DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13074 and CG13930

DIOPT Version :9

Sequence 1:	NP_648835.1	Gene:	CG13074 / 39760	FlyBaseID:	FBgn0036567	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_647645.1	Gene:	CG13930 / 38210	FlyBaseID:	FBgn0035256	Length:	685	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	66/316 - (20%)
Similarity:	113/316 - (35%)	Gaps:	103/316 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EKQHALVDN------CTGTDPPPPSQDAATGTQEKLHVATQTEQRVVSSKDVEYDERALAKWLRQ 79
            |.:..:.||      .:|||.          |:..:...|||...::.|:.|..:....|    |
  Fly   130 EGRQVMEDNRKYDELLSGTDK----------TRRTVDADTQTMTALMKSRLVNTERLTTA----Q 180

  Fly    80 ICPMVER-ELMNP-TPLMEDLTMSQCRLEEKLQVYTYQKLIMGGAENSQG--------LAIWLCV 134
            :...|.. |:.:. |.|.:..|..|.:..:|:::.||.   :||.:...|        ||:.|.:
  Fly   181 MGSYVSNFEMYDTYTDLEKSTTSVQVQGAKKMEITTYH---VGGVDQFVGINCLPGFRLALMLTM 242

  Fly   135 HTNNAPVLVATTV-----------APHDDWCEHVDQQLKLFVPQRMSVGNLVIYTEAKTLPLKSC 188
            .      ::|:.|           ||.|...|.|..:.:|.:..|:|..:    ::.|.....|.
  Fly   243 R------ILASNVFEPQQRRYRNMAPPDPLAEDVKFKYRLGLLWRLSPPS----SDPKVHQAVSD 297

  Fly   189 LRSLCTNPFNKTMFAGSTMDGELFIWLYEQARGSDSSVDIKQLYSVSSTQGAAVALDWPREHLLL 253
            : |.|  |.|          |::....|    |..|...:.:|               ||
  Fly   298 M-SFC--PSN----------GDIMAVAY----GVYSHGKVSKL---------------PR----- 325

  Fly   254 ACFANGSVRQWDLSRQMALD--WEYTLP-ATVSSEPTAMVTLGLDDFVVGTNDGGV 306
                :|.|..|::...:..:  :.|.:| .||...||....|     .:|.::|||
  Fly   326 ----SGWVYVWNIKNPVNPERRYHYQVPVVTVEFSPTQPQLL-----AIGLHNGGV 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13074	NP_648835.1	WD40 repeat	189..234	CDD:293791	9/44 (20%)
CG13074	NP_648835.1	WD40 repeat	242..275	CDD:293791	5/34 (15%)
CG13930	NP_647645.1	WD40	<279..648	CDD:225201	29/144 (20%)
		WD40 repeat	295..344	CDD:293791	15/89 (17%)
		WD40 repeat	350..397	CDD:293791	9/28 (32%)
		WD40 repeat	400..473	CDD:293791
		WD40 repeat	478..513	CDD:293791
		WD40	<518..>593	CDD:295369
		WD40 repeat	524..560	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100