Protein Alignment CG5235 and Moxd1

DIOPT Version :10

• Sequence 1: NP_648833.1
• Gene: CG5235 / 39758
• FlyBaseID: FBgn0036565
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_220095.5
• Gene: Moxd1 / 294119
• RGDID: 1310033
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 198/668 - (29%)
• Similarity: 309/668 - (46%)
• Gaps: 115/668 - (17%)

  Fly    42 KNWVRNEMMDSLGLYWLKWWINANENSIYFEVTVHTRGFAGLGFSKDGRLARADMVLMWVDDATG 106
            :::....::|..|.|||.|  ......:.|.:.|.|.|:.|.|||..|.:|.||:|:..|  |.|
  Rat    60 RSYPHRVVLDPEGKYWLLW--GRQGERLAFRLEVRTNGYVGFGFSPTGTMAAADIVVGGV--AHG 120

  Fly   107 HPNVLDCHGALHPSSGPPLQDDT-QNYDVLDGKQNGTHTILKFKRKIETCDPFDIPLSADTFKVL 170
            .|.:.|    ...::...|:.|. |:|.:....:|.|||:::|.|.:.|||..|..|:..|.:|:
  Rat   121 RPYLQD----YFTNADKELEKDAQQDYHLDYAMENSTHTVIEFSRDLHTCDANDKSLTDSTVRVI 181

  Fly   171 WSIGENDPIHGNLDWQGQSRGVKALQLFSPMFTKNSHSIEGIQKWDITVNNVTIDRSMDTLYWCK 235
            |:....||......:...:||.|:|:|.:|  .|.|.....:..:|:...||.|. :..|.|||:
  Rat   182 WAYHHEDPGESGPKYHDSNRGTKSLRLLNP--EKASVLSTVLPYFDLVNQNVPIP-NKGTTYWCQ 243

  Fly   236 IVRLPELTGKQHIIGYEPLLSGKYERNVVHHMTLFECQSKIYSGSDPSSWDLWVRSAGTVC-NSN 299
            :.::|....|.|:|..||::...:| ::|||:.|::|.|.....         |...|..| :.|
  Rat   244 MFKIPIFQEKHHVIKVEPIIERGHE-SLVHHILLYQCSSNFNDS---------VLDFGHECYHPN 298

  Fly   300 LLTPRDWDSCSTPVAVWSLGSDGQFLPPHAGIPMGGASGVSYYMLEIHYDNPDGKES-VDHSGFR 363
            :  |..:.:|.|.:..|.:|.:|...|||.|:.:|......|.:||:|||||..|:. :|.||.|
  Rat   299 M--PDAFLTCETVIFAWGIGGEGFTYPPHVGLSLGMPPDPRYVLLEVHYDNPARKKGLIDSSGLR 361

  Fly   364 IHYTPNLRTYDSGILISGVSISETQLIPPGQKKYRSVGICGPSCSSVMFPKD---GIKIISGTLH 425
            ..:|.:.|.||:|::.:|:.:|....||||..::||.|.|...|.......:   ||.:.:..||
  Rat   362 FFHTTDTRRYDAGVIEAGLWVSLFHTIPPGMPEFRSEGHCTRECLEEALGTEKPSGIHVFAVLLH 426

  Fly   426 SHQAGRTISLRHVRSGKELNPIIVDENYDYRHQKVHQLANETVVLPGDYLITDCSYETKYRKRPT 490
            :|.:|:.|.|||.|.|:|:..:..|::||:..|:...|..|..:||||.|||:|.|.||.|...|
  Rat   427 AHLSGKGIRLRHFRKGEEMQLLAYDDDYDFNFQEFQYLREEQTILPGDNLITECRYNTKDRAAMT 491

  Fly   491 FGGYSTKEEMCLTFITYYPKIEMSGCYSMTPVR---EFFEMFRVY--------------QFYSLN 538
            :||.||:.||||:::.|||:|.::.|.|:..:.   :|..:..:|              |:.:|:
  Rat   492 WGGLSTRNEMCLSYLLYYPRINLTRCTSIPDIMDQLQFIGVKEIYRPVTTWPFIIKSPKQYRNLS 556

  Fly   539 MTDVENMFLYNSDYTDYSKQAKNATNKPNSGKTSKEDVIYQESLLNKLVISDPAEFHDRTFLSHL 603
            ..|..|.|.:                      |.||.|.:     ||||:|.|....    .|..
  Rat   557 FMDAMNKFKW----------------------TKKEGVSF-----NKLVLSLPVNMR----CSKA 590

  Fly   604 NQLPWHDPLFTKRVEQAFITGTHMTFCRVSKDSLSIPSEIIRYPEFTAYVKPPAACLNYLFTDNE 668
            :...|.            |.|  ||         ::|.:|.:     .|...|..|..
  Rat   591 DNAEWS------------IQG--MT---------ALPPDIKK-----PYKAEPLVCGT------- 620

  Fly   669 ELRSGSSQFFTDFTLSLL 686
               |.||:....|.|.||
  Rat   621 ---SASSRLHGVFPLPLL 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5235	NP_648833.1	DOMON	56..173	CDD:460893	40/117 (34%)
		Cu2_monooxygen	215..355	CDD:460053	44/140 (31%)
		Cu2_monoox_C	373..529	CDD:461021	61/161 (38%)
Moxd1	XP_220095.5	DOMON_DOH	68..202	CDD:187689	44/141 (31%)
		Cu2_monooxygen	224..352	CDD:460053	44/140 (31%)
		Cu2_monoox_C	371..519	CDD:461021	59/147 (40%)