Protein Alignment IntS9 and ints-9

DIOPT Version :9

• Sequence 1: NP_648838.3
• Gene: IntS9 / 39763
• FlyBaseID: FBgn0036570
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_504953.1
• Gene: ints-9 / 179142
• WormBaseID: WBGene00017608
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 192/676 - (28%)
• Similarity: 350/676 - (51%)
• Gaps: 95/676 - (14%)

  Fly    12 KPCYIITFKGLRIMLDCGLTEQTVLNFLP----LPFV-QSLKWSNLPNFVPSRDHDPQMDGELKD 71
            |||:::.:...||::|      |.::|.|    ||.| ||.:..|.|  :..:...|.    ||:
 Worm    12 KPCFLLEWPNARILMD------TPIDFTPFFSFLPHVYQSPRIKNAP--IAKKFQIPY----LKE 64

  Fly    72 CCGRVFVDSTPE-FNLPMDKMLDFSEVDVILISNYLNMLALPYITENTGFKGKVYATEPTLQIGR 135
            ...||:|:|.|| |::..| ||....:|.||:|||.:.:.||:.||.:||.||:|.||...|.|:
 Worm    65 LGNRVYVESPPEIFHVSTD-MLKMDTIDAILVSNYESFVGLPFYTEGSGFSGKIYVTEIAYQYGK 128

  Fly   136 FFLEELVDY---IEVSPKACTARLWK--EKLHLLPSPLSEAFRAKKWRTIFSLKDVQGSLSKVTI 195
            ..:||::::   |||.|   :.:.||  |.....|:|..:  ...:||..::..|:...|:||..
 Worm   129 LLMEEMLEFISRIEVLP---SDKKWKREEFCGKFPNPPFQ--NPVEWRPYYTTTDMHSCLAKVIT 188

  Fly   196 MGYDEKLDILGAFIATPVSSGYCLGSSNWVLSTAHEKICYVSGSSTLTTHPRPINQSALKHADVL 260
            :.:::.:|:....: |||.||:..||:.|.:.|.:|:..|:|.|:...|..:.:..:.|:..|.:
 Worm   189 LSFNQTIDLFRIKV-TPVVSGHTYGSAYWTIKTENEQFAYLSASNPSATDVKLMETAPLRAVDHI 252

  Fly   261 IMTGLTQAPTVNPDTKLGELCMNVALTI----RNNGSALIPCYPSGVVYDLFECLTQNLENAGLN 321
            ::|.|::.    .||...|:..::..||    :.:||.|:|..|.|.::::.|.::..:...  |
 Worm   253 LVTSLSRL----VDTTAKEMGYSLIKTITDVLKKHGSVLLPICPVGPIFEMIEAVSDIITTT--N 311

  Fly   322 NVPM----FFISPVADSSLAYSNILAEWLSSAKQNKVYLPDDPFPHAFYLRNNKLKHYNHVFSEG 382
            .:|:    :||||||.|::|.::|.|||:|.::||.||||::|:.|:..:::.::|.|:.::. .
 Worm   312 GIPLDTPIYFISPVAKSAIAMASISAEWMSESRQNAVYLPEEPYSHSNLIKSGRVKIYDSLYG-S 375

  Fly   383 FSKDFRQPCVVFCGHPSLRFGDAVHFIEMWGNNPNNSIIFTEPDFPYLQVLAPFQPLAMKAFYCP 447
            |||:|:.|||:|..|.|||.|||.|.:|:.|::|.|::|.|:||.|...|..||:.|.:|....|
 Worm   376 FSKEFKTPCVIFASHASLRIGDAAHMVEVLGSDPKNAVIVTDPDLPCEDVREPFRNLPIKFINIP 440

  Fly   448 IDTSLNYQQANKLIKELKPNVLVIPEAYTKPHPSAPNLFIEQPDKKI-------ITF-KCGEIIR 504
            :|..:::....:|:.:.||..::...:||:|       .|.:||.:|       |.: :|.::.:
 Worm   441 MDFRMDFASLERLLADAKPKYVLCSSSYTRP-------MIRRPDMQINYEKVWPIEYDECVQLSK 498

  Fly   505 LPL-KRKLDRIYITSELAQKISPKEVAAGVTFSTLTGVLQVKDKVHCIQPCADSVKDETISSNSA 568
            |.. |:||..:.:..|:.:.:..|               |...|...:...|..:..........
 Worm   499 LSRNKQKLVTVAVHPEVVKNLKFK---------------QHPSKKLAVASIACHLSAYNDDFKLV 548

  Fly   569 PTKEDVLKNVKYEYGSIDVDAVMKKLAQDGFSNIKLDRTGGALTLNLVNEDTVIKFEDNETHIIC 633
            |.|   :|..:.:||.|.:..|:|.|....:...::::.          ::||::.::.|..|..
 Worm   549 PAK---VKIARRKYGRITLAKVLKALRDKNWDAKEVEKP----------DETVLEIDELEAKITV 600

  Fly   634 GGKPT-TRL-----KLRDTIMKCLQS 653
            ....| |::     :.|:.|::.::|
 Worm   601 KNDGTGTKISSNNQENREKILEMIRS 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS9	NP_648838.3	metallo-hydrolase-like_MBL-fold	1..264	CDD:304873	82/262 (31%)
		Beta-Casp	304..428	CDD:214983	50/127 (39%)
ints-9	NP_504953.1	metallo-hydrolase-like_MBL-fold	1..256	CDD:390040	82/262 (31%)
		Beta-Casp	298..416	CDD:214983	47/120 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165895
Domainoid	1	1.000	113	1.000	Domainoid score	I3869
eggNOG	1	0.900	-	-		E1_COG1236
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10096
Inparanoid	1	1.050	282	1.000	Inparanoid score	I1748
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54690
OrthoDB	1	1.010	-	-		D194350at33208
OrthoFinder	1	1.000	-	-		FOG0005526
OrthoInspector	1	1.000	-	-		oto20746
orthoMCL	1	0.900	-	-		OOG6_104387
Panther	1	1.100	-	-	LDO	PTHR46094
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4208
SonicParanoid	1	1.000	-	-		X3947
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800