Protein Alignment IleRS-m and LeuRS

DIOPT Version :9

• Sequence 1: NP_648837.2
• Gene: IleRS-m / 39762
• FlyBaseID: FBgn0036569
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_001285589.1
• Gene: LeuRS / 326262
• FlyBaseID: FBgn0284253
• Length: 1182
• Species: Drosophila melanogaster
• Alignment Length: 1077
• Identity: 206/1077 - (19%)
• Similarity: 381/1077 - (35%)
• Gaps: 338/1077 - (31%)

  Fly    41 LTAAKREEQERLVLENKIAVSYA--YQEQRLAEKGKPTFVLHDGPPYANGQLHMGHAVNKILKDI 103
            |...:||.|:|...| ::..|.|  ..::|.|||...||..    ||.||:||:||..:....:.
  Fly    15 LQKIEREVQQRWEAE-RVHESDAPTAPKKRQAEKFFVTFPF----PYMNGRLHLGHTFSLSKAEY 74

  Fly   104 TLRQRVAHGQRVNYIPGWDCHGLPI---------ELKATSTAP------------GQSAQEI--- 144
            ::|.....|:||.:..|:.|.|:||         ||:.....|            .::|.|:
  Fly    75 SMRYHRLKGRRVLWPFGFHCTGMPIKACADKLTRELEQFGFPPQFPETEEVVPVAAEAASEVPKD 139

  Fly   145 ---RQKSRAFA--------WEAIKS------QKEEFSS---W---------------GILANWQK 174
               .:||:|.|        |:.::|      :.::|::   |               |:..:|::
  Fly   140 KSKGKKSKAVAKTGAAKYQWQIMQSLGLKDEEIKDFANAEHWLNYFPPLAVQDLKRIGVHVDWRR 204

  Fly   175 DNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWSPSSRTALAEAELEYDANH---ISPSVY 236
            ..|.....|.|.......|.:|.|:|.:....:...:||..    .:..:::|.:.   :.|..|
  Fly   205 TFITTDANPYFDSFVRWQFNHLKERGKIMYGKRYTIYSPKD----GQPCMDHDRSSGEGVGPQEY 265

  Fly   237 VRFALN----PSSFDVKDKQIYALVWTTTPWTLPSNQAICY-NASLEYVIVRLSDRNQDELYLMA 296
            ....:.    |.:.....:.|:.:..|..|.|: ..|..|: :..::|:..:.:..|:..:....
  Fly   266 TLIKMKVLEVPKALSSIKQPIFMVAATLRPETM-YGQTNCWLHPDIKYIAWQANKNNEVWVSTRR 329

  Fly   297 SALMADFEANTQLKCEI--VQHLSGELLSKLSYNHPIDKEQ--SNLPFFDASHVQDSKGTGLVHT 357
            :|....::..|.::.||  :..::|:.|..:..:.|:.|.:  .:||...   :::.||||:|.:
  Fly   330 AARNMTYQGFTAVEGEIKVLAEVTGQDLLGVPLSAPLTKHKVVYSLPMLS---IKEDKGTGVVTS 391

  Fly   358 APAHGPEDF--LVSLTQK-------------------IPV------------------------- 376
            .|:..|:|:  ||.|.:|                   ||:
  Fly   392 VPSDSPDDYAALVDLQKKEAFRQKYGLKDEMVLPYEPIPIIEVPTLGKLSAVHAYETLKIQSQND 456

  Fly   377 --KCFVNEEGTYTKEAPD------FLRGKSVLDQGNSL---VLDRIAEDVVHSSKLEHSYPIDWR 430
              |....:|..|.|...|      ...|:.:.|....|   ::|....||.:    |....|..|
  Fly   457 KDKLAEAKEMCYLKSFYDGVMLVGAFAGRKIQDVKKDLQKRLVDANEADVYY----EPEKTIMSR 517

  Fly   431 TKKPVIIRASEQWFIN--TEKLKTPAADALEQVEIYPRANAEASKKALLTQLQKRPYWCISRQRA 493
            :....::....||::|  ..:.:..|...|..:|.: ...|..:.:|.|..|.:  |.| ||...
  Fly   518 SADECVVALCNQWYLNYGEPEWQAQATKILHGMETF-HEEARNNFEACLNWLHE--YAC-SRTYG 578

  Fly   494 WGVPIP---------------------VLYSRESG------------------------------ 507
            .|..:|                     |::..:.|
  Fly   579 LGTKLPWDDKWLIESLSDSTIYMAFYTVVHLLQGGTFRGEKPGPFGIKPSDMTGEIWDYIFFKET 643

  Fly   508 ----KVVLNSALIEHLCNLLRKEGSIDFWWVK----SVEELVPEHLLRELHHEAKDLVKGTDILD 564
                |..:..   |||. :||:|  .::|:..    |.::|:..||...|::.|.
  Fly   644 PLPKKTAIKQ---EHLA-VLRRE--FEYWYPMDLRVSGKDLIQNHLTFCLYNHAA---------- 692

  Fly   565 IWFDSGSTWSAVLGKDKIADLYLEGYDQFTGWFQSSLLMSIAARECAPYKALFVHGFTVDEKGYK 629
            ||.:..:.|.        ..:.:.|:          ||::.|                      |
  Fly   693 IWPNDENKWP--------KGMRVNGH----------LLLNSA----------------------K 717

  Fly   630 MSKSLGNVISPKQITKKYGTDALRWWVASHGTQHMSITVSDKLLQQAAENLCKIRGTMRYLKGVI 694
            ||||.||.::..:...|:..|.:|..:|..|.   |:..::.:...|...:.::...:.::|.::
  Fly   718 MSKSDGNFLTLTEAVDKFSADGMRLCLADAGD---SVEDANFVESTADAGILRLYTFIEWVKEML 779

  Fly   695 GEKQSGEKLIRTSDKSYLNRYLLSQLVEFESEVEKLYQAYEYNRVVACVQNFIANQVSAVY-VHL 758
            ..:.|   |.:.:||::.::..||:|.....:.::.|:...:...:.          |..| :.|
  Fly   780 ENRSS---LRKGTDKTFNDQVFLSELNLKTQQTDENYRKMLFKEALR----------SGFYELQL 831

  Fly   759 IKD--RLYCGDD--HELLAI----RQTLTHCYQQLCKSLWPIVPFLVEESWSYYDTTGGAFHEQI 815
            .:|  |..||.:  ||.|.:    ||.|.         :.||.|.:.|..|..........|.:
  Fly   832 ARDKYRELCGANGMHEDLVLEFIRRQALL---------VSPICPHMAEHVWGLLGNKESIVHAR- 886

  Fly   816 VQTNPEWQDTKATE---------VINAA----FDVKRL------------INQQAGDVN---TWH 852
                  |.:..|..         ::.||    .::|.|            :|.||...|   .|
  Fly   887 ------WPEVGAINEVDILCSEYLMEAAHSFRLNLKNLLQIKGKAGKDKSVNVQAAKPNRGLVW- 944

  Fly   853 LAVTIKGKERSQLDLLRELHSPLGESVSNSELCEILQ 889
            :|.|....:...||.::||.:.......|..:...||
  Fly   945 VAKTYPPWQCCVLDTMKELFNKSQALPDNKVIAATLQ 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IleRS-m	NP_648837.2	ileS	26..938	CDD:235588	206/1077 (19%)
		nt_trans	75..>211	CDD:294020	41/194 (21%)
		nt_trans	<434..658	CDD:294020	49/284 (17%)
		Anticodon_Ia_Ile_BEm	668..842	CDD:153414	35/207 (17%)
LeuRS	NP_001285589.1	PLN02959	1..1068	CDD:215518	206/1077 (19%)
		nt_trans	47..>204	CDD:294020	35/160 (22%)
		LeuRS_core	<525..758	CDD:173906	52/295 (18%)
		Anticodon_Ia_Leu_AEc	756..876	CDD:153413	28/141 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446757
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930