Protein Alignment IntS9 and CFT2

DIOPT Version :9

• Sequence 1: NP_648838.3
• Gene: IntS9 / 39763
• FlyBaseID: FBgn0036570
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_013216.1
• Gene: CFT2 / 850806
• SGDID: S000004105
• Length: 859
• Species: Saccharomyces cerevisiae
• Alignment Length: 618
• Identity: 136/618 - (22%)
• Similarity: 225/618 - (36%)
• Gaps: 164/618 - (26%)

  Fly    96 EVDVILIS----NYLNMLALPYITENTGF--KGKVYATEPTLQIGRFFLEELVDYIE---VSPKA 151
            |:|||::|    ..|...:|.|....:.|  :.:||||.|.:.:||  :..:..|..   :.|..
Yeast    53 EIDVIILSQPTIECLGAHSLLYYNFTSHFISRIQVYATLPVINLGR--VSTIDSYASAGVIGPYD 115

  Fly   152 CTARLWKEKL-----HLLPSPLSEAFRAKKWRTIFSLKDVQGSLSKVTIMGYDEKLDILGAFIAT 211
             |.:|..|.:     |::|...|:            |.|::.....:|::.|
Yeast   116 -TNKLDLEDIEISFDHIVPLKYSQ------------LVDLRSRYDGLTLLAY------------- 154

  Fly   212 PVSSGYCLGSSNWVLSTAHEKICY-----------VSGSSTLTTHPRPINQSALKHADVLIMTGL 265
              ::|.|.|.|.|.:||..||:.|           ::.:|.|....:|:  |.|.....:|.| |
Yeast   155 --NAGVCPGGSIWCISTYSEKLVYAKRWNHTRDNILNAASILDATGKPL--STLMRPSAIITT-L 214

  Fly   266 TQAPTVNPDTKLGELCMN-VALTIRNNGSALIPCYPSGVVYDLF----ECLTQNLENAGLNNVPM 325
            .:..:..|..|..::..: :...:.::||.:||...||...|||    |.|.::.:......||:
Yeast   215 DRFGSSQPFKKRSKIFKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLFESTKINAHTQVPV 279

  Fly   326 FFISPVADSSLAYSNILAEWLSSA------KQNKVYLPDDPFPHAFYLR---NNKLKHYNHVFSE 381
            ..:|.....:|.|:..:.||||.:      .:|..    .||.....::   .|:|..|..
Yeast   280 LILSYARGRTLTYAKSMLEWLSPSLLKTWENRNNT----SPFEIGSRIKIIAPNELSKYPG---- 336

  Fly   382 GFSKDFRQPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSIIFTEPDF-------PYLQVLAPFQ-- 437
              ||      :.|.........:.:..:   ||:...::|.|:|.|       ..|:::...:
Yeast   337 --SK------ICFVSEVGALINEVIIKV---GNSEKTTLILTKPSFECASSLDKILEIVEQDERN 390

  Fly   438 ----PLAMKAFYCPIDTSLNYQQANKLIKELKPNVLVIPEAYTKPHPSAPNLFIEQPDKK----- 493
                |...|:|.|....|::..:...|.|| :.....:.....|...:...|.:::..||
Yeast   391 WKTFPEDGKSFLCDNYISIDTIKEEPLSKE-ETEAFKVQLKEKKRDRNKKILLVKRESKKLANGN 454

  Fly   494 -IITFKCGEIIRLPLKRKLDRIYITSELAQKISPKEVAAG--------VTFSTLTGVLQVKDKVH 549
             ||....||       |.:....|..|....:.|.:...|        .....|..:|  ||...
Yeast   455 AIIDDTNGE-------RAMRNQDILVENVNGVPPIDHIMGGDEDDDEEEENDNLLNLL--KDNSE 510

  Fly   550 --------------CIQPCADSVKDETISSNSAPTKEDVLKNVKYEYGSIDVDAVMKKLAQDGFS 600
                          .|||.|.| |.:....|.|..|:|       :||:: ||..|  ...|...
Yeast   511 KSAAKKNTEVPVDIIIQPSAAS-KHKMFPFNPAKIKKD-------DYGTV-VDFTM--FLPDDSD 564

  Fly   601 NI-----KLDRTGGALTLNLVNEDTVIKFEDNE 628
            |:     |.....||.|.:.|||      |||:
Yeast   565 NVNQNSRKRPLKDGAKTTSPVNE------EDNK 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS9	NP_648838.3	metallo-hydrolase-like_MBL-fold	1..264	CDD:304873	44/192 (23%)
		Beta-Casp	304..428	CDD:214983	29/143 (20%)
CFT2	NP_013216.1	Lactamase_B_6	19..211	CDD:406948	43/189 (23%)
		Beta-Casp	254..372	CDD:214983	28/136 (21%)
		CPSF100_C	732..856	CDD:404222

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810