Protein Alignment CG5235 and Tbh

DIOPT Version :9

• Sequence 1: NP_001261921.1
• Gene: CG5235 / 39758
• FlyBaseID: FBgn0036565
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001284996.1
• Gene: Tbh / 31718
• FlyBaseID: FBgn0010329
• Length: 670
• Species: Drosophila melanogaster
• Alignment Length: 676
• Identity: 188/676 - (27%)
• Similarity: 290/676 - (42%)
• Gaps: 149/676 - (22%)

  Fly     6 VLWIVLTVQLSFGLAYFENNQRTQDYDVDKNGSVHHKNWVRNEMMDSLGLYWLKWWI-------- 62
            :|.:::...|:..|:.|.|  |..|..:       |:.::.::   .:.|.|:..|.
  Fly    71 MLLLLMATLLTRPLSAFSN--RLSDTKL-------HEIYLDDK---EIKLSWMVDWYKQEVLFHL 123

  Fly    63 -NA-NENSIYFEVTVHTRGFAGLGFSKDGRLARADMVLMWVDDATGHPN-VLDCHGALHPSSGPP 124
             || ||...:|.          |||||.|.||.||  :.:.::..|..| |.|.:.:  |.....
  Fly   124 QNAFNEQHRWFY----------LGFSKRGGLADAD--ICFFENQNGFFNAVTDTYTS--PDGQWV 174

  Fly   125 LQDDTQNYDVLDGKQNGTHTILKFKRKIETCDPFDIPLSADTFKVLWSIGEND------------ 177
            .:|..|:.:|....:    ..|.|:||.:||||.|:.|...|..|:|:.||.:
  Fly   175 RRDYQQDCEVFKMDE----FTLAFRRKFDTCDPLDLRLHEGTMYVVWARGETELALEDHQFALPN 235

  Fly   178 ---PIHGNLDWQGQSRGVKALQLFS------PMFTKNSHSIEGIQKWDITVNNVTIDRSMDTLYW 233
               |         ...|||.|||..      |. |:..|       .:||:....|. |.:|.||
  Fly   236 VTAP---------HEAGVKMLQLLRADKILIPE-TELDH-------MEITLQEAPIP-SQETTYW 282

  Fly   234 CKIVRLP-ELTGKQHIIGYEPLLSGKYERNVVHHMTLFECQS------KIYSGSDPSSWDLWVRS 291
            |.:.||. .|..:.||:.:|||:.   ...:||||.:|.|::      .:|:|.
  Fly   283 CHVQRLEGNLRRRHHIVQFEPLIR---TPGIVHHMEVFHCEAGEHEEIPLYNGD----------- 333

  Fly   292 AGTVCNSNLLTPRDWDSCSTPVAVWSLGSDGQFLPPHAGIPMGGASGVSYYMLEIHYDNPDGKES 356
                |..  |.||. ..||..:.:|::|:.....||.||:|:||.....|..||:|::||: |:|
  Fly   334 ----CEQ--LPPRA-KICSKVMVLWAMGAGTFTYPPEAGLPIGGPGFNPYVRLEVHFNNPE-KQS 390

  Fly   357 --VDHSGFRIHYTPNLRTYDSGILISGVSISETQLIPPGQKKYRSVGICGPSCSSVMFPKDGIKI 419
              ||:|||||..:..||.||:.::..|:..::...|||||..:...|.|...|:....|..||.|
  Fly   391 GLVDNSGFRIKMSKTLRQYDAAVMELGLEYTDKMAIPPGQTAFPLSGYCVADCTRAALPATGIII 455

  Fly   420 ISGTLHSHQAGRTISLRHVRSGKELNPIIVDENYDYRHQKVHQLANETVVLPGDYLITDCSYETK 484
            ....||:|..|..:..||.|..:||..:..|:.|....|::..|..:..|||||.|:|.|.|.||
  Fly   456 FGSQLHTHLRGVRVLTRHFRGEQELREVNRDDYYSNHFQEMRTLHYKPRVLPGDALVTTCYYNTK 520

  Fly   485 YRKRPTFGGYSTKEEMCLTFITYYPKIEMSGCYSMTPVREFFEMFRVYQFYSLNMTDVENMFLY- 548
            ..|....||:|..:|||:.:|.|||..::..|.|                 |::...:||.|:|
  Fly   521 DDKTAALGGFSISDEMCVNYIHYYPATKLEVCKS-----------------SVSEETLENYFIYM 568

  Fly   549 ---NSDYTDYSKQAKNATNKPNSGKTSKEDVIY----QESLLNKLVISDPAEFHDRTFLS----- 601
               ...:..:...|:::..:.......:.|.:|    ||.|..:...||...|..|:...
  Fly   569 KRTEHQHGVHLNGARSSNYRSIEWTQPRIDQLYTMYMQEPLSMQCNRSDGTRFEGRSSWEGVAAT 633

  Fly   602 --------HLNQLPWHDPLFTKRVEQ 619
                    |....|.::||:.|.:|:
  Fly   634 PVQIRIPIHRKLCPNYNPLWLKPLEK 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5235	NP_001261921.1	DOMON	54..174	CDD:281361	39/130 (30%)
		Cu2_monooxygen	214..354	CDD:279429	45/146 (31%)
		Cu2_monoox_C	374..529	CDD:281675	51/154 (33%)
Tbh	NP_001284996.1	DOMON	102..220	CDD:281361	39/138 (28%)
		Cu2_monooxygen	264..389	CDD:279429	46/154 (30%)
		Cu2_monoox_C	410..565	CDD:281675	54/171 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463768
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3568
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4822
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1472750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800