Protein Alignment IntS9 and ints9

DIOPT Version :9

• Sequence 1: NP_648838.3
• Gene: IntS9 / 39763
• FlyBaseID: FBgn0036570
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001070738.1
• Gene: ints9 / 768124
• ZFINID: ZDB-GENE-061013-129
• Length: 658
• Species: Danio rerio
• Alignment Length: 663
• Identity: 340/663 - (51%)
• Similarity: 451/663 - (68%)
• Gaps: 18/663 - (2%)

  Fly     1 MRLYCLSGDLAKPCYIITFKGLRIMLDCGLTEQTVLNFLPLPFVQSLKWSNLPNFVPSRDHDPQM 65
            |:||||||....||.::.||...|||||||.....|.|||||.|.|.:.|.||.:| |:|....:
Zfish     1 MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDTTAALYFLPLPLVHSPRLSKLPGWV-SKDGAINL 64

  Fly    66 DGELKDCCGRVFVDSTPEFNLPMDKMLDFSEVDVILISNYLNMLALPYITENTGFKGKVYATEPT 130
            :.|||:|.|||||||.|||.||..::||.|.:||||||||..|:|||||||:|||.|.|||||||
Zfish    65 EKELKECSGRVFVDSQPEFCLPEKELLDLSTIDVILISNYHCMMALPYITEHTGFTGTVYATEPT 129

  Fly   131 LQIGRFFLEELVDYIEVSPKACTARLWKEK--LHLLPSPLSEAFRAKKWRTIFSLKDVQGSLSKV 193
            |||||..:||||.::|..|||..|..||.|  ..|||.||.:|.....|...:||::|..:||||
Zfish   130 LQIGRLLMEELVAFMERVPKAHAASCWKNKEIQRLLPGPLKDAVEVWSWSKCYSLQEVNSALSKV 194

  Fly   194 TIMGYDEKLDILGAFIATPVSSGYCLGSSNWVLSTAHEKICYVSGSSTLTTHPRPINQSALKHAD 258
            .::||.:|:::.||...||:||||.||||||::.:.:||:.||||||.|||||:|:.||:||::|
Zfish   195 QLVGYSQKVELFGAVQVTPLSSGYSLGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMEQSSLKNSD 259

  Fly   259 VLIMTGLTQAPTVNPDTKLGELCMNVALTIRNNGSALIPCYPSGVVYDLFECLTQNLENAGLNNV 323
            |||:|||||.||.|||..|||.|.|:|:|:|..|:.|:|||.|||:|||.|||.|.:::|.|...
Zfish   260 VLILTGLTQIPTANPDGMLGEFCSNLAMTVRAGGNVLVPCYSSGVIYDLLECLYQFMDSANLGTT 324

  Fly   324 PMFFISPVADSSLAYSNILAEWLSSAKQNKVYLPDDPFPHAFYLRNNKLKHYNHVFSEGFSKDFR 388
            |.:||||||:|||.:|.|.||||...||:|||||:.|||||..::.||||||..:..: ||.:||
Zfish   325 PFYFISPVANSSLEFSQIFAEWLCQNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGD-FSSEFR 388

  Fly   389 QPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSIIFTEPDFPYLQVLAPFQPLAMKAFYCPIDTSLN 453
            ||||||.|||||||||.|||:|:||.:..|:||||||||.||..|||:||||||..||||||.||
Zfish   389 QPCVVFTGHPSLRFGDVVHFMELWGKSSLNTIIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLN 453

  Fly   454 YQQANKLIKELKPNVLVIPEAYTKPHPSAP---NLFIEQPDKKIITFKCGEIIRLPLKRKLDRIY 515
            :.|.:||:|:::|..:|.||.||:|.||.|   :|.:|.....:...:| .::|||.:|:.:||:
Zfish   454 FHQVSKLLKDIQPLHVVCPEPYTQPPPSQPHRSDLMLELQPPPMAYRRC-SVLRLPFRRRYERIH 517

  Fly   516 ITSELAQKISPKEVAAGVTFSTLTGVLQVKDKVHCIQ------PCADSVKDETISSNSAPTKEDV 574
            :..|||:.:.|.||.|||:.:|::.|||.||..|.:|      |.|.|.|.:.:...  |.::
Zfish   518 LLPELAKSLVPSEVKAGVSVATVSAVLQSKDNKHVLQPVPKVAPVAPSKKRKRVLEE--PPEQ-- 578

  Fly   575 LKNVKYEYGSIDVDAVMKKLAQDGFSNIKLDRTGGALTLNLVNEDTVIKFEDNETHIICGGKPTT 639
            ||......|::.::..:..|.::|...:|::.|.....|:|..||.:|:.||:.|||||......
Zfish   579 LKPKTLLSGAVPLEPFLATLHKNGIMEVKVEETADGHILHLQAEDVLIQLEDDATHIICDNNEPL 643

  Fly   640 RLKLRDTIMKCLQ 652
            |..|||.:::.||
Zfish   644 RTALRDLVLRFLQ 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS9	NP_648838.3	metallo-hydrolase-like_MBL-fold	1..264	CDD:304873	148/264 (56%)
		Beta-Casp	304..428	CDD:214983	76/123 (62%)
ints9	NP_001070738.1	Int9-like_MBL-fold	1..265	CDD:293852	148/264 (56%)
		Beta-Casp	307..425	CDD:214983	72/118 (61%)
		HTH_LacI	532..>573	CDD:143331	15/40 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593941
Domainoid	1	1.000	166	1.000	Domainoid score	I3846
eggNOG	1	0.900	-	-		E1_COG1236
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10096
Inparanoid	1	1.050	667	1.000	Inparanoid score	I723
OMA	1	1.010	-	-		QHG54690
OrthoDB	1	1.010	-	-		D194350at33208
OrthoFinder	1	1.000	-	-		FOG0005526
OrthoInspector	1	1.000	-	-		oto39931
orthoMCL	1	0.900	-	-		OOG6_104387
Panther	1	1.100	-	-	LDO	PTHR46094
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4208
SonicParanoid	1	1.000	-	-		X3947
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800