..527	CDD:380738
		DSRM_ILF3_rpt2	565..634	CDD:380741
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	264	1.000	Domainoid score	I1878
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276114at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010