DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment IntS9 and Dclre1a

DIOPT Version :9

Sequence 1:	NP_648838.3	Gene:	IntS9 / 39763	FlyBaseID:	FBgn0036570	Length:	654	Species:	Drosophila melanogaster
Sequence 2:	NP_001099671.1	Gene:	Dclre1a / 292127	RGDID:	1306156	Length:	1026	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	63/322 - (19%)
Similarity:	104/322 - (32%)	Gaps:	111/322 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 AFYLRNNKLKHYNHVFSEGFSKDFRQPCVVFCGH-------PSLR---------------FGDAV 406
            |::|.:....||     .|.||||.:|  ::|..       ..||               ..|.|
  Rat   713 AYFLTHFHSDHY-----AGLSKDFTRP--IYCSEITGSLLKKKLRVQEQYIHQLPMDTECIVDGV 770

  Fly   407 HFIEMWGNN-----------PNNSIIFTEPDF---PYLQ--VLA--PFQPLAMKAFYC-PIDTSL 452
            ..:.:..|:           ||.::.....||   |.::  :||  ....|.:...|| |..|..
  Rat   771 KVVLLDANHCPGATMILFQLPNGAVTLHTGDFRADPSMERSLLASRKVHTLFLDTTYCSPEYTFP 835

  Fly   453 NYQQA-----NKLIK--ELKPNVLVIPEAY----------------------TKPHPSAPNLFIE 488
            :.|:|     |...:  .|.|..|::...|                      .:.:.:...|.|.
  Rat   836 SQQEAIQFAINTAFEAVTLNPRALIVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIP 900

  Fly   489 QPDKKIITFKCGEIIRL-------------PLKR---KLDRIY------------ITS--ELAQK 523
            :....|.|..|..::.|             .||:   |.|:|.            |||  ::..:
  Rat   901 EVSSLITTDMCNSLVHLLPMMQINFKGLQNHLKKCGGKFDQILAFRPTGWTHSNNITSIADITPQ 965

  Fly   524 ISPKEVAAGVTFSTLTGVLQVKDKVHCIQP--CADSVKDETISSNSAPTKEDVLKNVKYEYG 583
            ........|:.:|..:..|::|..|..::|  ...:|...|..|.:  |.|...|..:.|.|
  Rat   966 TKGNIAIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTFQSRN--TMEKYFKEWRLEAG 1025

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
IntS9	NP_648838.3	metallo-hydrolase-like_MBL-fold	1..264	CDD:304873
IntS9	NP_648838.3	Beta-Casp	304..428	CDD:214983	20/99 (20%)
Dclre1a	NP_001099671.1	Ustilago_mating	<7..115	CDD:114448
		metallo-hydrolase-like_MBL-fold	675..830	CDD:304873	26/123 (21%)
		DRMBL	900..1005	CDD:284854	19/104 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900