Protein Alignment CG5235 and tbh-1

DIOPT Version :9

• Sequence 1: NP_001261921.1
• Gene: CG5235 / 39758
• FlyBaseID: FBgn0036565
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001257264.1
• Gene: tbh-1 / 181639
• WormBaseID: WBGene00006541
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 633
• Identity: 164/633 - (25%)
• Similarity: 263/633 - (41%)
• Gaps: 139/633 - (21%)

  Fly    58 LKW-------------WINANENSIYFEVTVHTRGFAGLGFSKDGRLARADMVLMWVDDATGHPN 109
            :||             |..|:...:.|           ||||..|....:| |||:.:   ....
 Worm   107 VKWHTDYERQLVDFSIWFGASTPDVLF-----------LGFSDFGDTNNSD-VLMYYN---SKKE 156

  Fly   110 VLDCHGALHPSSGPPLQDDTQNYDVLDGKQNGTHTILKFKRKIETCDPFDIPLSADT--FKVLWS 172
            :.|.:..........||.|.|..     ::...|.::  :||:.|||..|......|  |.:..|
 Worm   157 IKDAYTNRDFKITSDLQQDFQLL-----RKRKDHIVV--RRKLTTCDSRDYAFLPGTTQFYIAAS 214

  Fly   173 IGEND-----------------PIHGNLDWQGQSRGVKALQLFSPMFTKNSHSIEGIQKWDITVN 220
            .|..:                 .|.|..|.........||:....:...||:|.:.|.
 Worm   215 WGSTNLVDIRDKRWVVDKKFGKVIEGPTDQPNIEEEPAALEKDVKVVIVNSNSPDPIP------- 272

  Fly   221 NVTIDRSMDTLYWCKIVRLP--ELTGKQHIIGYEPLLSGKYERNVVHHMTLFECQSKI--YSGSD 281
                  :::|.|.|.|.::|  .:....|::..||.::...| ::||||.:|.|:.::  :|||
 Worm   273 ------NVETTYKCIIRKMPFDTVNNMYHVVRMEPYVTPGNE-HLVHHMEIFMCRDEVEEWSGS- 329

  Fly   282 PSSWDLWVRSAGTVCNSNLLTPRDWDSCSTPVAVWSLGSDGQFLPPHAGIPMGGASGVSYYMLEI 346
                          ||.....|:. .|||..:|.|::|......|..||:|:||....:|.|:||
 Worm   330 --------------CNDPKKPPKS-KSCSHVIAAWAMGEGPIHYPKEAGLPIGGKGKNAYVMVEI 379

  Fly   347 HYDNPD-GKESVDHSGFRIHYTPNLRTYDSGILISGVSISETQLIPPGQKKYRSVGICGPSCSSV 410
            ||:||: .|..:|.|||:...|..||.||:||:..|:..|:...:||.||.:...|.|...|:..
 Worm   380 HYNNPELHKGVIDSSGFQFFVTGQLRKYDAGIMELGLIYSDANSVPPNQKAWAMNGYCPSQCTKN 444

  Fly   411 MFPKDGIKIISGTLHSHQAGRTISLRHVRSGKELNPIIVDENYDYRHQKVHQLANETVVLPGDYL 475
            : |::||.|.:..||:|..||.:.....|||..:..:..||:|....|.:.||.....|:|||.|
 Worm   445 L-PEEGINIFASQLHAHLTGRKLFTSQYRSGVRIGDVNRDEHYSPHWQHLQQLRPVVKVMPGDTL 508

  Fly   476 ITDCSYETKYRKRPTFGGYSTKEEMCLTFITYYPKIEMSGC---YSMTPVREFF--------EMF 529
            :|.|.|:|:.|.:.|||||...:|||:.:|.|||..::..|   .|.:.:|.:|        :..
 Worm   509 VTTCVYDTRKRSKVTFGGYRIVDEMCVNYIYYYPASDVEVCKSAISNSTLRAYFSERHGMDGKRM 573

  Fly   530 RVYQFYSLNMTDVENMFLYNSDYTDYSKQAKNATNKPNSGKTSKEDVIYQESLLNKLVIS-DPAE 593
            ::...|| |:.|..|         ...::..|..|..|..             :|.|..: :|.|
 Worm   574 QISDMYS-NVKDWGN---------GVDEEFYNVLNVGNMN-------------MNCLKSNGEPFE 615

  Fly   594 FHDRTFLSHLNQLPWHDPLFTKRVEQAFITGTHMTFCRVSKDSLSIPS 641
            |..:.     ::..|.:     .....|::|:.:|    ::|....|:
 Worm   616 FESKD-----SRQSWEN-----MARPTFVSGSFIT----TRDRFQCPA 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5235	NP_001261921.1	DOMON	54..174	CDD:281361	29/130 (22%)
		Cu2_monooxygen	214..354	CDD:279429	41/144 (28%)
		Cu2_monoox_C	374..529	CDD:281675	56/165 (34%)
tbh-1	NP_001257264.1	DOMON	102..215	CDD:281361	28/129 (22%)
		Cu2_monooxygen	270..387	CDD:279429	42/146 (29%)
		Cu2_monoox_C	408..562	CDD:281675	55/154 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4822
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1472750at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.870