Protein Alignment CG5235 and Moxd1

DIOPT Version :9

• Sequence 1: NP_001261921.1
• Gene: CG5235 / 39758
• FlyBaseID: FBgn0036565
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_067484.2
• Gene: Moxd1 / 59012
• MGIID: 1921582
• Length: 613
• Species: Mus musculus
• Alignment Length: 609
• Identity: 175/609 - (28%)
• Similarity: 297/609 - (48%)
• Gaps: 90/609 - (14%)

  Fly    42 KNWVRNEMMDSLGLYWLKWWINANENSIYFEVTVHTRGFAGLGFSKDGRLARADMVLMWVDDATG 106
            :::....::|..|.|||.|  ......:.|.:.|.|.|:.|.|||..|.:|.||:|:..|  |.|
Mouse    23 RSYPHRVVLDPEGKYWLHW--GRQGERLAFRLEVRTNGYVGFGFSPTGSMAAADIVVGGV--AHG 83

  Fly   107 HPNVLDCHGALHPSSGPPLQDDT-QNYDVLDGKQNGTHTILKFKRKIETCDPFDIPLSADTFKVL 170
            .|.:.|    ...::...|:.|. |:|.:....:|.|||:::|.|::.|||..|..|:..|.:|:
Mouse    84 RPYLQD----YFTNADRELEKDAQQDYHLDYAMENSTHTVIEFSRELHTCDVNDKSLTDSTVRVI 144

  Fly   171 WSIGENDPIHGNLDWQGQSRGVKALQLFSPMFTKNSHSIEGIQKW-DITVNNVTIDRSMDTLYWC 234
            |:...:||......:...:||.::|:|.:|   :.::.:..:..: |:...||.|. :..|.|||
Mouse   145 WAYHHDDPGESGPKYHDLNRGTRSLRLLNP---EKANVVSTVLPYFDLVNQNVPIP-NKGTTYWC 205

  Fly   235 KIVRLPELTGKQHIIGYEPLLSGKYERNVVHHMTLFECQSKIYSGSDPSSWDLWVRSAGTVC-NS 298
            ::.::|....|.|:|..||::...:| |:|||:.:::|.|.....         |...|..| :.
Mouse   206 QMFKIPTFQEKHHVIKVEPIIERGHE-NLVHHILVYQCSSNFNDS---------VLDFGHECYHP 260

  Fly   299 NLLTPRDWDSCSTPVAVWSLGSDGQFLPPHAGIPMGGASGVSYYMLEIHYDNPDGKES-VDHSGF 362
            |:  |..:.:|.|.:..|.:|.:|...|||.|:.:|......|.:||:|||||..::. :|.||.
Mouse   261 NM--PDAFLTCETVILAWGIGGEGFTYPPHVGLSLGMPLDPRYVLLEVHYDNPARRKGLIDSSGL 323

  Fly   363 RIHYTPNLRTYDSGILISGVSISETQLIPPGQKKYRSVGICGPSCSSVMFPKD---GIKIISGTL 424
            |:.:|.::|.||:|::.:|:.:|....||||..::.|.|.|...|.......:   ||.:.:..|
Mouse   324 RVFHTTDIRRYDAGVIEAGLWVSLFHTIPPGMPEFHSEGHCTLECLEEALGAEKPSGIHVFAVLL 388

  Fly   425 HSHQAGRTISLRHVRSGKELNPIIVDENYDYRHQKVHQLANETVVLPGDYLITDCSYETKYRKRP 489
            |:|.||:.|.|||.|.|:|:..:..|::||:..|:...|..|..:||||.|||:|.|.||.|...
Mouse   389 HAHLAGKGIRLRHFRKGEEMKLLAYDDDYDFNFQEFQYLREEQTILPGDNLITECRYNTKDRAVM 453

  Fly   490 TFGGYSTKEEMCLTFITYYPKIEMSGCYSMTPVREFFEMFRVYQFYSLNMTDVENMFLYNSDYTD 554
            |:||.||:.||||:::.|||::.::.|.|:..:.|..:...|.:.|
Mouse   454 TWGGLSTRNEMCLSYLLYYPRVNLTRCSSIPDIMEQLQFIGVKEIY------------------- 499

  Fly   555 YSKQAKNATNKPNSGKTSKEDVIYQESLLNKLVISDPAEFHDRTFLSHLNQLPWHDPLFTKRVEQ 619
                 :..|..|                   .:|..|.::.:.:|:..:|:..|     ||:...
Mouse   500 -----RPVTTWP-------------------FIIKSPKQYRNLSFMDAMNKFKW-----TKKEGL 535

  Fly   620 AFITGTHMTFCRVSKDSLSIPSEI 643
            :|           :|..||:|..:
Mouse   536 SF-----------NKLVLSLPVNV 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5235	NP_001261921.1	DOMON	54..174	CDD:281361	41/120 (34%)
		Cu2_monooxygen	214..354	CDD:279429	44/141 (31%)
		Cu2_monoox_C	374..529	CDD:281675	59/157 (38%)
Moxd1	NP_067484.2	DOMON_DOH	31..165	CDD:187689	44/141 (31%)
		Cu2_monooxygen	186..314	CDD:279429	44/140 (31%)
		Cu2_monoox_C	335..487	CDD:281675	58/151 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846803
Domainoid	1	1.000	126	1.000	Domainoid score	I5407
eggNOG	1	0.900	-	-		E1_KOG3568
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	291	1.000	Inparanoid score	I2777
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59784
OrthoDB	1	1.010	-	-		D1472750at2759
OrthoFinder	1	1.000	-	-		FOG0002519
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101678
Panther	1	1.100	-	-	O	PTHR10157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4667
SonicParanoid	1	1.000	-	-		X2216
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.800