Protein Alignment Notum and notum

DIOPT Version :10

• Sequence 1: NP_730096.2
• Gene: Notum / 39751
• FlyBaseID: FBgn0044028
• Length: 671
• Species: Drosophila melanogaster
• Sequence 2: NP_001120228.2
• Gene: notum / 100145278
• XenbaseID: XB-GENE-996986
• Length: 488
• Species: Xenopus tropicalis
• Alignment Length: 667
• Identity: 200/667 - (29%)
• Similarity: 288/667 - (43%)
• Gaps: 213/667 - (31%)

  Fly    28 LTLLLLLATFS---------QLPAVCSSSILDAASLQEKDPLRDTSMNMIQRNYMVMHSASGSGD 83
            :||||||:..:         :...:..||...:....|..||..|::.....|:|....:.....
 Frog     7 ITLLLLLSIITVGSRKTWRRRGQQIIPSSRERSEGGGESFPLDFTAVEGNMDNFMAQIKSLAQSL 71

  Fly    84 HSRSLKRAN-------LANTSITCNDGSHAGFYLRKHPSSKKWIVLLEGGWHCFDVRSCRSRWMR 141
            :..|.:|.:       |.|.|:||||||.||:||::...|::|:|.|||||:|....:|..|:..
 Frog    72 YPCSAQRLDDEMKLHILHNKSVTCNDGSPAGYYLKESKGSRRWLVFLEGGWYCISRENCDLRYDT 136

  Fly   142 LRHLMTSSQWPETRDVGGILSPHPEENPYWHNANHVLIPYCSSDSWSGTRTEPDTSDRENSWRFM 206
            :|.||:|..||..:...||||..|||||:|.|||.|.|||||||.|||  ..|.|  .::.:.||
 Frog   137 MRRLMSSKAWPPAKTASGILSTQPEENPHWWNANMVFIPYCSSDVWSG--ASPKT--EKSGYAFM 197

  Fly   207 GALILRQVIAELIPVGLGRVPGGELMLVGSSAGGMGVMLNLDRIRDFLVNEKKLQITVRGVSDSG 271
            |:||:::|:.||:..||....  .|:|.||||||.||:||:|.:.|.|.......|.|||:||||
 Frog   198 GSLIIQEVVKELLGKGLDTAK--VLLLAGSSAGGTGVLLNVDLVADQLEELGFPGIQVRGLSDSG 260

  Fly   272 WFLDREPYTPA------AVASNEAVRQGWKLWQGLLPEECTKSYPT-EPWRCYYGYRLYPTLKTP 329
            ||||.:.|...      ..|..||:::|.:.|..::||.|.:.:.. |.|.|::||::||||::|
 Frog   261 WFLDNKQYRRTDCTDIITCAPTEAIQRGIRYWNSVVPERCKQQFKEGEEWNCFFGYKIYPTLRSP 325

  Fly   330 LFVFQWLFDEAQMRVDNV---GAPVTPQQWNYIHEMGGALRSSLDNVSAVFAPSCIGHGVLFKRD 391
            :||.||||||||:.||||   |.||...||.||..:|..||::|.:|.|.|||:|:.|.|:.:..
 Frog   326 VFVVQWLFDEAQLTVDNVHLSGQPVQESQWLYIQNLGQELRNTLKDVGASFAPACLAHEVITRSH 390

  Fly   392 WVNIKIDDISLPSALRCWEHSTRSRRHDKLKRSTEPSTAVSHPEHANNQRHQRHRQRLQRQKHNN 456
            |..|::...|||.||.||:.|                                    ||....|:
 Frog   391 WTEIQVRGTSLPRALHCWDRS------------------------------------LQETNKNS 419

  Fly   457 VAQSGGQQRKHNHLSKEEREERKRLRQEQRQRRKQRRRQQQQKKANGGQEHRNKKDNSPKSSNGN 521
                                                                             
 Frog   420 ----------------------------------------------------------------- 419

  Fly   522 DQRKQRRRQQLTAEERQEQRKRRRKAQQQQMKMQREQPAAGVFLEASAPQKTRSSNNASAGTKSK 586
                                                                             
 Frog   420 ----------------------------------------------------------------- 419

  Fly   587 KRHRVPRVPEK-CGLRLLERCSWPQCNHSCPTLTNPMTGEEMRFLELLTAFGLDIEAVAAALGVD 650
                  :||.| |...|::.|.|||||.:||::.:..||:||..::.|...|.|::.:|:..|
 Frog   420 ------KVPLKGCPFHLMDSCPWPQCNPTCPSIRDHFTGQEMSVVQFLMHLGFDVQKMASQQG-- 476

  Fly   651 MHTLNNMERTELVNMLT 667
                  ||..:|:.:|:
 Frog   477 ------MEPGKLLGVLS 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Notum	NP_730096.2	PAE	92..412	CDD:460874	154/336 (46%)
notum	NP_001120228.2	PAE	75..411	CDD:460874	156/341 (46%)