DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment IleRS-m and AT4G10320

DIOPT Version :9

Sequence 1:	NP_648837.2	Gene:	IleRS-m / 39762	FlyBaseID:	FBgn0036569	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_192770.2	Gene:	AT4G10320 / 826624	AraportID:	AT4G10320	Length:	1190	Species:	Arabidopsis thaliana

Alignment Length:	892	Identity:	245/892 - (27%)
Similarity:	365/892 - (40%)	Gaps:	234/892 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 REEQERLVLENKIAVSYAYQEQRLAEKGKPTFVLHDGPPYANGQLHMGHAVNKILKDITLRQRVA 110
            |:|::.|....:|.   |::.|....:..|.::.:||||:|.|..|.||.:...:|||..|.:..
plant    14 RQEEDVLSFWTEID---AFKTQLKRTENLPEYIFYDGPPFATGLPHYGHILAGTIKDIVTRYQTM 75

  Fly   111 HGQRVNYIPGWDCHGLPIELKATSTAPGQSAQEIRQKSRAFAWEAIKSQKEEFSSWGI------- 168
            .|..|....||||||||:|            .||.:|..      || :::|....||
plant    76 TGHHVTRRFGWDCHGLPVE------------NEIDRKLN------IK-RRDEVIKMGIDKYNEEC 121

  Fly   169 -------LANWQK-----------DNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWSPSS 215
                   :|.|:|           .|.|.|....|:.:...:|..|:||.||||..|.:.:|...
plant   122 RSIVTRYVAEWEKVITRCGRWIDFKNDYKTMDLPFMESVWWVFSQLWEKNLVYRGFKVMPYSTGC 186

  Fly   216 RTALAEAELEYDANHI-SPSVYVRFALNPSSFDVKDKQIYALV-WTTTPWTLPSNQAICYNASLE 278
            :|.|:..|...:...: .|.:.|.|.:      :.|:...|.| |||||||||||.|:|.||...
plant   187 KTPLSNFEAGQNYKEVPDPEIMVTFPV------IGDQDNAAFVAWTTTPWTLPSNLALCVNAKFV 245

  Fly   279 YVIVRLSDRNQDELYLMA----SALMAD--------------FEANTQLK----------CEIVQ 315
            ||.||  ::|..::|::|    |||..|              .:||.:.|          .|:::
plant   246 YVKVR--NKNTGKVYIVAESRLSALPTDKPKAKLSNGPAGDTKKANPKAKGAKPESAADSYEVLE 308

  Fly   316 HLSGELLSKLSYNHPIDKEQSNLPFFD--------------ASHVQDSKGTGLVHTAPAHGPEDF 366
            ..:|..|....|.          |.||              ..:|.|..|||:||.|||.|.:|:
plant   309 KFNGASLVGKKYE----------PLFDYFSDFSSEAFRVVADDYVTDDSGTGIVHCAPAFGEDDY 363

  Fly   367 LVSLTQKIPVK-----CFVNEEGTYTKEAPDFLRGKSVLDQGNSLVLDRIAED-VVHSSKLEHSY 425
            .|.|..||..|     ..|:::|.:|:....| .|:.|.|....::....|:. :|.:....|||
plant   364 RVCLLNKIIKKGENLVVAVDDDGLFTERITHF-SGRYVKDADKDIIEAVKAKGRLVKTGSFTHSY 427

  Fly   426 PIDWRTKKPVIIRASEQWFINTEKLKTPAADALEQVEIYPRANAEASKKALLTQLQKRPYWCISR 490
            |..||:..|:|.||...||:..|:||.....:.||.|..|   .....|.....|:....|.|||
plant   428 PFCWRSDTPLIYRAVPSWFVRVEQLKEKLLKSNEQTEWVP---GYVKDKRFHNWLENARDWAISR 489

  Fly   491 QRAWGVPIPVLYSRESGKVVLNSALIEHLCNLLRKEGSIDFWWVKSVEELVPEHL----LRELHH 551
            .|.||.|:|:..|.:..:||:                      :.|||:|  |.|    :.:||.
plant   490 SRFWGTPLPIWISDDGEEVVI----------------------MDSVEKL--EKLSGVKVFDLHR 530

  Fly   552 EAKD--------------LVKGTDILDIWFDSGSTWSA----------VLGKDKIADLYLEGYDQ 592
            ...|              |.:..|:.|.||:|||...|          :..|:...|...||.||
plant   531 HHIDHITIPSSRGDEFGVLRRVEDVFDCWFESGSMPYAYIHYPFENKELFEKNFPGDFVAEGLDQ 595

  Fly   593 FTGWFQSSLLMSIAARECAPYKALFVHGFTVDEKGYKMSKSLGNVISPKQITKKYGTDALRWWVA 657
            ..|||.:.:::|.|..|...:|.|..:|..:.|.|.||:|.|.|...|.::..:||.||:|.::
plant   596 TRGWFYTLMVLSTALFEKPAFKNLICNGLVLAEDGKKMAKKLRNYPPPLEVIDEYGADAVRLYL- 659

  Fly   658 SHGTQHMSITVSDKLLQQAAENLCKIRGTMRYLK-GVIG-----------------------EKQ 698
                      ::..:::  ||.|       |:.| ||:|                       |.:
plant   660 ----------INSPVVR--AEPL-------RFKKEGVLGVVKDVFLPWYNAYRFLVQNAKRLETE 705

  Fly   699 SGEKLIRTSDKSYLNRYLLSQ--------LVEFESEVEKLYQAYEYNRVVACVQNFIANQVSAVY 755
            .|...:.|...:..:..:|.|        ||.|..|....|:.|   .||..:..|:.| ::.:|
plant   706 GGVPFVPTDLATIQSANILDQWIHSATQSLVRFVREEMDAYRLY---TVVPRLLKFLDN-LTNIY 766

  Fly   756 VHLIKDRL--YCGDD--HELLAIRQTLTHCYQQLCKSLWPIVPFLVE 798
            |...:.||  ..|:|  |..|:   ||.:.....||.:.|..||..|
plant   767 VRFNRKRLKGRTGEDDCHTALS---TLFNVLLTSCKVMAPFTPFFTE 810

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
IleRS-m	NP_648837.2	ileS	26..938	CDD:235588	245/892 (27%)
		nt_trans	75..>211	CDD:294020	49/160 (31%)
		nt_trans	<434..658	CDD:294020	73/251 (29%)
		Anticodon_Ia_Ile_BEm	668..842	CDD:153414	39/167 (23%)
AT4G10320	NP_192770.2	PLN02882	3..1186	CDD:215477	245/892 (27%)
		nt_trans	40..>182	CDD:294020	49/160 (31%)
		IleRS_core	<436..672	CDD:173909	76/282 (27%)
		Anticodon_Ia_Ile_ABEc	672..858	CDD:153415	35/146 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0060
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60783
OrthoDB	1	1.010	-	-		D59501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830