Protein Alignment IleRS-m and iars1

DIOPT Version :9

• Sequence 1: NP_648837.2
• Gene: IleRS-m / 39762
• FlyBaseID: FBgn0036569
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_001090690.1
• Gene: iars1 / 100036668
• XenbaseID: XB-GENE-1001585
• Length: 1259
• Species: Xenopus tropicalis
• Alignment Length: 1036
• Identity: 269/1036 - (25%)
• Similarity: 435/1036 - (41%)
• Gaps: 227/1036 - (21%)

  Fly    23 AKKYTDTINLPKTKFPNRLTAAKREEQERLVLENKIAVSYAYQEQRLAEKGKPTFVLHDGPPYAN 87
            |::..::||.|            .||::.|.|...:.   .:||.....|.:|.:..:||||:|.
 Frog     2 AQQVPESINFP------------TEEEKILELWKSLD---CFQECLKQSKNRPRYTFYDGPPFAT 51

  Fly    88 GQLHMGHAVNKILKDITLRQRVAHGQRVNYIPGWDCHGLPIELKATSTAPGQSAQEIRQKSRAFA 152
            |..|.||.:...:|||..|.....|..|....||||||||:|.:...|...:..:::.:...|..
 Frog    52 GLPHYGHILAGTIKDIVTRFAHQSGFHVERRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEY 116

  Fly   153 WEAIKSQKEEFS-SWGI----LANW-QKDNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYW 211
            .:..:.....:| .|.|    |..| ...|.|.|..|.|:.....:|..||:||||||.:|.:.:
 Frog   117 NKQCRGIVMRYSQEWEISVTRLGRWIDFKNDYKTLYPWFMETVWWVFKQLYDKGLVYRGVKVMPF 181

  Fly   212 SPSSRTALAEAELEYDANHI-SPSVYVRFALNPSSFDVKDKQIYALVWTTTPWTLPSNQAICYNA 275
            |.:..|.|:..|...:...: .|||.|.|.|      :.|..:..:.|||||||||||.|:|.|.
 Frog   182 STACNTPLSNFESHQNYKDVQDPSVIVTFPL------LDDSGVSLVAWTTTPWTLPSNLALCVNP 240

  Fly   276 SLEYVIVRLSDRNQDELY-LMASALMADFEANTQLKCEIVQHLSGELLSKLSYNHPIDKEQSNLP 339
            .|.|  |:|.|::...:| ||.:.|.|.::|..:.  :|::...|..|....|. |:      .|
 Frog   241 ELIY--VKLKDKSNGNVYILMEARLSALYKAENEY--DILERFPGNNLKGKKYK-PL------FP 294

  Fly   340 FFDA------------SHVQDSKGTGLVHTAPAHGPEDFLV----SLTQK--IPVKCFVNEEGTY 386
            :|:.            ::|:..:|||:||.||..|.:|:.|    ::.||  :|| |.|:..|.:
 Frog   295 YFEKASERGAFTVVTDNYVKSEEGTGVVHQAPYFGADDYRVCMDFNIIQKDSVPV-CPVDASGCF 358

  Fly   387 TKEAPDFLRGKSVLDQGNSLVLDRIAED---VVHSSKLEHSYPIDWRTKKPVIIRASEQWFINTE 448
            |||..|| .|:.|.|...:::  ::.::   :||||..:|:||..||:..|:|.:|...||:..|
 Frog   359 TKEVTDF-AGQYVKDADKNII--KLLKEHGRLVHSSSYKHNYPFCWRSDTPLIYKAVPSWFVRVE 420

  Fly   449 KLKTPAADALEQVEIYPRANAEASKKALLTQLQKRPYWCISRQRAWGVPIPVLYSRESGKVVLNS 513
            .:.........|....|....|   |.....|:....|.|||.|.||.|||:..|.:..:||...
 Frog   421 HMVDKLLQNNSQCYWVPEFVRE---KRFGNWLKDARDWAISRNRYWGTPIPLWVSEDFEEVVCVG 482

  Fly   514 ALIEHLCNLLRKEGSIDFWWVKSVEELVPEHLLRELHHEAKD------------LVKGTDILDIW 566
            :|.|                   :|||.... :.:||.|:.|            |.:.|::.|.|
 Frog   483 SLAE-------------------LEELTGTK-VTDLHRESVDHLTIPSRRGKGSLRRVTEVFDCW 527

  Fly   567 FDSGSTWSAVLG---------KDKI-ADLYLEGYDQFTGWFQSSLLMSIAARECAPYKALFVHGF 621
            |:|||...|.:.         :|.. ||...||.||..|||.:.|::|.|.....|:|.:.|:|.
 Frog   528 FESGSMPYAQVHYPFENRREFEDCFPADFIAEGIDQTRGWFYTLLVLSTALFGQPPFKNVIVNGL 592

  Fly   622 TVDEKGYKMSKSLGNVISPKQITKKYGTDALRWWVASHGTQHMSITVSDKLLQQAAENL-CKIRG 685
            .:...|.|||||..|...|.|:...||:||||.::           ::..:::  |||| .|..|
 Frog   593 VLASDGQKMSKSKKNYPDPMQVINSYGSDALRLYL-----------INSPVVR--AENLRFKEDG 644

  Fly   686 TMRYLKGV-----------------IGEKQSGEKLIRTSDKSYLNRYLLSQLVEFESEVEKLYQ- 732
            ....||.|                 :.::::...|...|.|...|..:...::.|...:.:.::
 Frog   645 VRDVLKDVFLPWYNAYRFLMQNIYRLHKEENIHFLFNESTKQQSNNIMDQWIISFTQSLVQFFKA 709

  Fly   733 ---AYEYNRVVACVQNFIANQVSAVYVHLIKDRL--YCGDDHELLAIRQTLTHCYQQLCKSLWPI 792
               ||....||..:..|: :.::..||.:.:.||  ..|.:...:|: :||......:|:.:.|.
 Frog   710 EMSAYRLYTVVPRLVKFV-DMLTNWYVRMNRRRLKGESGTEDCQMAL-ETLFSVLFSMCRLMAPF 772

  Fly   793 VPFLVEESW----------SYYDTTGGAFH-----------------------EQIVQTNPEWQD 824
            .||:.|..:          |..|....:.|                       :.:::.....:|
 Frog   773 TPFITEMMYQKLRLLIDPSSMQDKDTKSIHYLMLPTAREDLIDKKIESAVSRMQSVIELGRVIRD 837

  Fly   825 TKA-------TEVI------NAAFDVKRLINQQAGDVNTWHLAVT-------------------- 856
            .|.       .|||      .|..|:|.|......::|...:.|:
 Frog   838 RKTLPVKYPLKEVIVIHQDSEALADIKSLEKYIKEELNVKQVTVSTNKDKYGIRLRAEPDHMVLG 902

  Fly   857 --IKGKERSQLDLLRELHSPLGESVSNSELCEILQVGSVTL--LQSHNSDLDIALSKLQIS 913
              :||..::.:..::||.|        ::|.|..:.||:.:  .:.|..|:.:..:..|:|
 Frog   903 KRLKGAFKTVMAAIKELKS--------NQLEEFQKTGSIVVDGHELHEEDIRLLYTFDQVS 955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IleRS-m	NP_648837.2	ileS	26..938	CDD:235588	268/1033 (26%)
		nt_trans	75..>211	CDD:294020	47/141 (33%)
		nt_trans	<434..658	CDD:294020	74/245 (30%)
		Anticodon_Ia_Ile_BEm	668..842	CDD:153414	44/243 (18%)
iars1	NP_001090690.1	PLN02882	6..1077	CDD:215477	268/1032 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101703at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010