DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Diap1 and birc6

DIOPT Version :9

Sequence 1:	NP_001261916.1	Gene:	Diap1 / 39753	FlyBaseID:	FBgn0260635	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_021328806.1	Gene:	birc6 / 796547	ZFINID:	ZDB-GENE-091202-7	Length:	4929	Species:	Danio rerio

Alignment Length:	421	Identity:	101/421 - (23%)
Similarity:	144/421 - (34%)	Gaps:	130/421 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 EETRLKTFTDWP---LDWLDKRQLAQTGMYFTHAG---DKVKCFFCGVEIGCWEQEDQPVPEHQR 102
            |..|.:|||.||   ..|.....:||.|.|...|.   |:..||.|.|.:.|||..|:|..||:|
Zfish   245 EANRRETFTSWPHSGYRWAQPDPMAQAGFYHQPASTGDDRAMCFTCSVCLVCWEPTDEPWSEHER 309

  Fly   103 WSPNCPLLRRRTTNNVPI------------NAEALDRILPPISY----------------DICGA 139
            .|||||.::...|.|||:            :|:..|:|   :.|                .||..
Zfish   310 HSPNCPFVKGEHTQNVPLSVTLATSPAQFPSADGSDKI---VCYGFGSCPHFLATATKRGKICIW 371

  Fly   140 NDSTLEMREHAYAEGVIP-----MSQLIQSIGMNAVNAAGSVTGTAAPQPRVT---VATHASTAT 196
            :.|.| |:.|...| |.|     :.|||.| |....|    :|||...:|.::   .||..|...
Zfish   372 DVSKL-MKVHLKFE-VNPYDPAILRQLILS-GSEQQN----LTGTELRRPTLSWLEEATCCSDLP 429

  Fly   197 QATGDV-----------------------QPETCRPS----AASGNYFPQYPEYAIETARLRTFE 234
            :..||.                       |.||...|    |.|....|:..::.:..:.|   |
Zfish   430 KLEGDSDDQIEDSDSEEHSRSESVTGPLGQKETMEVSLGVTALSVLQQPEKLQWEVVASVL---E 491

  Fly   235 AWPRNLKQ----KPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKL 295
            ...::|::    .||.|...      ..|:.:              |.|.|.|.:     .|..|
Zfish   492 DTVKDLEELGANPPHSLGPP------KADKAK--------------DRPAEHHNI-----PFPCL 531

  Fly   296 MKGQLYIDTVAAKPVLAEEKEESSSIGGVAVASTQASEEEQ----------QTSLSSEEAVSGDV 350
            :.|.|.....||...|.......|....|..|:.:....:|          .|.|.|
Zfish   532 LAGGLLSYRSAASSPLGPPPSRRSMDSPVRTAAPEGLAPDQGPMEIESCNPSTDLGS-------- 588

  Fly   351 APSVAPTAATRIFNKIVEATAVATPSTNSSG 381
             |::.|.|.......::...::......|||
Zfish   589 -PNLPPAAPVHRTMPVLLLYSIKEADEKSSG 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Diap1	NP_001261916.1	BIR	44..112	CDD:197595	31/73 (42%)
		BIR	226..295	CDD:197595	12/72 (17%)
		zf-C3HC4_3	387..432	CDD:290631
birc6	XP_021328806.1	BIR	246..319	CDD:237989	30/72 (42%)
		BIRC6	3501..3664	CDD:315107
		UBCc	4669..4807	CDD:238117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810