Protein Alignment IleRS-m and LeuRS-m

DIOPT Version :9

• Sequence 1: NP_648837.2
• Gene: IleRS-m / 39762
• FlyBaseID: FBgn0036569
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_647932.1
• Gene: LeuRS-m / 38581
• FlyBaseID: FBgn0027085
• Length: 869
• Species: Drosophila melanogaster
• Alignment Length: 978
• Identity: 193/978 - (19%)
• Similarity: 313/978 - (32%)
• Gaps: 385/978 - (39%)

  Fly    84 PYANGQLHMGHA-VNKILKDITLRQRVAHGQRVNYIPGWDCHGLPIELKATSTAPGQSAQEIRQK 147
            ||.:|.|||||. |..|...:...||:. |:.|....|||..|||.|         .:|.:...:
  Fly    71 PYPSGNLHMGHVRVYTIADSVARFQRMC-GKNVFQPMGWDSFGLPAE---------NAANQRGVE 125

  Fly   148 SRAFAWEAIKSQKEEFSSWGILANWQKDNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWS 212
            ..::..:.|...||:....|...:|..:  ..|..|::......:|..|:..||.|::...|.|.
  Fly   126 PASWTEQNIAQMKEQLKRLGCSFDWNHE--LSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWD 188

  Fly   213 PSSRTALAEAELEYDAN------------------HISPSVYVRFAL----NPSSFDVKD----- 250
            |..:|.||:.::  |||                  .|..|.|.:..|    :|:..|.:|
  Fly   189 PVDKTVLADEQV--DANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRDIINLQ 251

  Fly   251 ------KQIYAL-----------VWTTTPWTLPSNQAICYNASLEYVIVRLSDRNQDELYLMASA 298
                  ...||.           ||||.|..|....|        ::::|
  Fly   252 RHWIGECDGYAFNLLTSASGLLRVWTTHPEHLKDPHA--------FLVLR--------------- 293

  Fly   299 LMADFEANTQLKCEIVQHLSGELLSKLSYNHPIDKEQSNLPFFDASHVQDSKGTGLVHTA-PAHG 362
                                        .||               |:...||...:..| |..|
  Fly   294 ----------------------------SNH---------------HLSKLKGADSLSAANPFAG 315

  Fly   363 PEDFLVSLTQKIPVKCFVNEEGTYTKEAPDFLRGKSVLDQGNSLVLDRIAEDVVHSSKLEHSY-P 426
                     ..:||  ..::|.|:..::..:|...|...:...| .|........:.|.|.|. |
  Fly   316 ---------TTMPV--VFSDEVTFPPKSDVYLAAPSFRGEDKDL-WDSYGLAFTSNGKDEESLSP 368

  Fly   427 IDWRTKKPVIIRASEQWFINTEKLKTPAADALEQVEIYPRANAEASKKALLTQLQKRPYWCISRQ 491
            .:|...:..:::|:.:..:...::.:...|                             |.||||
  Fly   369 ANWEMLRKEVLQAATRLNVGGYRVSSKLKD-----------------------------WLISRQ 404

  Fly   492 RAWGVPIPVLYSRESGKVVLNSALIEHLCNLLRKEGSIDFWWVKSVEELVPEHL-LRELHHEA-- 553
            |.||.|||:::.::.|.|.:                         .||.:|..| .::...||
  Fly   405 RYWGTPIPIVHCQKCGAVPV-------------------------PEEQLPVSLPPKDSPKEAFL 444

  Fly   554 --------KDLVKGTDILDIWFDSGSTW----------------SAVLGKDKIADLYLEG----- 589
                    ||..:.||.:|.:.|  |:|                :|:..|....|||:.|
  Fly   445 CDCPKCGEKDARRETDTMDTFVD--SSWYYLRYLDAQNSERIFDTALTKKFMPVDLYIGGKEHAV 507

  Fly   590 ----YDQFTGWFQSSLLMSIAARECAPYKALFVHG------FTVDEKG----------------- 627
                |.:|...|..|..:|..:.   |:..|.|.|      |.|...|
  Fly   508 LHLYYARFINHFLHSCGLSPTSE---PFSRLLVQGMVMGRSFRVKGSGRYVPETEVEIVNAKKNQ 569

  Fly   628 --------------YKMSKSLGNVISPKQITKKYGTDALR--------------WWVAS-----H 659
                          .|||||..|.:.|..:..:||||..|              |..|:     :
  Fly   570 AVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPTSHRNWSSATFPGILN 634

  Fly   660 GTQHMSITVSDKLLQQAAENLCKIRGTMRYLKGVIGEKQSGEKLIRTSDKSYLNRYLLSQLVEFE 724
            ..:.:.:|:.|  .|||.|:                  |:...::.||:             ||.
  Fly   635 WQKRLWLTLQD--FQQARED------------------QTASDVVPTSE-------------EFL 666

  Fly   725 SEVEKLYQAYEYNRVVACVQNFIANQVSAVYVHLIKDRLYCGDDHELL-AIRQTLTHCYQ----- 783
            :|..||:.|          :||.....:..|.|..:..:.......|. ::|:|..|..:
  Fly   667 AEDAKLFDA----------RNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQF 721

  Fly   784 ------QLCKSLWPIVPFLVEESWSYYDTTGGAFHEQIVQTNPEWQDTKATEVINAAFDVKRLIN 842
                  |:. .|.|:.|....|.||.:....|       :.||..|:.:.:|.:.|
  Fly   722 ERALAAQII-MLAPMAPHFASELWSKFVAIPG-------RLNPASQELQWSEDVLA--------- 769

  Fly   843 QQAGDVN-TWHLAVTIKGKERSQLDLLRELHSPLGESVSNSELCEILQVGSVTLLQ-SHNSDLDI 905
            |:..|:: .::|.::||                    |:..|.| :::|....|.: :|:..|||
  Fly   770 QRWPDIDPAYNLDLSIK--------------------VNGFENC-VIKVQRTHLDKVTHSDALDI 813

  Fly   906 ALS 908
            |.:
  Fly   814 AFN 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IleRS-m	NP_648837.2	ileS	26..938	CDD:235588	193/978 (20%)
		nt_trans	75..>211	CDD:294020	35/127 (28%)
		nt_trans	<434..658	CDD:294020	60/310 (19%)
		Anticodon_Ia_Ile_BEm	668..842	CDD:153414	35/185 (19%)
LeuRS-m	NP_647932.1	leuS	40..848	CDD:234743	193/978 (20%)
		LeuRS_core	63..624	CDD:173906	140/703 (20%)
		Anticodon_Ia_like	624..747	CDD:299868	32/166 (19%)
		Anticodon_Ia_like	<723..799	CDD:299868	22/113 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446754
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840