Protein Alignment IleRS-m and iars1

DIOPT Version :10

• Sequence 1: NP_648837.2
• Gene: IleRS-m / 39762
• FlyBaseID: FBgn0036569
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_956190.3
• Gene: iars1 / 334393
• ZFINID: ZDB-GENE-030131-6325
• Length: 1271
• Species: Danio rerio
• Alignment Length: 988
• Identity: 258/988 - (26%)
• Similarity: 414/988 - (41%)
• Gaps: 205/988 - (20%)

  Fly    47 EEQERLVLENKIAVSYAYQEQRLAEKGKPTFVLHDGPPYANGQLHMGHAVNKILKDITLRQRVAH 111
            ||::.|....|   :..:||.....|.:|.|..:||||:|.|..|.||.:...:|||..|....:
Zfish    14 EEEQILQFWQK---NDCFQECLKQSKSRPRFTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQN 75

  Fly   112 GQRVNYIPGWDCHGLPIE--------LKATSTAPGQSAQEIRQKSRAFAWEAIKSQKEEFSSWGI 168
            |..|....||||||||:|        :|..........:|..::.|:.........:......|.
Zfish    76 GFHVERRFGWDCHGLPVEYEIDKSLNIKGPEDVMKMGIEEYNKQCRSIVMRYADEWENSVRRMGR 140

  Fly   169 LANWQKDNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWSPSSRTALAEAELEYDANHI-S 232
            ..:::.|  |.|..|.|:.....:|..||:.|||||.:|.:.:|.:..|.|:..|...:...: .
Zfish   141 WIDFRND--YKTLYPWFMETVWWVFKQLYDSGLVYRGVKVMPFSTACNTPLSNFEANQNYKDVQD 203

  Fly   233 PSVYVRFALNPSSFDVKDKQIYALVWTTTPWTLPSNQAICYNASLEYVIVRLSDRNQDELYLMAS 297
            |||.|.|.|      ::|..:..:.|||||||||||.|:|.|..|.|  ||:.|.:..::|:|..
Zfish   204 PSVIVNFPL------LEDPSVSLIAWTTTPWTLPSNLALCVNPELIY--VRVKDNSSQKIYIMME 260

  Fly   298 A-LMADFEANTQLKCEIVQHLSGELLSKLSYNHPID-----KEQSNLPFFDASHVQDSKGTGLVH 356
            | |:|.|:::::.  .|::...|:.|....|....:     ||.........::|:|..|||:||
Zfish   261 ARLIALFKSDSEY--TILERFPGKTLKGKKYKPLFEYFIKCKETGAFSVVMDNYVRDDDGTGVVH 323

  Fly   357 TAPAHGPEDFLVSLTQKI------PVKCFVNEEGTYTKEAPDFLRGKSVLDQGNSLVLDRIAED- 414
            .||..|.:|:.|.:...|      |: |.|:..|.:|.|...| .|:.|.|...: ::..:.|:
Zfish   324 QAPYFGADDYRVCMEYDIIQRDSAPI-CPVDPSGIFTPEVTHF-AGQYVKDADKN-IIKWLKENG 385

  Fly   415 -VVHSSKLEHSYPIDWRTKKPVIIRASEQWFINTEKLKTPAADALEQVEIYPRANAEASKKALLT 478
             :|.:|..:||||..||:..|:|.:|...|||..|.:.....|...:....|..   ..:|....
Zfish   386 RLVSASSFKHSYPFCWRSDTPLIYKAVPSWFIRVEHMVEKLLDNNSKCYWVPEF---VKEKRFGN 447

  Fly   479 QLQKRPYWCISRQRAWGVPIPVLYSRESGKVVLNSALIEHLCNLLRKEGSIDFWWVKSVEELVPE 543
            .|:....|.:||.|.||.|||:..|.:..:||...::.|                   :|||...
Zfish   448 WLRDARDWAVSRNRYWGTPIPLWVSDDFEEVVCVGSMAE-------------------LEELTGI 493

  Fly   544 HLLRELHHEAKD------------LVKGTDILDIWFDSGSTWSAVLG---------KDKI-ADLY 586
            . :.:||.|:.|            |.:.:::.|.||:|||...|.:.         :|.. ||..
Zfish   494 K-VTDLHRESIDGLTIPSRCGKGQLRRVSEVFDCWFESGSMPYAQVHYPFENRREFEDAFPADFI 557

  Fly   587 LEGYDQFTGWFQSSLLMSIAARECAPYKALFVHGFTVDEKGYKMSKSLGNVISPKQITKKYGTDA 651
            .||.||..|||.:.|::|.|.....|:|.:.|:|..:...|.||||...|...|..|.:.||.||
Zfish   558 AEGIDQTRGWFYTLLVLSTALFGKPPFKNVIVNGLVLASDGQKMSKRKKNYPDPGLIVQSYGADA 622

  Fly   652 LRWWVASHGTQHMSITVSDKLLQQAAENL-CKIRGTMRYLKGVI----------------GEKQS 699
            ||.::           ::..:::  |||| .|..|....||.|.                .:|:.
Zfish   623 LRLYL-----------INSPVVR--AENLRFKEEGVRDVLKDVFLPWYNAYRFLVQNVQRLQKEE 674

  Fly   700 GEKLI---RTSDKS--YLNRYLLS---QLVEFESEVEKLYQAYEYNRVVACVQNFIANQVSAVYV 756
            |.:.:   |||..|  .:::::.|   .|::|..:....|:.|   .||..:..|: :.::..||
Zfish   675 GVEFLYNERTSSVSNNIMDKWIQSFTQSLIQFFRDEMGAYRLY---TVVPKLVKFV-DMLTNWYV 735

  Fly   757 HLIKDRLYCGDDHELLAIR--QTLTHCYQQLCKSLWPIVPFL----------------VEESWSY 803
            .:.:.||. |:......:|  :||......:|:.:.|..||:                |||.
Zfish   736 RMNRRRLK-GESGSEDCVRALETLFSVLFSMCRLMAPFTPFITELMYQNLRHLLDPAAVEEK--- 796

  Fly   804 YDTTGGAFH-----------------------EQIVQTNPEWQDTKA-------TEVI------N 832
             ||  |:.|                       :.:::.....:|.|.       .||:      .
Zfish   797 -DT--GSIHYLMLPQVRESLIDQRIESAVSRMQSVIELGRVIRDRKTLPIKYPLKEVVVIHQDPE 858

  Fly   833 AAFDVKRLINQQAGDVNTWHLAVTIKGKERSQLDLLREL-HSPLG--------------ESVSNS 882
            |..|::.|.|....::|...|.:: ..|:|..:.|..|. |..||              :.:.:.
Zfish   859 ALTDIQSLQNYILEELNVRQLTLS-TDKDRYGIRLRAEPDHMVLGKRLKGAFKSVTASIKELKSE 922

  Fly   883 ELCEILQVGSVTL 895
            ||.|..:.|.:.:
Zfish   923 ELEEFQKTGCIVV 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IleRS-m	NP_648837.2	IleS	26..936	CDD:439830	258/988 (26%)
iars1	NP_956190.3	None