Protein Alignment IntS9 and Ints9

DIOPT Version :10

• Sequence 1: NP_648838.3
• Gene: IntS9 / 39763
• FlyBaseID: FBgn0036570
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_001389188.1
• Gene: Ints9 / 290322
• RGDID: 1311539
• Length: 658
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 346/666 - (51%)
• Similarity: 472/666 - (70%)
• Gaps: 20/666 - (3%)

  Fly     1 MRLYCLSGDLAKPCYIITFKGLRIMLDCGLTEQTVLNFLPLPFVQSLKWSNLPNFVPSRDHDPQM 65
            |:||||||....||.::.||...|||||||...:.|||||||.|||.:.||||.: ..:|.:..:
  Rat     1 MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGW-SLKDGNAFL 64

  Fly    66 DGELKDCCGRVFVDSTPEFNLPMDKMLDFSEVDVILISNYLNMLALPYITENTGFKGKVYATEPT 130
            |.|||:|.|.|||||.|||.||..:::|.|.|||||||||..|:|||||||:|||.|.|||||||
  Rat    65 DKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPT 129

  Fly   131 LQIGRFFLEELVDYIEVSPKACTARLWKEK--LHLLPSPLSEAFRAKKWRTIFSLKDVQGSLSKV 193
            :||||..:||||::||..|||.:|.|||.|  ..||||||.:|.....||..:::::|..:|||:
  Rat   130 MQIGRLLMEELVNFIERVPKAQSASLWKNKEIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKI 194

  Fly   194 TIMGYDEKLDILGAFIATPVSSGYCLGSSNWVLSTAHEKICYVSGSSTLTTHPRPINQSALKHAD 258
            .::||.:|:::.||...||:||||.||||||::.:.:||:.||||||.|||||:|::|::||::|
  Rat   195 QLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSD 259

  Fly   259 VLIMTGLTQAPTVNPDTKLGELCMNVALTIRNNGSALIPCYPSGVVYDLFECLTQNLENAGLNNV 323
            |||:|||||.||.|||..:||.|.|:|||:||.|:.|:|||||||:|||.|||.|.:::|||:|:
  Rat   260 VLILTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNI 324

  Fly   324 PMFFISPVADSSLAYSNILAEWLSSAKQNKVYLPDDPFPHAFYLRNNKLKHYNHVFSEGFSKDFR 388
            |.:||||||:|||.:|.|.||||...||:|||||:.|||||..::.||||||..:..: ||.|||
  Rat   325 PFYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYRSIHGD-FSHDFR 388

  Fly   389 QPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSIIFTEPDFPYLQVLAPFQPLAMKAFYCPIDTSLN 453
            ||||:|.|||||||||.|||:|:||.:..|::|||||||.||:.|||:||||||..||||||.||
  Rat   389 QPCVLFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLN 453

  Fly   454 YQQANKLIKELKPNVLVIPEAYTKPHPSAP---NLFIE-QPDKKIITFKCGEIIRLPLKRKLDRI 514
            :.|.:||:||::|..:|.||.||:|.|:..   :|.|: ||  ..::::..|::.||.||:.::|
  Rat   454 FIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQP--PAMSYRRAEVLALPFKRRYEKI 516

  Fly   515 YITSELAQKISPKEVAAGVTFSTLTGVLQVKDKVHCIQP------CADSVKDETISSNSAPTKED 573
            .|..|||..:.|.|:..|::.:|::.||..||..|.:||      ...|.|.:.:|.:...:|
  Rat   517 EIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHVLQPPPKPTQPTSSKKRKRVSEDVPDSK-- 579

  Fly   574 VLKNVKYEYGSIDVDAVMKKLAQDGFSNIKLDRTGGALTLNLVNEDTVIKFEDNETHIICGGKPT 638
            |||.:.  .|||.|:..::.|.:.|||:||::.|.....:.|...:|:|:.|::.|||||....|
  Rat   580 VLKPLL--SGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDET 642

  Fly   639 TRLKLRDTIMKCLQSF 654
            .|::|||.:::.||.|
  Rat   643 LRVRLRDLVLRFLQKF 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS9	NP_648838.3	metallo-hydrolase-like_MBL-fold	1..264	CDD:451500	148/264 (56%)
		Beta-Casp	304..428	CDD:214983	77/123 (63%)
Ints9	NP_001389188.1	Int9-like_MBL-fold	1..265	CDD:293852	148/264 (56%)
		Beta-Casp	307..425	CDD:214983	73/118 (62%)