DRSC/TRiP Functional Genomics Resources

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Protein Alignment Diap1 and mylip

DIOPT Version :9

Sequence 1:NP_001261916.1 Gene:Diap1 / 39753 FlyBaseID:FBgn0260635 Length:438 Species:Drosophila melanogaster
Sequence 2:NP_001017059.2 Gene:mylip / 549813 XenbaseID:XB-GENE-949814 Length:445 Species:Xenopus tropicalis


Alignment Length:381 Identity:76/381 - (19%)
Similarity:123/381 - (32%) Gaps:124/381 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 PINAEALDRILPPISY-------------DICGANDSTLEMR----EHAYAEGVIPMS------- 159
            |..|..|..:|..:.|             |:||.:..|..:.    :|...||:...|       
 Frog   113 PAQAVELSALLAQMEYGDYSVNTATYSLQDLCGKDIDTAALESIIAKHKSLEGLSQASGEYQFLQ 177

  Fly   160 ---------------------QLIQSIGMNAVNAAGSVTGTAAPQPRVT-----VATHAS----- 193
                                 :||..||...::....   ..:|..|:|     :||.:.     
 Frog   178 IVSTLENYGVEWHSVRDAEGQKLIVGIGPEGISLCKE---DFSPINRITYPVIQMATQSGKNVYL 239

  Fly   194 TATQATGD---VQPETCRPSAASGNY---FPQYPEYAIETARLRTFEAWPRNLKQKPHQLAEAGF 252
            |.|:.:|:   :..:.....||||.|   ...:..|..:|........:.|:|  |.|.   |.|
 Frog   240 TITKESGNSLVLLFKVVSTRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDL--KGHL---ASF 299

  Fly   253 FYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKLMKGQLYIDTV--AAKPVLAEEK 315
            |.                   |||                  :..|:.|:..:  .:|.|....:
 Frog   300 FL-------------------NDN------------------INVGKKYVFDIRRTSKEVYDHAR 327

  Fly   316 EESSSIGGVAVASTQASEEEQQTSLSSEEAVSGDVAPSVAPTAATRIFNKIVEATAVATPSTNSS 380
            ....:.|.|.:.|.....|......:||..::.:...|::......:..|:              
 Frog   328 RALYNAGIVDLVSGSGHSEPSSPLKTSESNMNCNSCESLSCQQTKALQEKL-------------- 378

  Fly   381 GSTSIPEEKLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRKPFTDVMRVY 436
              ..:.|..||.:|...|.|:||.||||:|.|..||:.:..||:||.....|..|:
 Frog   379 --RKLKEAMLCMLCCEEEINSAFCPCGHMVCCEGCATQLQSCPVCRASVEHVQHVF 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Diap1NP_001261916.1 BIR 44..112 CDD:197595
BIR 226..295 CDD:197595 11/68 (16%)
zf-C3HC4_3 387..432 CDD:290631 20/44 (45%)
mylipNP_001017059.2 FERM_F1_MYLIP 1..81 CDD:340624
B41 5..190 CDD:214604 13/76 (17%)
FERM_C_MYLIP_IDOL 185..295 CDD:270016 22/114 (19%)
RING-HC_MYLIP 386..423 CDD:319437 18/36 (50%)
RING-HC finger (C3HC4-type) 387..421 CDD:319437 16/33 (48%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1340284at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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