Protein Alignment Notum and Notum

DIOPT Version :9

• Sequence 1: NP_730096.2
• Gene: Notum / 39751
• FlyBaseID: FBgn0044028
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: XP_006247949.1
• Gene: Notum / 303743
• RGDID: 1307119
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 631
• Identity: 195/631 - (30%)
• Similarity: 280/631 - (44%)
• Gaps: 206/631 - (32%)

  Fly    56 EKDPLRDTSMNMIQRNYMVMHSASGSGDHSRSLKRAN-------LANTSITCNDGSHAGFYLRKH 113
            |..||..|::.....::|....:.....:..|.::.|       |.|||:||||||.||:||::.
  Rat    92 ESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKES 156

  Fly   114 PSSKKWIVLLEGGWHCFDVRSCRSRWMRLRHLMTSSQWPETRDVGGILSPHPEENPYWHNANHVL 178
            ..|::|::.|||||:||:..:|.||:..:|.||:|..||.||...||||..|||||:|.|||.|.
  Rat   157 KGSRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVF 221

  Fly   179 IPYCSSDSWSGTRTEPDTSDRENSWRFMGALILRQVIAELIPVGLGRVPGGE-LMLVGSSAGGMG 242
            |||||||.|||...:.:    :|.:.|||:||:::|:.||:..||.   |.: |:|.||||||.|
  Rat   222 IPYCSSDVWSGASPKSE----KNEYAFMGSLIIQEVVRELLVKGLS---GAKVLLLAGSSAGGTG 279

  Fly   243 VMLNLDRIRDFLVNEKKLQITVRGVSDSGWFLDREPYTPA------AVASNEAVRQGWKLWQGLL 301
            |:||:||:.:.|.......|.|||::|||||||.:.|..:      ..|..||:|:|.:.|.|::
  Rat   280 VLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTEAIRRGIRYWSGMV 344

  Fly   302 PEECTKSYPT-EPWRCYYGYRLYPTLKTPLFVFQWLFDEAQMRVDNV---GAPVTPQQWNYIHEM 362
            ||.|.:.:.. |.|.|::||::||||:.|:||.||||||||:.||||   |.||...||.||..:
  Rat   345 PERCQRQFKEGEEWNCFFGYKIYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGQWLYIQNL 409

  Fly   363 GGALRSSLDNVSAVFAPSCIGHGVLFKRDWVNIKIDDISLPSALRCWEHSTRSRRHDKLKRSTEP 427
            |..||.:|.:|.|.|||:|:.|.::.:..|.::::...|||.||.||:.|.    ||.
  Rat   410 GRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHCWDRSF----HDS------- 463

  Fly   428 STAVSHPEHANNQRHQRHRQRLQRQKHNNVAQSGGQQRKHNHLSKEEREERKRLRQEQRQRRKQR 492
                                                                             
  Rat   464 ----------------------------------------------------------------- 463

  Fly   493 RRQQQQKKANGGQEHRNKKDNSPKSSNGNDQRKQRRRQQLTAEERQEQRKRRRKAQQQQMKMQRE 557
                                                                             
  Rat   464 ----------------------------------------------------------------- 463

  Fly   558 QPAAGVFLEASAPQKTRSSNNASAGTKSKKRHRVPRVPEK-CGLRLLERCSWPQCNHSCPTLTNP 621
                                           |:..:.|.| |...|::.|.||.||.||||:.:.
  Rat   464 -------------------------------HKASKTPMKGCPFHLVDSCPWPHCNPSCPTIRDQ 497

  Fly   622 MTGEEMRFLELLTAFGLDIEAVAAALGVDMHTLNNMERTELVNMLT 667
            .||:||...:.|...|.|::.||...|        ||.::|:.:|:
  Rat   498 FTGQEMNVAQFLMHMGFDVQTVAQQQG--------MEPSKLLGILS 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Notum	NP_730096.2	PAE	99..409	CDD:281299	151/320 (47%)
Notum	XP_006247949.1	PAE	124..459	CDD:281299	161/352 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	330	1.000	Domainoid score	I1121
eggNOG	1	0.900	-	-		E1_KOG4287
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45335
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D203180at33208
OrthoFinder	1	1.000	-	-		FOG0004840
OrthoInspector	1	1.000	-	-		oto96763
orthoMCL	1	0.900	-	-		OOG6_102699
Panther	1	1.100	-	-	LDO	PTHR21562
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3973
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.780