Protein Alignment IntS9 and IntS11

DIOPT Version :9

• Sequence 1: NP_648838.3
• Gene: IntS9 / 39763
• FlyBaseID: FBgn0036570
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_651721.1
• Gene: IntS11 / 43506
• FlyBaseID: FBgn0039691
• Length: 597
• Species: Drosophila melanogaster
• Alignment Length: 685
• Identity: 138/685 - (20%)
• Similarity: 247/685 - (36%)
• Gaps: 182/685 - (26%)

  Fly     9 DLAKPCYIITFKGLRIMLDCGLTEQTVLNFLPLPFVQSLKWSNLPNFVPSRDHDPQMDGELKDCC 73
            |:.:.|.:::..|..||||||:               .:.:::...|
  Fly    14 DVGRSCLLLSMGGKNIMLDCGM---------------HMGYNDERRF------------------ 45

  Fly    74 GRVFVDSTPEFNLPMDKMLDFSEVDVILISNYL--NMLALPYITENTGFKGKVYATEPTLQIGRF 136
                    |:|:..:.:....|.:|.::||::.  :..||||::|..|:.|.:|.|.||..|...
  Fly    46 --------PDFSYIVPEGPITSHIDCVIISHFHLDHCGALPYMSEIVGYTGPIYMTHPTKAIAPI 102

  Fly   137 FLEELVDYIEVSPKACTARLWKEKLHLLPSPLSEAFRAKKWRTIFSLKDVQGSLSKVTI---MGY 198
            .||::                 .|:.:.....|..|      |...:||....:..||:   |..
  Fly   103 LLEDM-----------------RKVAVERKGESNFF------TTQMIKDCMKKVIPVTLHQSMMV 144

  Fly   199 DEKLDILGAFIATPVSSGYCLGSSNWVLSTAHEKICYVSGSSTLTTHPRPINQSAL-KHADVLIM 262
            |..|:|...:      :|:.||::.:.:....:.:.| :|...:|. .|.:..:.: |....|::
  Fly   145 DTDLEIKAYY------AGHVLGAAMFWIKVGSQSVVY-TGDYNMTP-DRHLGAAWIDKCRPDLLI 201

  Fly   263 TGLTQAPTVNPDTKLGE--LCMNVALTIRNNGSALIPCYPSGVVYDLFECLTQNLENAGLNNVPM 325
            :..|.|.|:....:..|  ....|...:...|..|||.:..|...:|...|....|...| ..|:
  Fly   202 SESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLIPVFALGRAQELCILLETYWERMNL-KYPI 265

  Fly   326 FFISPVADSSLAYSNILAEWLSSAKQNKVYLPDDPFPHAFYLRNNKLKHYNHVFSEGFSK---DF 387
            :|...:.:.:..|..:...| ::.|..|.::..:.|            .:.|:  :.|.|   |.
  Fly   266 YFALGLTEKANTYYKMFITW-TNQKIRKTFVHRNMF------------DFKHI--KPFDKAYIDN 315

  Fly   388 RQPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSIIF-----------------TEPDFPYLQVLAP 435
            ....|||.....|..|.::...:.|..|.||.:|.                 .:.:|...||:
  Fly   316 PGAMVVFATPGMLHAGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEFENRQVV-- 378

  Fly   436 FQPLAMKAFYCPIDTSLNYQQANKLIKELKP-NVLVIPEAYTKPHPSAPNL-FIEQPDKKIITFK 498
              .:.|...|.......:.:...:||:..:| ||:::       |..|..: |:....|.....:
  Fly   379 --EVKMAVEYMSFSAHADAKGIMQLIQNCEPKNVMLV-------HGEAGKMKFLRSKIKDEFNLE 434

  Fly   499 C-----GE--IIRLPLKRKLD------RIYITSELAQKISPKEVAAGVTFSTLTGVLQVKDKVHC 550
            .     ||  :|..|:|..:|      :....|..||...||.      ...:.|||.:||....
  Fly   435 TYMPANGETCVISTPVKIPVDASVSLLKAEARSYNAQPPDPKR------RRLIHGVLVMKDNRIM 493

  Fly   551 IQPCADSVKDETIS------------SNSAPT--KEDVLKNV-----------KYEYGSIDVDAV 590
            :|...|::|:..|:            .:|.|.  ..:.||.:           ..|.|||.:::|
  Fly   494 LQNLTDALKEIGINRHVMRFTSKVKMDDSGPVIRTSERLKTLLEEKLAGWTVTMQENGSIAIESV 558

  Fly   591 MKKLAQD----GFSNIKLDRTG-----GALTLNLV 616
            ..|:.:|    ...||.:..|.     ||..||::
  Fly   559 EVKVEEDEKDPKQKNILISWTNQDEDIGAYILNVL 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS9	NP_648838.3	metallo-hydrolase-like_MBL-fold	1..264	CDD:304873	51/260 (20%)
		Beta-Casp	304..428	CDD:214983	25/143 (17%)
IntS11	NP_651721.1	YSH1	4..446	CDD:224157	102/530 (19%)
		INTS11-like_MBL-fold	6..204	CDD:293849	51/261 (20%)
		Beta-Casp	245..363	CDD:214983	25/133 (19%)
		RMMBL	376..416	CDD:284853	10/50 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440174
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740