DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynbetaL and ATPsynbeta

DIOPT Version :9

Sequence 1:	NP_648836.2	Gene:	ATPsynbetaL / 39761	FlyBaseID:	FBgn0036568	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001259081.1	Gene:	ATPsynbeta / 43829	FlyBaseID:	FBgn0010217	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	465	Identity:	354/465 - (76%)
Similarity:	405/465 - (87%)	Gaps:	1/465 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 GVIHAVIGPVIDVYFEEEVPEVLNALQVQDAPIANLVLEVFHHLGNNIVRCVAMDSTEGLRRGQP 168
            |.|.||||.|:||.|::.:|.:||||:| |.....|||||..|||.|.||.:|||.||||.|||.
  Fly    44 GKIVAVIGAVVDVQFDDNLPPILNALEV-DNRSPRLVLEVAQHLGENTVRTIAMDGTEGLVRGQK 107

  Fly   169 VLDTGYPIRVAVGKAVLGRILNVVGDPIDDRGEVKSDFYSFIHNEAPELTDLSVKPEILVTGIKV 233
            |||||||||:.||...||||:||:|:|||:||.:.:|..:.||.||||...:||:.|||||||||
  Fly   108 VLDTGYPIRIPVGAETLGRIINVIGEPIDERGPIDTDKTAAIHAEAPEFVQMSVEQEILVTGIKV 172

  Fly   234 IDLLAPYVKGGKIGLFGGAGVGKTVLIMELINNIAKSHGGYSVFVGAGERTREGNDLYHEMIESK 298
            :||||||.|||||||||||||||||||||||||:||:|||||||.|.|||||||||||:||||..
  Fly   173 VDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYNEMIEGG 237

  Fly   299 VISLEDDSSKVVLVFGQMNEPPGARSRVVLTGLTIAEYFRDVDGQDVLLFIDNIFRFTQAGSEVS 363
            ||||:|.:|||.||:||||||||||:||.|||||:||||||.:||||||||||||||||||||||
  Fly   238 VISLKDKTSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVS 302

  Fly   364 ALLGRIPSAVGYQPTLGTDMGTMQERITSTRNGSITSVQAVYVPADDLSDPAPAATFSHLDATTV 428
            ||||||||||||||||.||||:||||||:|:.||||||||:|||||||:|||||.||:|||||||
  Fly   303 ALLGRIPSAVGYQPTLATDMGSMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTV 367

  Fly   429 LSRPIAELGIYPAVDPLDSSSRILDPDVVGEEHYNVARAVQKTLQAYKSLQDIIAILGMDELSEE 493
            |||.|||||||||||||||:|||:||:::|:|||||||.|||.||.|||||||||||||||||||
  Fly   368 LSRAIAELGIYPAVDPLDSTSRIMDPNIIGQEHYNVARGVQKILQDYKSLQDIIAILGMDELSEE 432

  Fly   494 DKLTVARARKMQRFLSQPFQVAEIFTGHPGKLVPVEKCVEGFKRLLNGEYDDIPEIAFYMVGDAE 558
            ||||||||||:||||||||||||:||||.|||||:|:.::||..:|.|:||.:||:||||||..|
  Fly   433 DKLTVARARKIQRFLSQPFQVAEVFTGHAGKLVPLEQTIKGFSAILAGDYDHLPEVAFYMVGPIE 497

  Fly   559 EVLAKATQLA 568
            ||:.||.:||
  Fly   498 EVVEKADRLA 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynbetaL	NP_648836.2	PRK09280	103..568	CDD:236447	352/463 (76%)
		ATP-synt_ab_N	106..173	CDD:280947	40/66 (61%)
		F1-ATPase_beta	175..454	CDD:238553	223/278 (80%)
		ATP-synt_ab_C	462..571	CDD:278722	82/107 (77%)
ATPsynbeta	NP_001259081.1	PRK09280	44..507	CDD:236447	352/463 (76%)
		ATP-synt_ab_N	46..112	CDD:280947	40/66 (61%)
		F1-ATPase_beta	114..393	CDD:238553	223/278 (80%)
		ATP-synt_ab_C	401..508	CDD:278722	82/107 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464267
Domainoid	1	1.000	175	1.000	Domainoid score	I1096
eggNOG	1	0.900	-	-		E1_COG0055
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	586	1.000	Inparanoid score	I11
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62497
OrthoDB	1	1.010	-	-		D27491at7147
OrthoFinder	1	1.000	-	-		FOG0001822
OrthoInspector	1	1.000	-	-		otm51317
orthoMCL	1	0.900	-	-		OOG6_100608
Panther	1	1.100	-	-	P	PTHR15184
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1349
	12	11.810