Protein Alignment IntS9 and Cpsf73

DIOPT Version :9

• Sequence 1: NP_648838.3
• Gene: IntS9 / 39763
• FlyBaseID: FBgn0036570
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_650738.1
• Gene: Cpsf73 / 42240
• FlyBaseID: FBgn0261065
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 697
• Identity: 143/697 - (20%)
• Similarity: 257/697 - (36%)
• Gaps: 221/697 - (31%)

  Fly     9 DLAKPCYIITFKGLRIMLDCGLTEQTVLNFLPLPFVQSLKWSNLPNFVPSRDHDPQMDGELKDCC 73
            ::.:.|.::.|||.:||||||:                               .|.:.|
  Fly    28 EVGRSCIMLEFKGKKIMLDCGI-------------------------------HPGLSG------ 55

  Fly    74 GRVFVDSTPEFNLPMDKMLDFSEVDVILISNYL--NMLALPYITENTGFKGKVYATEPTLQIGRF 136
                :|:     ||...:::..|:|::.||::.  :..|||:....|.|||:.:.|..|..|.|:
  Fly    56 ----MDA-----LPYVDLIEADEIDLLFISHFHLDHCGALPWFLMKTSFKGRCFMTHATKAIYRW 111

  Fly   137 FLEELVDYIEVSPKACTARLWKEKLHLLPSPLSEAFRAKKWRTIFSLKDVQGSLSKVTIMGYDEK 201
            .|.   |||::|..:....|:.|                        .|::.|:.|:..:.:.|:
  Fly   112 MLS---DYIKISNISTEQMLYTE------------------------ADLEASMEKIETINFHEE 149

  Fly   202 LDILG----AFIATPVSSGYCLGSSNWVLSTAHEKICYVSGSSTLTTHPRPINQSALKHADVLIM 262
            .|::|    |:||     |:.||::.:::..|..||.|....|              :..|..:|
  Fly   150 RDVMGVRFCAYIA-----GHVLGAAMFMIEIAGIKILYTGDFS--------------RQEDRHLM 195

  Fly   263 TGLTQAPTVNPDTKLGELCMN-----------------VALTIRNNGSALIPCYPSGVVYDLFEC 310
            .  .:.|.:.||..:.|....                 |...::..|..|||.:..|...:|...
  Fly   196 A--AEVPPMKPDVLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQELLLI 258

  Fly   311 LTQN-LENAGLNNVPMFFISPVADSSLAYSNILAEWLSSAKQNKVYLPDDPFPHAFYLRNNKLKH 374
            |.:. .:|..|:.:|:::.|.:|...:|........::...:.::.: ::||   .:...:.||.
  Fly   259 LDEFWSQNPDLHEIPIYYASSLAKKCMAVYQTYINAMNDRIRRQIAV-NNPF---VFRHISNLKG 319

  Fly   375 YNHVFSEGFSKDFRQPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSII--------------FTEP 425
            .:|....|       |||:......::.|.:....|.|..:|.|.:|              .:||
  Fly   320 IDHFEDIG-------PCVIMASPGMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKAVLSEP 377

  Fly   426 DFPYLQVLAPFQ-PLAMKAFYCPIDTSLNYQQANKLIKELKPNVLVIPEAYTKPHPSAPNLFIEQ 489
            :  .:..|:..: ||.|...|.......:|||.::.|:.|||..:|:...             ||
  Fly   378 E--EITTLSGQKLPLNMSVDYISFSAHTDYQQTSEFIRLLKPTHVVLVHG-------------EQ 427

  Fly   490 PDKKIITFKCGEIIRLPLKRKLDR------------------IYITSELAQKI----SPKEVAAG 532
            .:.        ..::|.|:|:.:.                  :|...|...|:    :.|....|
  Fly   428 NEM--------SRLKLALQREYEADASTDIKFYNPRNTHAVDLYFRGEKTAKVMGSLAAKNSEVG 484

  Fly   533 VTFSTLTGVLQVKD-KVHCIQPCADSVK--DETIS----------SNSAPTKEDVLKNVKYEYGS 584
               |.|:|||..:| |.|.:.| :|..|  |.::|          .:|..|.|.:|..:  ..|.
  Fly   485 ---SKLSGVLVKRDFKYHLLAP-SDLGKYTDMSMSVVTQRQSIPWGSSLSTLELLLDRI--GAGC 543

  Fly   585 IDVDAVMKKLAQDGFSNIKLDRTGGALTLNLVNEDTVIKFEDNETHI 631
            ::|....:||           |..|.:.|.:  |..:|..|...||:
  Fly   544 VEVLEAERKL-----------RVFGCIELTV--EQKIIVMEWQATHV 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS9	NP_648838.3	metallo-hydrolase-like_MBL-fold	1..264	CDD:304873	56/260 (22%)
		Beta-Casp	304..428	CDD:214983	25/138 (18%)
Cpsf73	NP_650738.1	YSH1	18..456	CDD:224157	109/555 (20%)
		CPSF3-like_MBL-fold	18..211	CDD:293850	59/276 (21%)
		Beta-Casp	252..373	CDD:214983	23/131 (18%)
		RMMBL	386..426	CDD:284853	12/52 (23%)
		CPSF73-100_C	483..683	CDD:215023	30/114 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440176
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740