Protein Alignment LHX1 and CG4328

DIOPT Version :10

• Sequence 1: NP_005559.2
• Gene: LHX1 / 3975
• HGNCID: 6593
• Length: 406
• Species: Homo sapiens
• Sequence 2: NP_648567.2
• Gene: CG4328 / 39405
• FlyBaseID: FBgn0036274
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 238
• Identity: 81/238 - (34%)
• Similarity: 127/238 - (53%)
• Gaps: 36/238 - (15%)

Human     4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCF-GTKCAGCA 67
            ||.|.:||.||:::.|::.::|..|::|..|..:|...|::|||||||:.|:.|.: ...|.||.
  Fly   199 CAHCCQPICDRYIMRVVENSFHEGCLKCTACSLHLVHSCYAREGKLYCRVDYERLYIRNHCLGCG 263

Human    68 QGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLHS 132
            ..|:..:||.|....||||.||.|::|...|..||: |::.:.:..|:.||      .||..:..
  Fly   264 LKIAADELVMRCHENVFHLKCFACVVCGALLKKGEQ-YVVKQGQLFCRFDY------EKEVEMLQ 321

Human   133 ATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGPRTTIKAKQLETLKA 197
            ........|.|    |..|..:                      |.||  |||.:..:|....||
  Fly   322 GYDFYGDELFP----PKLDGRR----------------------GPKR--PRTILNTQQRRAFKA 358

Human   198 AFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQ 240
            :|..:|||.|.:||.||::|||::|::||||||:|:|.:::::
  Fly   359 SFEVSPKPCRKVRENLAKDTGLSLRIVQVWFQNQRAKVKKIQK 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LHX1	NP_005559.2	LIM1_Lhx1_Lhx5	4..55	CDD:188753	21/50 (42%)
		LIM2_Lhx1_Lhx5	63..118	CDD:188761	20/54 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..187		10/58 (17%)
		Homeodomain	181..237	CDD:459649	27/55 (49%)
		dnaA	<263..>382	CDD:455861
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	293..374
CG4328	NP_648567.2	LIM1_Lmx1b	199..251	CDD:188757	22/51 (43%)
		LIM	259..313	CDD:413332	20/54 (37%)
		COG5576	<332..439	CDD:227863	33/98 (34%)
		HOX	341..393	CDD:197696	27/53 (51%)