Protein Alignment hzg and CTDP1

DIOPT Version :10

• Sequence 1: NP_001261912.1
• Gene: hzg / 39748
• FlyBaseID: FBgn0036556
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_004706.3
• Gene: CTDP1 / 9150
• HGNCID: 2498
• Length: 961
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 67/296 - (22%)
• Similarity: 118/296 - (39%)
• Gaps: 78/296 - (26%)

  Fly    96 DQQRYLLPQVRLTDMHRK---CMVIDLDETLVHSSFKPIPNADFIVPVEIDGTVH--------QV 149
            ||||          :||.   .:::|||:||:|::      ......:...|..|        .:
Human   173 DQQR----------LHRNRKLVLMVDLDQTLIHTT------EQHCQQMSNKGIFHFQLGRGEPML 221

  Fly   150 YVLKRPHVDEFLQKMGELYECVLFTASLAKYADPVADLLD-KWNVFRAR-LFRESCV--YYRGNY 210
            :...|||..:||:|:.:|||..:||.....||..:|..|| :..:|..| |.|:.|:  :.:...
Human   222 HTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGN 286

  Fly   211 IKDLNRLGRDLQKIVIVDNSPASYIFHPDNAVPVKS--WFDDVTDCEL----RELIPLFEKLSKV 269
            :::|...|..:  :.|:|:....:.|.| |.:.||.  :|....|...    ||    .:...||
Human   287 LRNLFPCGDSM--VCIIDDREDVWKFAP-NLITVKKYVYFQGTGDMNAPPGSRE----SQTRKKV 344

  Fly   270 D-SVYSVLCNSNQPLNNQTNQQQHPQELQQAP-----NQLHQQLQQQQQQQTISATTVITQATT- 327
            : |..:.:...:.|:.:       |:.:.|||     |.|.:..::      ::.:...|...:
Human   345 NHSRGTEVSEPSPPVRD-------PEGVTQAPGVEPSNGLEKPARE------LNGSEAATPRDSP 396

  Fly   328 -------------LSAPTMLNQQQTSPPSPQSELLQ 350
                         ..|||. :|:....|.||....|
Human   397 RPGKPDERDIWPPAQAPTS-SQELAGAPEPQGSCAQ 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hzg	NP_001261912.1	HIF-SF_euk	112..270	CDD:274055	44/178 (25%)
CTDP1	NP_004706.3	Biotinyl_lipoyl_domains	21..111	CDD:448245
		FCP1_euk	177..323	CDD:131304	40/154 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..589		22/122 (18%)
		PRK07764	<331..539	CDD:236090	21/119 (18%)
		BRCT_CTDP1	621..723	CDD:349361
		FCP1_C	716..961	CDD:462751
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	730..752
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	780..949