Protein Alignment Notum and notum1a

DIOPT Version :10

• Sequence 1: NP_730096.2
• Gene: Notum / 39751
• FlyBaseID: FBgn0044028
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001155126.1
• Gene: notum1a / 570510
• ZFINID: ZDB-GENE-120807-2
• Length: 500
• Species: Danio rerio
• Alignment Length: 619
• Identity: 190/619 - (30%)
• Similarity: 280/619 - (45%)
• Gaps: 192/619 - (31%)

  Fly    49 LDAASLQEKDPLRDTSMNMIQRNYMVMHSASGSG-DHSRSLKRANLANTSITCNDGSHAGFYLRK 112
            ||..:::|.   .|..|..::.....::..|... |:  .:|...|.|||:|||||:.||:||::
Zfish    59 LDFTAVEEN---MDNFMTQVKNLAQSLYPCSAQKLDY--DMKLHFLENTSVTCNDGTPAGYYLKE 118

  Fly   113 HPSSKKWIVLLEGGWHCFDVRSCRSRWMRLRHLMTSSQWPETRDVGGILSPHPEENPYWHNANHV 177
            ...||:|::.|||||:||:..:|.||:..:|.||:||:||:|:...|:||..|||||:|.|||.|
Zfish   119 SKGSKRWLIFLEGGWYCFNKENCDSRYETMRRLMSSSKWPQTKTGTGMLSSLPEENPHWWNANMV 183

  Fly   178 LIPYCSSDSWSGTRTEPDTSDRENSWRFMGALILRQVIAELIPVGLGRVPGGELMLVGSSAGGMG 242
            .|||||||.|||...:.|    :|.:.|||:||:::|:.:|:..||....  .|:|.||||||.|
Zfish   184 FIPYCSSDVWSGASPKTD----QNDYAFMGSLIIKEVVKDLLSKGLDNAK--ILLLAGSSAGGTG 242

  Fly   243 VMLNLDRIRDFLVNEKKLQITVRGVSDSGWFLDREPY------TPAAVASNEAVRQGWKLWQGLL 301
            |:||:|.:.:.|.......|.|||:||||||||.:.|      .....|..|.:::|.|.|.|::
Zfish   243 VLLNVDSVSELLEELGHTNIQVRGLSDSGWFLDNKQYRCTDCVDTINCAPTEVIKRGIKYWGGVV 307

  Fly   302 PEECTKSYPTEPWRCYYGYRLYPTLKTPLFVFQWLFDEAQMRVDNV---GAPVTPQQWNYIHEMG 363
            ||.|.::|..:.|.|::||::|||:|.|:|:.||||||||:.|||:   |.||...||.||..:|
Zfish   308 PERCRQAYEGKEWNCFFGYKVYPTIKRPVFIVQWLFDEAQLTVDNIHLTGQPVQEGQWRYIQNLG 372

  Fly   364 GALRSSLDNVSAVFAPSCIGHGVLFKRDWVNIKIDDISLPSALRCWEHSTRSRRHDKLKRSTEPS 428
            ..||::|.:|.|:|||:|:.|..:.:..|.::::...|||.||.||:.|
Zfish   373 TELRNTLKDVPAMFAPACLSHEFITRNYWTDVQVKGTSLPRALHCWDRS---------------- 421

  Fly   429 TAVSHPEHANNQRHQRHRQRLQRQKHNNVAQSGGQQRKHNHLSKEEREERKRLRQEQRQRRKQRR 493
                                ||....||
Zfish   422 --------------------LQDTSRNN------------------------------------- 429

  Fly   494 RQQQQKKANGGQEHRNKKDNSPKSSNGNDQRKQRRRQQLTAEERQEQRKRRRKAQQQQMKMQREQ 558
                               .||
Zfish   430 -------------------KSP------------------------------------------- 432

  Fly   559 PAAGVFLEASAPQKTRSSNNASAGTKSKKRHRVPRVPEKCGLRLLERCSWPQCNHSCPTLTNPMT 623
                                                |:.|.:.|::.|.||.||.:|||:.:..|
Zfish   433 ------------------------------------PKGCPVHLIDSCPWPHCNPTCPTIRDQST 461

  Fly   624 GEEMRFLELLTAFGLDIEAVAAALGVDMHTLNNM 657
            |:||..::.|...|.|::.:|...|:|...|..|
Zfish   462 GQEMNVIQFLMHMGFDVQKMAHQQGMDPSKLLGM 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Notum	NP_730096.2	PAE	92..412	CDD:460874	152/328 (46%)
notum1a	NP_001155126.1	PAE	86..421	CDD:460874	155/342 (45%)