DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13074 and dync1i1

DIOPT Version :9

Sequence 1:	NP_648835.1	Gene:	CG13074 / 39760	FlyBaseID:	FBgn0036567	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001106382.1	Gene:	dync1i1 / 100127187	XenbaseID:	XB-GENE-490874	Length:	627	Species:	Xenopus tropicalis

Alignment Length:	348	Identity:	69/348 - (19%)
Similarity:	128/348 - (36%)	Gaps:	89/348 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 TQPLEKQHALVDNCTGTDPPPPSQDAATGT----------QEKLHVATQTEQRVVSSKDVEYDER 71
            |:..|:...:||..|..|....:|:....:          :||..|....|..:...:.:...||
Frog   162 TEEEEEDEEMVDLKTEHDSEFENQEEKQDSREVPPRELTEEEKQQVTHSEEFLIFFDRTIRVIER 226

  Fly    72 ALAKWLRQICPMVERELMNPTPLME---DLTMSQCRLEE---KLQVYT-------YQKLIMGGAE 123
            |||:..........|:|.:....::   :|:.::...:|   |.:|.|       |.:|::....
Frog   227 ALAEDSNIFFDYSGRDLEDKEGDIQAGANLSFNRQFYDEHWSKHRVVTCLDWSLQYPELMVASYN 291

  Fly   124 NSQGLAIWLCVHTNNAPVLVATTVAPHDDWCEHVDQQLKLFVPQRMS-VGNLVIYTEAKTLP--- 184
            |::.                    |||:              |..:: |.|:..   .||.|
Frog   292 NNED--------------------APHE--------------PDGVALVWNMKF---RKTTPEYI 319

  Fly   185 --LKSCLRSLCTNPFNKTMFAGSTMDGELFIWLYEQARGS-------DSSVDIKQLYSVS--STQ 238
              .:|.:.|:|...|:..:..|.|..|::.:|.....|.:       .::.....:|.|:  .||
Frog   320 FHCQSSVMSVCFARFHPNLVIGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPIYCVNVVGTQ 384

  Fly   239 GAAVALDWPREHLLLACFANGSVRQWDL----SRQMALDWEYTLPATVSSEPTAMVTLGLDDFVV 299
            .|         |.|:....:|.:..|.|    :.|.:::..|.....|:....|..|..:::|||
Frog   385 NA---------HNLITVSTDGKLCSWSLDMLSAPQESMELVYNKSKPVAVTGMAFPTGDVNNFVV 440

  Fly   300 GTNDGGVYRCWNTGRQTAAIKQI 322
            |:.:|.||.....|.: |.|.::
Frog   441 GSEEGTVYTACRHGSK-AGISEV 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13074	NP_648835.1	WD40 repeat	189..234	CDD:293791	9/51 (18%)
CG13074	NP_648835.1	WD40 repeat	242..275	CDD:293791	6/36 (17%)
dync1i1	NP_001106382.1	Dynein_IC2	129..156	CDD:288403
		WD40	180..598	CDD:225201	63/330 (19%)
		BALF1	<221..>276	CDD:115513	12/54 (22%)
		WD40	266..589	CDD:295369	49/244 (20%)
		WD40 repeat	274..319	CDD:293791	13/81 (16%)
		WD40 repeat	329..368	CDD:293791	7/38 (18%)
		WD40 repeat	376..419	CDD:293791	12/51 (24%)
		WD40 repeat	425..464	CDD:293791	12/39 (31%)
		WD40 repeat	480..512	CDD:293791
		WD40 repeat	518..556	CDD:293791
		WD40 repeat	564..590	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1453532at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010