Protein Alignment IntS9 and Cpsf2

DIOPT Version :10

• Sequence 1: NP_648838.3
• Gene: IntS9 / 39763
• FlyBaseID: FBgn0036570
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: XP_063117833.1
• Gene: Cpsf2 / 299256
• RGDID: 1309687
• Length: 800
• Species: Rattus norvegicus
• Alignment Length: 755
• Identity: 154/755 - (20%)
• Similarity: 262/755 - (34%)
• Gaps: 243/755 - (32%)

  Fly     1 MRLYCLSG--DLAKPCYIITFKGLRIMLDCGLTEQTVLNFLPLPFVQSLKWSNLPNFVPSRDHDP 63
            ::|..|||  :.:..||::.....|.:||||..|.     ..:..:.||           |.|
  Rat    23 IKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEH-----FSVDIIDSL-----------RKH-- 69

  Fly    64 QMDGELKDCCGRVFVDSTPEFNLPMDKMLDFSEVDVILIS--NYLNMLALPYITENTGFKGKVYA 126
                                          ..::|.:|:|  :.|::.|||:.....|....:||
  Rat    70 ------------------------------VHQIDAVLLSHPDPLHLGALPFAVGKLGLNCAIYA 104

  Fly   127 TEPTLQIGRFFLEELVDYIEVSPKACTARLWKEKLHLLPSPLSEAFRAKKWRTIFSLKDVQGSLS 191
            |.|..::|:.|:.:|.                :..|     .:|.|      |:|:|.||..:..
  Rat   105 TIPVYKMGQMFMYDLY----------------QSRH-----NTEDF------TLFTLDDVDAAFD 142

  Fly   192 KVTIMGYDEKLDILG---AFIATPVSSGYCLGSSNW-VLSTAHEKICYVSGSSTLTTHPRPINQS 252
            |:..:.:.:.:::.|   ....||:.:|:.:|.:.| ::....|:|.|....:    |.|.|:.:
  Rat   143 KIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFN----HKREIHLN 203

  Fly   253 A----LKHADVLIMTGLTQAPTVNPDTKL--GELCMNVALTIRNNGSALIPCYPSGVVYDLFECL 311
            .    :.....|::|....|..|.|..|.  .:|..||..|:|.:|:.||....:|.|.:|.:.|
  Rat   204 GCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLL 268

  Fly   312 TQ--NLENAGLNNVPMFFISPVADSSLAYSNILAEWLSSAKQNKVYLPDDPFPHAFYLRNNKLKH 374
            .|  ..::|||....:..::.|:.:.:.:|....||:|           |.....|..:.|....
  Rat   269 DQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMS-----------DKLMRCFEDKRNNPFQ 322

  Fly   375 YNHV-FSEGFSKDFR--QPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSIIFTEPDFPYLQVLAPF 436
            :.|: ...|.|...|  .|.||....|.|..|.:......|..:|.||||.|....|  ..||.|
  Rat   323 FRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTP--GTLARF 385

  Fly   437 QPLAMKAFYCPID------TSL--------------NYQQANKLIKELKPNV------------- 468
            .          ||      |.:              .|.:..||.||....:
  Rat   386 L----------IDNPSEKVTEIELRKRVKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDE 440

  Fly   469 ------LVIPEAYTKPHP-------SAPNLFIEQ----------PDKKIITFKCGEIIRLPLKRK 510
                  :..|.|:...|.       |....|.:|          |:::|...:.||||: |....
  Rat   441 SDVEEDVDQPTAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIK-PEDFL 504

  Fly   511 LDRIYITSELAQKISPKEVAAGVTFS----------------TLTGVLQVKDKVHCI----QPCA 555
            :..:..|.|...|:.     :|:|..                :.|..:::|.:|..|    :...
  Rat   505 VPELQATEEEKSKLE-----SGLTNGEEPMDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDG 564

  Fly   556 DSVKD--------ETISSNSAPTKEDVLKNVKYEYGSIDVDAVMKKLAQDGFSNIKLDRTGGALT 612
            ||:|.        :.|..:..|.....|......:|..|:...|.||.:      .:|.|
  Rat   565 DSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHE------TVDAT----- 618

  Fly   613 LNLVNEDTVIKFEDNETHIICGGKPTTRLKLRDTIMKCLQ 652
                          :||||.       :::|:|:::..||
  Rat   619 --------------SETHIY-------QVRLKDSLVSSLQ 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS9	NP_648838.3	metallo-hydrolase-like_MBL-fold	1..264	CDD:451500	53/274 (19%)
		Beta-Casp	304..428	CDD:214983	32/128 (25%)
Cpsf2	XP_063117833.1	None