DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynbetaL and blw

DIOPT Version :9

Sequence 1:	NP_648836.2	Gene:	ATPsynbetaL / 39761	FlyBaseID:	FBgn0036568	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_726243.1	Gene:	blw / 37617	FlyBaseID:	FBgn0011211	Length:	552	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	123/522 - (23%)
Similarity:	210/522 - (40%)	Gaps:	91/522 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 QEVCKT---DAELVKKK---------DEAEDECEEK------KSDGGGKKLESKGRKGVIHAVIG 111
            |..||.   .|.|..:|         .|..:..||:      |:|     ||..||   :.::..
  Fly    22 QVACKAAYPAASLAARKLHVASTQRSAEISNILEERILGVAPKAD-----LEETGR---VLSIGD 78

  Fly   112 PVIDVYFEEEVPEVLNALQVQD-----APIANLVLEVFHHLGNNIVRCVAMDSTEGLRRGQPVLD 171
            .:..||       .||.:|..:     :.:..:.|    :|..:.|..|...:.:.:::|..|..
  Fly    79 GIARVY-------GLNNIQADEMVEFSSGLKGMAL----NLEPDNVGVVVFGNDKLIKQGDIVKR 132

  Fly   172 TGYPIRVAVGKAVLGRILNVVGDPIDDRGEVKSDFYSFIHNEAPELTD-LSVKPEILVTGIKVID 235
            ||..:.|.||..:|||:::.:|:.||.:|.:.:.....:..:||.:.. :||: |.:.||||.:|
  Fly   133 TGAIVDVPVGDELLGRVVDALGNAIDGKGAINTKDRFRVGIKAPGIIPRVSVR-EPMQTGIKAVD 196

  Fly   236 LLAPYVKGGKIGLFGGAGVGKTVLIMELINNIAK-------SHGGYSVFVGAGERTREGNDLYHE 293
            .|.|..:|.:..:.|....|||.|.::.|.|..:       |...|.::|..|::......:...
  Fly   197 SLVPIGRGQRELIIGDRQTGKTALAIDTIINQKRFNEAQDESKKLYCIYVAIGQKRSTVAQIVKR 261

  Fly   294 MIESKVISLEDDSSKVVLVFGQMNEPPGARSRVVLTGLTIAEYFRDVDGQDVLLFIDNIFRFTQA 358
            :.:|..:...      |:|....::....:.....:|..:.||||| .|:..|:..|::.:...|
  Fly   262 LTDSGAMGYS------VIVSATASDAAPLQYLAPYSGCAMGEYFRD-KGKHALIIYDDLSKQAVA 319

  Fly   359 GSEVSALLGRIPSAVGYQPTLGTDMGTMQERIT----STRNGSITSVQAVYVPADDLSDPAPAAT 419
            ..::|.||.|.|....|...:......:.||..    :...||:|::..:...|.|:|...|...
  Fly   320 YRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSPAMGGGSLTALPVIETQAGDVSAYIPTNV 384

  Fly   420 FSHLDATTVLSRPIAELGIYPAVDPLDSSSRILDPDVVG-----EEHYNVARAVQKTLQAYKSLQ 479
            .|..|....|...:...||.||::...|.||      ||     :....||.:::..|..|:.:.
  Fly   385 ISITDGQIFLETELFYKGIRPAINVGLSVSR------VGSAAQTKAMKQVAGSMKLELAQYREVA 443

  Fly   480 DIIAILGMDELSEEDKLTVARARKMQRFLSQ----PF----QVAEIFTG--------HPGKLVPV 528
             ..|..|.| |....:..:.|..::...|.|    |.    |||.|:.|        .|.|:...
  Fly   444 -AFAQFGSD-LDAATQQLLNRGVRLTELLKQGQYVPMAIEDQVAVIYCGVRGHLDKMDPAKITKF 506

  Fly   529 EK 530
            ||
  Fly   507 EK 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynbetaL	NP_648836.2	PRK09280	103..568	CDD:236447	108/466 (23%)
		ATP-synt_ab_N	106..173	CDD:280947	11/71 (15%)
		F1-ATPase_beta	175..454	CDD:238553	72/290 (25%)
		ATP-synt_ab_C	462..571	CDD:278722	21/85 (25%)
blw	NP_726243.1	PRK09281	46..552	CDD:236448	117/498 (23%)
		ATP-synt_ab_N	68..134	CDD:280947	14/79 (18%)
		F1_ATPase_alpha	136..417	CDD:238552	72/294 (24%)
		ATP-synt_ab_C	426..520	CDD:278722	21/85 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454771
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840